MKK3 modulates JNK-dependent cell migration and invasion

[1]  Ping Huang,et al.  Tankyrase Mediates K63-Linked Ubiquitination of JNK to Confer Stress Tolerance and Influence Lifespan in Drosophila. , 2018, Cell reports.

[2]  Chenxi Wu,et al.  Pontin/Tip49 negatively regulates JNK-mediated cell death in Drosophila , 2018, Cell Death Discovery.

[3]  Hongzhuan Chen,et al.  Epigenetic silencing of miR-483-3p promotes acquired gefitinib resistance and EMT in EGFR-mutant NSCLC by targeting integrin β3 , 2018, Oncogene.

[4]  Yongli Dong,et al.  PP6 Disruption Synergizes with Oncogenic Ras to Promote JNK-Dependent Tumor Growth and Invasion. , 2017, Cell reports.

[5]  L. Xue,et al.  Myc suppresses tumor invasion and cell migration by inhibiting JNK signaling , 2017, Oncogene.

[6]  Wenzhe Li,et al.  Hippo signaling promotes JNK-dependent cell migration , 2017, Proceedings of the National Academy of Sciences.

[7]  S. Ohsawa,et al.  The ligand Sas and its receptor PTP10D drive tumour-suppressive cell competition , 2017, Nature.

[8]  Ping Huang,et al.  Regulation of Hippo signalling by p38 signalling , 2016, Journal of molecular cell biology.

[9]  L. Xue,et al.  Rho1–Wnd signaling regulates loss-of-cell polarity-induced cell invasion in Drosophila , 2016, Oncogene.

[10]  Chuan-Qi Zhong,et al.  The p38 Pathway Regulates Oxidative Stress Tolerance by Phosphorylation of Mitochondrial Protein IscU*♦ , 2014, The Journal of Biological Chemistry.

[11]  B. Fernandez,et al.  Drosophila actin-Capping Protein limits JNK activation by the Src proto-oncogene , 2014, Oncogene.

[12]  N. Copeland,et al.  Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse. , 2013, Developmental biology.

[13]  Wenzhe Li,et al.  Src42A modulates tumor invasion and cell death via Ben/dUev1a-mediated JNK activation in Drosophila , 2013, Cell Death and Disease.

[14]  P. Humbert,et al.  Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation , 2013, Journal of Cell Science.

[15]  Wenzhe Li,et al.  dUev1a modulates TNF-JNK mediated tumor progression and cell death in Drosophila. , 2013, Developmental biology.

[16]  A. Faussat,et al.  Caspase-3 Is Involved in the Signalling in Erythroid Differentiation by Targeting Late Progenitors , 2013, PloS one.

[17]  J. Taipale,et al.  Systematic screening of a Drosophila ORF library in vivo uncovers Wnt/Wg pathway components. , 2013, Developmental cell.

[18]  Cayetano Gonzalez,et al.  Drosophila melanogaster: a model and a tool to investigate malignancy and identify new therapeutics , 2013, Nature Reviews Cancer.

[19]  H. Richardson,et al.  Death takes a holiday—non‐apoptotic role for caspases in cell migration and invasion , 2013, EMBO reports.

[20]  Pierre Hainaut,et al.  Targeting the hallmarks of cancer: towards a rational approach to next-generation cancer therapy. , 2013, Current opinion in oncology.

[21]  H. Richardson,et al.  The Scribble-Dlg-Lgl polarity module in development and cancer: from flies to man. , 2012, Essays in biochemistry.

[22]  A. Gingras,et al.  High-Resolution Protein Interaction Map of the Drosophila melanogaster p38 Mitogen-Activated Protein Kinases Reveals Limited Functional Redundancy , 2012, Molecular and Cellular Biology.

[23]  D. Bohmann,et al.  A Versatile ΦC31 Based Reporter System for Measuring AP-1 and Nrf2 Signaling in Drosophila and in Tissue Culture , 2012, PloS one.

[24]  T. Sakurai,et al.  Expression of mesenchymal-related genes by the bovine trophectoderm following conceptus attachment to the endometrial epithelium. , 2012, Reproduction.

[25]  Fei Chen.  JNK-induced apoptosis, compensatory growth, and cancer stem cells. , 2012, Cancer research.

[26]  Ross L Cagan,et al.  Drosophila cancer models , 2012, Developmental dynamics : an official publication of the American Association of Anatomists.

[27]  Wenzhe Li,et al.  NOPO modulates Egr-induced JNK-independent cell death in Drosophila , 2011, Cell Research.

[28]  Sanjay Nag,et al.  A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila. , 2011, Developmental cell.

[29]  N. Dyson,et al.  Modeling tumor invasion and metastasis in Drosophila , 2011, Disease Models & Mechanisms.

[30]  Robert A. Weinberg,et al.  Tumor Metastasis: Molecular Insights and Evolving Paradigms , 2011, Cell.

[31]  E. Hafen,et al.  MK2-Dependent p38b Signalling Protects Drosophila Hindgut Enterocytes against JNK-Induced Apoptosis under Chronic Stress , 2011, PLoS genetics.

[32]  A. Jimeno,et al.  Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy , 2011, Nature Medicine.

[33]  Jessica E. Bolden,et al.  Identification of Novel Ras-Cooperating Oncogenes in Drosophila melanogaster: A RhoGEF/Rho-Family/JNK Pathway Is a Central Driver of Tumorigenesis , 2011, Genetics.

[34]  K. Irvine,et al.  Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors. , 2011, Developmental biology.

[35]  A. Abdollahi,et al.  Phenotype-assisted transcriptome analysis identifies FOXM1 downstream from Ras–MKK3–p38 to regulate in vitro cellular invasion , 2010, Oncogene.

[36]  J. C. Pastor-Pareja,et al.  Interaction between RasV12 and scribble clones induces tumour growth and invasion , 2009, Nature.

[37]  S. Hasnain,et al.  Baculovirus P35 protein: An overview of its applications across multiple therapeutic and biotechnological arenas , 2009, Biotechnology progress.

[38]  J. Bastien,et al.  A Role for p38 Stress-Activated Protein Kinase in Regulation of Cell Growth via TORC1 , 2009, Molecular and Cellular Biology.

[39]  H. Richardson,et al.  scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs , 2009, BMC Biology.

[40]  M. Therrien,et al.  The PP2C Alphabet Is a Negative Regulator of Stress-Activated Protein Kinase Signaling in Drosophila , 2009, Genetics.

[41]  K. Matsuno,et al.  D-JNK signaling in visceral muscle cells controls the laterality of the Drosophila gut. , 2007, Developmental biology.

[42]  R. Read,et al.  Differing Src signaling levels have distinct outcomes in Drosophila. , 2007, Cancer research.

[43]  D. Bohmann,et al.  JNK‐ and Fos‐regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila , 2006, The EMBO journal.

[44]  G. Pigino,et al.  JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport , 2006, Nature Neuroscience.

[45]  T. Igaki,et al.  Loss of Cell Polarity Drives Tumor Growth and Invasion through JNK Activation in Drosophila , 2006, Current Biology.

[46]  D. Larson,et al.  Csk-deficient boundary cells are eliminated from normal Drosophila epithelia by exclusion, migration, and apoptosis. , 2006, Developmental cell.

[47]  Axel Behrens,et al.  Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development , 2005, Nature.

[48]  M. Peifer,et al.  Puckered, a Drosophila MAPK phosphatase, ensures cell viability by antagonizing JNK-induced apoptosis , 2005, Development.

[49]  A. Moon,et al.  H-Ras-specific Activation of Rac-MKK3/6-p38 Pathway , 2005, Journal of Biological Chemistry.

[50]  E. Todorov.  Optimality principles in sensorimotor control , 2004, Nature Neuroscience.

[51]  Tian Xu,et al.  A Genetic Screen in Drosophila for Metastatic Behavior , 2003, Science.

[52]  H. Richardson,et al.  scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila , 2003, The EMBO journal.

[53]  Lily Yang,et al.  Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy. , 2003, Cancer research.

[54]  T. Yagi,et al.  Wengen, a Member of the Drosophila Tumor Necrosis Factor Receptor Superfamily, Is Required for Eiger Signaling* , 2002, The Journal of Biological Chemistry.

[55]  T. Aigaki,et al.  Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway , 2002, The EMBO journal.

[56]  R. Hegde,et al.  Signal sequences control gating of the protein translocation channel in a substrate-specific manner. , 2002, Developmental cell.

[57]  N. Perrimon,et al.  Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper. , 2002, Genes & development.

[58]  K. Irie,et al.  A Drosophila MAPKKK, D‐MEKK1, mediates stress responses through activation of p38 MAPK , 2001, The EMBO journal.

[59]  M. Noll,et al.  Drosophila female sexual behavior induced by sterile males showing copulation complementation. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[60]  J. Zeitlinger,et al.  Thorax closure in Drosophila: involvement of Fos and the JNK pathway. , 1999, Development.

[61]  K. Irie,et al.  The Drosophila p38 MAPK pathway is required during oogenesis for egg asymmetric development. , 1999, Genes & development.

[62]  Y. Ip,et al.  A Conserved p38 Mitogen-Activated Protein Kinase Pathway Regulates Drosophila Immunity Gene Expression , 1998, Molecular and Cellular Biology.

[63]  A. Martinez-Arias,et al.  puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila. , 1998, Genes & development.

[64]  James M. Roberts,et al.  Cyclin E-CDK2 is a regulator of p27Kip1. , 1997, Genes & development.

[65]  Y. Ip,et al.  A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila. , 1996, Genes & development.

[66]  E. Hafen,et al.  The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. , 1996, Genes & development.

[67]  Y. Tsujimoto,et al.  [Inhibition of apoptosis by a baculovirus p35 gene]. , 1996, Nihon rinsho. Japanese journal of clinical medicine.

[68]  J. Modolell,et al.  Patterning of the Drosophila nervous system: the achaete-scute gene complex. , 1992, Trends in genetics : TIG.

[69]  K. O'hare.  Searching for needles in haystacks via the polymerase chain reaction. , 1990, Trends in genetics : TIG.

[70]  I. Silver,et al.  Neurovascular control of oxygen tension in the testis and epididymis. , 1962, Journal of reproduction and fertility.