Impact of a pharmacist-facilitated hospital discharge program: a quasi-experimental study.

BACKGROUND Medication discrepancies are common at hospital discharge and can result in adverse events, hospital readmissions, and emergency department visits. Our objectives were to characterize medication discrepancies at hospital discharge and test the effects of a pharmacist intervention on health care utilization following discharge. METHODS We used a prospective, alternating month quasi-experimental design to compare outcomes of patients receiving the intervention (n = 358) with controls (n = 366). All patients were discharged to home and were at high risk for medication-related problems following discharge because of the number or types of medications they were prescribed, multiple medication changes during hospitalization, or problems managing medications. The intervention consisted of medication therapy assessment, medication reconciliation, screening for adherence concerns, patient counseling and education, and postdischarge telephone follow-up. The primary outcomes were 14-day and 30-day readmission rates and emergency department visits within 72 hours of discharge. Medication discrepancies occurring at discharge were also characterized. RESULTS Medication discrepancies at discharge were identified in 33.5% of intervention patients and 59.6% of control patients (P < .001). Although all discrepancies were resolved in the intervention group prior to discharge, readmission rates did not differ significantly between groups at 14 days (12.6% vs 11.5%; P = .65) and 30 days (22.1% vs 18%; P = .17), nor did emergency department visits (2.8% vs 2.2%, respectively; P = .60). CONCLUSION While our intervention improved the quality of patient discharge by identifying and reconciling medication discrepancies at discharge, there was no effect on postdischarge health care resource utilization.

[1]  Stephen A. Martin,et al.  A Reengineered Hospital Discharge Program to Decrease Rehospitalization , 2009, Annals of Internal Medicine.

[2]  Greg Ogrinc,et al.  Publication guidelines for improvement studies in health care: evolution of the SQUIRE Project. , 2008, Annals of internal medicine.

[3]  Annemarie Cesta,et al.  Medication Reconciliation at Hospital Discharge: Evaluating Discrepancies , 2008, The Annals of pharmacotherapy.

[4]  G. Pope,et al.  THE MEDICARE PHYSICIAN GROUP PRACTICE DEMONSTRATION: LESSONS LEARNED ON IMPROVING QUALITY AND EFFICIENCY IN HEALTH CARE , 2008 .

[5]  A. Melander,et al.  Systematic Review of the Incidence and Characteristics of Preventable Adverse Drug Events in Ambulatory Care , 2007, The Annals of pharmacotherapy.

[6]  L. Halasyamani,et al.  Transition of care for hospitalized elderly patients--development of a discharge checklist for hospitalists. , 2006, Journal of hospital medicine.

[7]  P. Mistiaen,et al.  Telephone follow-up, initiated by a hospital-based health professional, for postdischarge problems in patients discharged from hospital to home. , 2006, The Cochrane database of systematic reviews.

[8]  A. Siu,et al.  Medication reconciliation for reducing drug-discrepancy adverse events. , 2006, The American journal of geriatric pharmacotherapy.

[9]  Jeffrey L Schnipper,et al.  Clinical pharmacists and inpatient medical care: a systematic review. , 2006, Archives of internal medicine.

[10]  J. Hanlon,et al.  Incidence and predictors of all and preventable adverse drug reactions in frail elderly persons after hospital stay. , 2006, The journals of gerontology. Series A, Biological sciences and medical sciences.

[11]  E. Etchells,et al.  Reconcilable differences: correcting medication errors at hospital admission and discharge , 2006, Quality and Safety in Health Care.

[12]  Jennifer L. Kirwin,et al.  Role of pharmacist counseling in preventing adverse drug events after hospitalization. , 2006, Archives of internal medicine.

[13]  J. Schnipper,et al.  Clinical Pharmacists and Inpatient Medical Care , 2006 .

[14]  N. MacKinnon,et al.  Drug-therapy problems, inconsistencies and omissions identified during a medication reconciliation and seamless care service. , 2005, Healthcare quarterly.

[15]  Sung-joon Min,et al.  Posthospital medication discrepancies: prevalence and contributing factors. , 2005, Archives of internal medicine.

[16]  D. Bates,et al.  Adverse drug events occurring following hospital discharge , 2005, Journal of General Internal Medicine.

[17]  P. Phillips,et al.  Does the addition of a pharmacist transition coordinator improve evidence-based medication management and health outcomes in older adults moving from the hospital to a long-term care facility? Results of a randomized, controlled trial. , 2004, The American journal of geriatric pharmacotherapy.

[18]  D. Bates,et al.  Risk Factors for Adverse Drug Events Among Older Adults in the Ambulatory Setting , 2004, Journal of the American Geriatrics Society.

[19]  S. McCreadie,et al.  Improving information flow and documentation for clinical pharmacy services. , 2004, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[20]  D. Bates,et al.  The Incidence and Severity of Adverse Events Affecting Patients after Discharge from the Hospital , 2003, Annals of Internal Medicine.

[21]  K. Kerr,et al.  The impact of follow-up telephone calls to patients after hospitalization. , 2002, The American journal of medicine.

[22]  A. Haines,et al.  A pharmacy discharge plan for hospitalized elderly patients--a randomized controlled trial. , 2001, Age and ageing.

[23]  H. Welch,et al.  Telephone care as an adjunct to routine medical follow-up. A negative randomized trial. , 2000, Effective clinical practice : ECP.

[24]  H. L. Lipton,et al.  The impact of clinical pharmacists' consultations on geriatric patients' compliance and medical care use: a randomized controlled trial. , 1994, The Gerontologist.