The cerebral blood flow in male subjects as measured by the nitrous oxide technique; normal values for blood flow, oxygen utilization, glucose utilization and peripheral resistance, with observations on the effect of tilting and anxiety.

The nitrous oxide technique for the semiquantitative measurement of cerebral blood flow devised by Kety and Schmidt (1, 2) has made it desirable to restudy the cerebral circulation in man in various physiologic states. By measuring arterio-internal jugular differences of oxygen and glucose, the relation between changes in cerebral blood flow and cerebral metabolism can be observed. The purpose of this report is to record our findings in the use of the nitrous oxide technique in 33 observations on 20 normal young men; in the comparison of certain cerebral metabolic functions on 14 normal young men in the supine and erect postures; and in observations on the effects of apprehension on the cerebral circulation.

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