Dual Roles for Patched in Sequestering and Transducing Hedgehog
暂无分享,去创建一个
G. Struhl | Gary Struhl | Yu Chen | Yu Chen
[1] D. Kingsley,et al. The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. , 1994, Genes & development.
[2] A. Taylor,et al. A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched , 1989, Nature.
[3] G. Rubin,et al. cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in drosophila imaginal discs , 1995, Cell.
[4] G. Struhl,et al. Protein kinase A and hedgehog signaling in drosophila limb development , 1995, Cell.
[5] C. Nüsslein-Volhard,et al. Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg , 1992, Cell.
[6] Manuel Calleja,et al. Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing , 1996, Nature.
[7] M. Scott,et al. Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. , 1996, Genes & development.
[8] P. Ingham,et al. The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs. , 1990, Development.
[9] P. Ingham,et al. Regulation of wingless transcription in the Drosophila embryo. , 1993, Development.
[10] G. Rubin,et al. Analysis of genetic mosaics in developing and adult Drosophila tissues. , 1993, Development.
[11] T. Tabata,et al. Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs , 1994, Cell.
[12] J. Massagué. Receptors for the TGF-β family , 1992, Cell.
[13] Pattern Formation: Hedgehog points the way , 1994, Current Biology.
[14] Konrad Basler,et al. Organizing activity of wingless protein in Drosophila , 1993, Cell.
[15] G. Struhl,et al. Direct and Long-Range Action of a DPP Morphogen Gradient , 1996, Cell.
[16] C. Nüsslein-Volhard,et al. Mutations affecting segment number and polarity in Drosophila , 1980, Nature.
[17] K. Golic. Site-specific recombination between homologous chromosomes in Drosophila. , 1991, Science.
[18] W. Gelbart,et al. Wing formation in Drosophila melanogaster requires decapentaplegic gene function along the anterior-posterior compartment boundary , 1990, Mechanisms of Development.
[19] P. Ingham. Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo , 1993, Nature.
[20] P. Ingham. Segment polarity genes and cell patterning within the Drosophila body segment. , 1991, Current opinion in genetics & development.
[21] G. Struhl,et al. The torso receptor localizes as well as transduces the spatial signal specifying terminal body pattern in Drosophila , 1993, Nature.
[22] N. Perrimon. Serpentine Proteins Slither into the Wingless and Hedgehog Fields , 1996, Cell.
[23] N. Perrimon,et al. Use of a yeast site-specific recombinase to produce female germline chimeras in Drosophila. , 1992, Genetics.
[24] P. O’Farrell,et al. A cell-autonomous, ubiquitous marker for the analysis of Drosophila genetic mosaics. , 1994, Developmental Biology.
[25] C. Pillinger,et al. A New Member of the , 1995 .
[26] S. Cohen,et al. Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing , 1996, Nature.
[27] P. Ingham,et al. Role of the Drosophila patched gene in positional signalling , 1991, Nature.
[28] Konrad Basler,et al. Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein , 1994, Nature.
[29] Clifford J. Tabin,et al. Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein , 1996, Science.
[30] M. Noll,et al. The Drosophila smoothened Gene Encodes a Seven-Pass Membrane Protein, a Putative Receptor for the Hedgehog Signal , 1996, Cell.
[31] M. Scott,et al. Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb. , 1996, Development.
[32] N. Perrimon,et al. Cell patterning in the Drosophila segment: engrailed and wingless antigen distributions in segment polarity mutant embryos. , 1993, Development (Cambridge, England). Supplement.
[33] K. Anderson,et al. The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo , 1994, Cell.
[34] Susan M. Parkhurst,et al. Signal transduction by cAMP-dependent protein kinase A in Drosophila limb patterning , 1995, Nature.
[35] G. Struhl,et al. Similarities between trunk and spätzle, putative extracellular ligands specifying body pattern in Drosophila. , 1995, Genes & development.
[36] Jeremy Nathans,et al. A new member of the frizzled family from Drosophila functions as a Wingless receptor , 1996, Nature.
[37] W. Gelbart,et al. An extensive 3' cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila. , 1991, Development.
[38] G. Struhl,et al. Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. , 1995, Development.
[39] S. Roth,et al. The polarity of the dorsoventral axis in the drosophila embryo is defined by an extracellular signal , 1991, Cell.
[40] Roel Nusse,et al. Wnt genes , 1992, Cell.
[41] M. Scott,et al. The Drosophila patched gene encodes a putative membrane protein required for segmental patterning , 1989, Cell.
[42] H. Roelink. Tripartite signaling of pattern: interactions between Hedgehogs, BMPs and Wnts in the control of vertebrate development , 1996, Current Opinion in Neurobiology.
[43] L. Mathews,et al. Expression cloning of an activin receptor, a predicted transmembrane serine kinase , 1991, Cell.
[44] T. Jessell,et al. Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis , 1995, Cell.
[45] Mary Ellen Lane,et al. Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development , 1995, Cell.
[46] I. Guerrero,et al. Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings. , 1994, The EMBO journal.
[47] P. Ingham,et al. smoothened encodes a receptor-like serpentine protein required for hedgehog signalling , 1996, Nature.
[48] E. Sánchez-Herrero,et al. The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development. , 1994, The EMBO journal.
[49] R. L. Johnson,et al. patched overexpression alters wing disc size and pattern: transcriptional and post-transcriptional effects on hedgehog targets. , 1995, Development.
[50] M. Tessier-Lavigne,et al. Long-range sclerotome induction by sonic hedgehog: Direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway , 1995, Cell.
[51] J. Hooper. Distinct pathways for autocrine and paracrine Wingless signalling inDrosophila embryos , 1994, Nature.
[52] C. K. Motzny,et al. The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways , 1995, Mechanisms of Development.