Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy.
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Gregory W. Kauffman | David S. Ramirez | L. Pustilnik | A. Stepan | É. Hajós‐Korcsok | P. Verhoest | K. Bales | Christopher W. am Ende | S. Jenkinson | Martin Pettersson | Douglas S. Johnson | C. Stiff | Betty A Pettersen | J. Humphrey | Christopher J. Helal | Stefanus J. Steyn | T. Butler | Longfei Xie | Edelweiss Evrard | Kathleen M. Wood | B. Boscoe | Eddie Yang | D. A. Rankic