Mucorales and Mucormycosis: Recent Insights and Future Prospects
暂无分享,去创建一个
F. Nicolás | V. Garre | J. Cánovas-Márquez | E. Navarro | M. Sanchis | Carlos Lax | Ghizlane Tahiri | Pablo Carrillo-Marín | Eusebio Navarro
[1] R. Würzner,et al. Complement, but Not Platelets, Plays a Pivotal Role in the Outcome of Mucormycosis In Vivo , 2023, Journal of fungi.
[2] S. Kocsubé,et al. cotH Genes Are Necessary for Normal Spore Formation and Virulence in Mucor lusitanicus , 2022, bioRxiv.
[3] G. Santoyo,et al. Secretion of the siderophore rhizoferrin is regulated by the cAMP-PKA pathway and is involved in the virulence of Mucor lusitanicus , 2022, Scientific Reports.
[4] H. Mora-Montes,et al. Mucormycosis and COVID-19-Associated Mucormycosis: Insights of a Deadly but Neglected Mycosis , 2022, Journal of fungi.
[5] F. Nicolás,et al. Genetic Manipulation in Mucorales and New Developments to Study Mucormycosis , 2022, International journal of molecular sciences.
[6] F. Nicolás,et al. Transformation and CRISPR-Cas9-mediated homologous recombination in the fungus Rhizopus microsporus , 2022, STAR protocols.
[7] Xiaoping Zhou,et al. A bacterial endosymbiont of the fungus Rhizopus microsporus drives phagocyte evasion and opportunistic virulence , 2022, Current Biology.
[8] F. Nicolás,et al. Stable and reproducible homologous recombination enables CRISPR-based engineering in the fungus Rhizopus microsporus , 2021, Cell reports methods.
[9] Macario Osorio-Concepción,et al. DNA Methylation on N6-Adenine Regulates the Hyphal Development during Dimorphism in the Early-Diverging Fungus Mucor lusitanicus , 2021, Journal of fungi.
[10] S. Padmanabhan,et al. A ribonuclease III involved in virulence of Mucorales fungi has evolved to cut exclusively single-stranded RNA , 2021, Nucleic acids research.
[11] S. López-García,et al. Role of the Non-Canonical RNAi Pathway in the Antifungal Resistance and Virulence of Mucorales , 2021, Genes.
[12] J. Capilla,et al. A Mucoralean White Collar-1 Photoreceptor Controls Virulence by Regulating an Intricate Gene Network during Host Interactions , 2021, Microorganisms.
[13] F. Nicolás,et al. The RNAi Mechanism Regulates a New Exonuclease Gene Involved in the Virulence of Mucorales , 2021, International journal of molecular sciences.
[14] Soo Chan Lee,et al. The heterotrimeric G-protein beta subunit Gpb1 controls hyphal growth under low oxygen conditions through the protein kinase A pathway and is essential for virulence in the fungus Mucor circinelloides. , 2020, Cellular microbiology.
[15] F. Nicolás,et al. Mucorales Species and Macrophages , 2020, Journal of fungi.
[16] S. Filler,et al. GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis , 2020, mBio.
[17] Macario Osorio-Concepción,et al. Genes, Pathways, and Mechanisms Involved in the Virulence of Mucorales , 2020, Genes.
[18] L. Murcia,et al. A non-canonical RNAi pathway controls virulence and genome stability in Mucorales , 2020, bioRxiv.
[19] P. D. Rogers,et al. Molecular and genetic basis of azole antifungal resistance in the opportunistic pathogenic fungus Candida albicans. , 2019, The Journal of antimicrobial chemotherapy.
[20] J. Heitman,et al. Early Diverging Fungus Mucor circinelloides Lacks Centromeric Histone CENP-A and Displays a Mosaic of Point and Regional Centromeres , 2019, Current Biology.
[21] J. Hodgkin. The model organism diaspora , 2019, Heredity.
[22] D. Stevens,et al. Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis , 2019, Science Advances.
[23] J. Heitman,et al. Drug-Resistant Epimutants Exhibit Organ-Specific Stability and Induction during Murine Infections Caused by the Human Fungal Pathogen Mucor circinelloides , 2019, mBio.
[24] S. Challa. Mucormycosis: Pathogenesis and Pathology , 2019, Current Fungal Infection Reports.
[25] A. Chakrabarti,et al. Global Epidemiology of Mucormycosis , 2019, Journal of fungi.
[26] K. Voigt,et al. Pathogenicity patterns of mucormycosis: epidemiology, interaction with immune cells and virulence factors , 2019, Medical mycology.
[27] J. Heitman,et al. Mucor circinelloides Thrives inside the Phagosome through an Atf-Mediated Germination Pathway , 2019, mBio.
[28] J. Heitman,et al. Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides , 2019, bioRxiv.
[29] R. Wolfe,et al. The epidemiology and clinical manifestations of mucormycosis: a systematic review and meta-analysis of case reports. , 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
[30] E. Corre,et al. Comparative analysis of five Mucor species transcriptomes. , 2019, Genomics.
[31] Ingo Bauer,et al. Generation of A Mucor circinelloides Reporter Strain—A Promising New Tool to Study Antifungal Drug Efficacy and Mucormycosis , 2018, Genes.
[32] M. Hernandez-Oñate,et al. An Adult Zebrafish Model Reveals that Mucormycosis Induces Apoptosis of Infected Macrophages , 2018, Scientific Reports.
[33] J. Wingard,et al. PCR-Based Approach Targeting Mucorales-Specific Gene Family for Diagnosis of Mucormycosis , 2018, Journal of Clinical Microbiology.
[34] Q. Zhang,et al. Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate , 2018, Cell.
[35] J. Capilla,et al. Components of a new gene family of ferroxidases involved in virulence are functionally specialized in fungal dimorphism , 2018, Scientific reports.
[36] Soo Chan Lee,et al. Mucor circinelloides: Growth, Maintenance, and Genetic Manipulation , 2018, Current protocols in microbiology.
[37] J. Guarro,et al. Understanding Mucor circinelloides pathogenesis by comparative genomics and phenotypical studies , 2018, Virulence.
[38] S. López-García,et al. Molecular Tools for Carotenogenesis Analysis in the Mucoral Mucor circinelloides. , 2018, Methods in molecular biology.
[39] Hui Sun,et al. Bacterial endosymbionts influence host sexuality and reveal reproductive genes of early divergent fungi , 2017, Nature Communications.
[40] J. Tyndall,et al. Intrinsic short-tailed azole resistance in mucormycetes is due to an evolutionary conserved aminoacid substitution of the lanosterol 14α-demethylase , 2017, Scientific Reports.
[41] E. Dannaoui. Antifungal resistance in mucorales. , 2017, International journal of antimicrobial agents.
[42] J. Naismith,et al. The rhizoferrin biosynthetic gene in the fungal pathogen Rhizopus delemar is a novel member of the NIS gene family. , 2017, The international journal of biochemistry & cell biology.
[43] J. Heitman,et al. A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides , 2017, PLoS genetics.
[44] J. Capilla,et al. RNAi-Based Functional Genomics Identifies New Virulence Determinants in Mucormycosis , 2017, PLoS pathogens.
[45] G. Goldman,et al. Epidemiological and Genomic Landscape of Azole Resistance Mechanisms in Aspergillus Fungi , 2016, Front. Microbiol..
[46] C. Fraser,et al. An integrated genomic and transcriptomic survey of mucormycosis-causing fungi , 2016, Nature Communications.
[47] G. Garcia-Effron,et al. Aspergillus fumigatus Intrinsic Fluconazole Resistance Is Due to the Naturally Occurring T301I Substitution in Cyp51Ap , 2016, Antimicrobial Agents and Chemotherapy.
[48] Wendy S. Schackwitz,et al. Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication , 2016, Current Biology.
[49] S. Filler,et al. Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis. , 2016, The Journal of clinical investigation.
[50] J. Tyndall,et al. Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase , 2016, Scientific Reports.
[51] J. Dixon,et al. Phosphorylation of spore coat proteins by a family of atypical protein kinases , 2016, Proceedings of the National Academy of Sciences.
[52] V. Narry Kim,et al. Structure of Human DROSHA , 2016, Cell.
[53] H. Riveros-Rosas,et al. Phylogenetic analysis of fungal heterotrimeric G protein-encoding genes and their expression during dimorphism in Mucor circinelloides. , 2015, Fungal biology.
[54] Kerstin Voelz,et al. A zebrafish larval model reveals early tissue-specific innate immune responses to Mucor circinelloides , 2015, Disease Models & Mechanisms.
[55] J. Heitman,et al. Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host–pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides , 2015, Molecular microbiology.
[56] Kylie J. Boyce,et al. Fungal dimorphism: the switch from hyphae to yeast is a specialized morphogenetic adaptation allowing colonization of a host. , 2015, FEMS microbiology reviews.
[57] A. Chowdhary,et al. Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing , 2015, mBio.
[58] T. Chou,et al. Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine , 2015, PLoS pathogens.
[59] S. Moxon,et al. A Non-canonical RNA Silencing Pathway Promotes mRNA Degradation in Basal Fungi , 2015, PLoS genetics.
[60] S. Moxon,et al. The RNAi machinery controls distinct responses to environmental signals in the basal fungus Mucor circinelloides , 2015, BMC Genomics.
[61] D. Kontoyiannis,et al. Iron starvation induces apoptosis in rhizopus oryzae in vitro , 2015, Virulence.
[62] F. Nicolás,et al. Distinct RNAi Pathways in the Regulation of Physiology and Development in the Fungus Mucor circinelloides. , 2015, Advances in genetics.
[63] C. Lass‐Flörl,et al. Susceptibility Profiles of Amphotericin B and Posaconazole against Clinically Relevant Mucorales Species under Hypoxic Conditions , 2014, Antimicrobial Agents and Chemotherapy.
[64] A. Amoresano,et al. Antagonistic Role of CotG and CotH on Spore Germination and Coat Formation in Bacillus subtilis , 2014, PloS one.
[65] Kerstin Voigt,et al. Gene Expansion Shapes Genome Architecture in the Human Pathogen Lichtheimia corymbifera: An Evolutionary Genomics Analysis in the Ancient Terrestrial Mucorales (Mucoromycotina) , 2014, PLoS genetics.
[66] Jian Chen,et al. Efficient transformation of Rhizopus delemar by electroporation of germinated spores. , 2014, Journal of microbiological methods.
[67] Joshua A. Granek,et al. Antifungal drug resistance evokedvia RNAi-dependent epimutations , 2014, Nature.
[68] A. Chowdhary,et al. Exploring azole antifungal drug resistance in Aspergillus fumigatus with special reference to resistance mechanisms. , 2014, Future microbiology.
[69] T. Walsh,et al. Why is mucormycosis more difficult to cure than more common mycoses? , 2014, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
[70] A. Waring,et al. CotH3 mediates fungal invasion of host cells during mucormycosis. , 2014, The Journal of clinical investigation.
[71] N. Costantino,et al. RNase III: Genetics and function; structure and mechanism. , 2013, Annual review of genetics.
[72] J. Heitman,et al. Calcineurin Plays Key Roles in the Dimorphic Transition and Virulence of the Human Pathogenic Zygomycete Mucor circinelloides , 2013, PLoS pathogens.
[73] F. Nicolás,et al. Functional Diversity of RNAi-Associated sRNAs in Fungi , 2013, International journal of molecular sciences.
[74] S. Moxon,et al. A Single Argonaute Gene Participates in Exogenous and Endogenous RNAi and Controls Cellular Functions in the Basal Fungus Mucor circinelloides , 2013, PloS one.
[75] S. Filler,et al. Efficacy of Liposomal Amphotericin B and Posaconazole in Intratracheal Models of Murine Mucormycosis , 2013, Antimicrobial Agents and Chemotherapy.
[76] W. Hansberg,et al. A white collar 1-like protein mediates opposite regulatory functions in Mucor circinelloides. , 2013, Fungal genetics and biology : FG & B.
[77] Peter T. McKenney,et al. The Bacillus subtilis endospore: assembly and functions of the multilayered coat , 2012, Nature Reviews Microbiology.
[78] D. Kontoyiannis,et al. Epidemiology and clinical manifestations of mucormycosis. , 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[79] F. Nicolás,et al. Two distinct RNA‐dependent RNA polymerases are required for initiation and amplification of RNA silencing in the basal fungus Mucor circinelloides , 2012, Molecular microbiology.
[80] S. Brunke,et al. Candida albicans dimorphism as a therapeutic target , 2012, Expert review of anti-infective therapy.
[81] C. Lass‐Flörl. Triazole Antifungal Agents in Invasive Fungal Infections , 2011, Drugs.
[82] J. Meis,et al. Antifungal Susceptibility and Phylogeny of Opportunistic Members of the Order Mucorales , 2011, Journal of Clinical Microbiology.
[83] A. Gutierrez,et al. High reliability transformation of the basal fungus Mucor circinelloides by electroporation. , 2011, Journal of microbiological methods.
[84] Lin Lin,et al. The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis , 2010, Molecular microbiology.
[85] V. Moulton,et al. Endogenous short RNAs generated by Dicer 2 and RNA-dependent RNA polymerase 1 regulate mRNAs in the basal fungus Mucor circinelloides , 2010, Nucleic acids research.
[86] W. Melchers,et al. Azole Resistance Profile of Amino Acid Changes in Aspergillus fumigatus CYP51A Based on Protein Homology Modeling , 2010, Antimicrobial Agents and Chemotherapy.
[87] F. Nicolás,et al. A Single dicer Gene Is Required for Efficient Gene Silencing Associated with Two Classes of Small Antisense RNAs in Mucor circinelloides , 2009, Eukaryotic Cell.
[88] Ashraf S. Ibrahim,et al. Genomic Analysis of the Basal Lineage Fungus Rhizopus oryzae Reveals a Whole-Genome Duplication , 2009, PLoS genetics.
[89] F. Nicolás,et al. Transcriptional activation increases RNA silencing efficiency and stability in the fungus Mucor circinelloides. , 2009, Journal of biotechnology.
[90] V. Garre,et al. A Subunit of Protein Kinase A Regulates Growth and Differentiation in the Fungus Mucor circinelloides , 2009, Eukaryotic Cell.
[91] V. Garre,et al. A RING‐finger protein regulates carotenogenesis via proteolysis‐independent ubiquitylation of a White Collar‐1‐like activator , 2008, Molecular microbiology.
[92] F. Nicolás,et al. A RING-finger photocarotenogenic repressor involved in asexual sporulation in Mucor circinelloides. , 2008, FEMS microbiology letters.
[93] R. Ruiz-Vazquez,et al. Lycopene over-accumulation by disruption of the negative regulator gene crgA in Mucor circinelloides , 2008, Applied Microbiology and Biotechnology.
[94] D. Court,et al. A stepwise model for double‐stranded RNA processing by ribonuclease III , 2007, Molecular microbiology.
[95] F. Nicolás,et al. Mutants defective in a Mucor circinelloides dicer-like gene are not compromised in siRNA silencing but display developmental defects. , 2007, Fungal genetics and biology : FG & B.
[96] V. Garre,et al. Distinct white collar‐1 genes control specific light responses in Mucor circinelloides , 2006, Molecular microbiology.
[97] J. Perfect,et al. Zygomycosis: the re-emerging fungal infection , 2006, European Journal of Clinical Microbiology and Infectious Diseases.
[98] H. Rogers,et al. Natural resistance, iron and infection: a challenge for clinical medicine. , 2006, Journal of medical microbiology.
[99] A. Chakrabarti,et al. Mucormycosis in immunocompetent individuals: an increasing trend. , 2005, The Journal of otolaryngology.
[100] C. Hertweck,et al. Pathogenic fungus harbours endosymbiotic bacteria for toxin production , 2005, Nature.
[101] E. Mellado,et al. A Point Mutation in the 14α-Sterol Demethylase Gene cyp51A Contributes to Itraconazole Resistance in Aspergillus fumigatus , 2004, Antimicrobial Agents and Chemotherapy.
[102] M. Roncero,et al. Transformation of a methionine auxotrophic mutant of Mucor circinelloides by direct cloning of the corresponding wild type gene , 1991, Molecular and General Genetics MGG.
[103] F. Nicolás,et al. Two classes of small antisense RNAs in fungal RNA silencing triggered by non‐integrative transgenes , 2003, The EMBO journal.
[104] H. Haas. Molecular genetics of fungal siderophore biosynthesis and uptake: the role of siderophores in iron uptake and storage , 2003, Applied Microbiology and Biotechnology.
[105] E. Mellado,et al. A Point Mutation in the 14α-Sterol Demethylase Gene cyp51A Contributes to Itraconazole Resistance in Aspergillus fumigatus , 2003, Antimicrobial Agents and Chemotherapy.
[106] A. Glasmacher,et al. Clinical pharmacology of antifungal compounds. , 2003, Infectious disease clinics of North America.
[107] J. Arnau,et al. Identification and analysis of genes involved in the control of dimorphism in Mucor circinelloides (syn. racemosus). , 2002, FEMS yeast research.
[108] F. Nicolás,et al. A negative regulator of light-inducible carotenogenesis in Mucor circinelloides , 2001, Zeitschrift für Induktive Abstammungs- und Vererbungslehre.
[109] A. Thieken,et al. Rhizoferrin: a complexone type siderophore of the Mucorales and entomophthorales (Zygomycetes). , 1992, FEMS microbiology letters.
[110] M. Orlowski. Mucor dimorphism , 1991 .
[111] S. Kelly,et al. Defective sterol C5-6 desaturation and azole resistance: a new hypothesis for the mode of action of azole antifungals. , 1989, Biochemical and biophysical research communications.
[112] M. Roncero,et al. High frequency transformation of Mucor with recombinant plasmid DNA , 1984 .
[113] M. Roncero. Enrichment method for the isolation of auxotrophic mutants of Mucor using the polyene antibiotic N-glycosyl-polifungin , 1984 .