A novel technique for cardiopulmonary bypass using vacuum system for venous drainage with pressure relief valve: an experimental study.

To decrease the circuit priming volume, develop safety, and simplify the equipment, a cardiopulmonary bypass (CPB) circuit using a vacuum suction venous drainage system with a pressure relief valve was developed. The efficacy of this vacuum system was compared to that of a conventional siphon system. The system contains a powerful vacuum generator and a pressure relief valve to keep the negative pressure constant when blood suction is used. Using 8 mongrel dogs, the feasibility and the efficacy of this CPB system was tested. The changes in the negative pressure in the reservoir were within 5 mm Hg whether the suction lines were switched on or off. In all animals the amount of blood in the venous reservoir was stable throughout bypass. The decrease of priming volume was from 725 ml (siphon system) to 250 ml (vacuum system). At the end of CPB, the levels of hemoglobin in the vacuum system were significantly higher than those in the siphon system. These results demonstrated that this vacuum drainage system can provide simplification and a miniaturization of the cardiopulmonary bypass circuit resulting in low hemodilution during CPB.

[1]  L. Foubert,et al.  Low extracorporeal priming volumes for infants: a benefit? , 1996, Perfusion.

[2]  A. Galloway,et al.  Minimally invasive cardiopulmonary bypass with cardioplegic arrest: a closed chest technique with equivalent myocardial protection. , 1996, The Journal of thoracic and cardiovascular surgery.

[3]  R. S. Mitchell,et al.  Port-access coronary artery bypass grafting: a proposed surgical method. , 1996, The Journal of thoracic and cardiovascular surgery.

[4]  C. Wildevuur,et al.  Reduction in prime volume attenuates the hyperdynamic response after cardiopulmonary bypass. , 1995, The Annals of thoracic surgery.

[5]  C. Wildevuur,et al.  Clear prime for infant cardiopulmonary bypass: a miniaturized circuit. , 1988, The Journal of cardiovascular surgery.

[6]  E. Garnett,et al.  Albumin and water fluxes during cardiopulmonary bypass. , 1974, The Journal of thoracic and cardiovascular surgery.