Optimizing the fragment complementation of APEX2 for detection of specific protein-protein interactions in live cells

[1]  T. Deerinck,et al.  A split horseradish peroxidase for detection of intercellular protein-protein interactions and sensitive visualization of synapses , 2016, Nature Biotechnology.

[2]  Liangyi Chen,et al.  Proteomic mapping of ER-PM junctions identifies STIMATE as regulator of Ca2+ influx , 2015, Nature Cell Biology.

[3]  Shenyuan L. Zhang,et al.  Inside-out Ca2+ signalling prompted by STIM1 conformational switch , 2015, Nature Communications.

[4]  E. Isacoff,et al.  Critical role for Orai1 C-terminal domain and TM4 in CRAC channel gating , 2015, Cell Research.

[5]  K. Lilley,et al.  Selective Proteomic Proximity Labeling Assay Using Tyramide (SPPLAT): A Quantitative Method for the Proteomic Analysis of Localized Membrane‐Bound Protein Clusters , 2015, Current protocols in protein science.

[6]  Mark H. Ellisman,et al.  Supplementary Text: Mechanistic Investigation of Apex2 , 2014 .

[7]  R. Murrell-Lagnado,et al.  Atomic force microscopy (AFM) imaging suggests that stromal interaction molecule 1 (STIM1) binds to Orai1 with sixfold symmetry , 2014, FEBS letters.

[8]  S. Carr,et al.  Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging. , 2014, Molecular cell.

[9]  K. Lilley,et al.  New Insights into the DT40 B Cell Receptor Cluster Using a Proteomic Proximity Labeling Assay , 2014, The Journal of Biological Chemistry.

[10]  C. Romanin,et al.  STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry , 2013, Nature Communications.

[11]  S. Carr,et al.  Proteomic Mapping of Mitochondria in Living Cells via Spatially Restricted Enzymatic Tagging , 2013, Science.

[12]  S. Long,et al.  Crystal Structure of the Calcium Release–Activated Calcium Channel Orai , 2012, Science.

[13]  Mark H. Ellisman,et al.  Engineered ascorbate peroxidase as a genetically-encoded reporter for electron microscopy , 2012, Nature Biotechnology.

[14]  X. Yang,et al.  Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1) , 2012, Proceedings of the National Academy of Sciences.

[15]  P. Várnai,et al.  Activation of STIM1-Orai1 Involves an Intramolecular Switching Mechanism , 2010, Science Signaling.

[16]  Jianli Li,et al.  Membrane Targeted Horseradish Peroxidase as a Marker for Correlative Fluorescence and Electron Microscopy Studies , 2009, Front. Neural Circuits.

[17]  Shaomeng Wang,et al.  Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy. , 2009, Annual review of pharmacology and toxicology.

[18]  David Warde-Farley,et al.  Dynamic modularity in protein interaction networks predicts breast cancer outcome , 2009, Nature Biotechnology.

[19]  Shenyuan L. Zhang,et al.  The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers , 2008, Nature.

[20]  Cori Bargmann,et al.  GFP Reconstitution Across Synaptic Partners (GRASP) Defines Cell Contacts and Synapses in Living Nervous Systems , 2008, Neuron.

[21]  Stephen W. Michnick,et al.  Universal strategies in research and drug discovery based on protein-fragment complementation assays , 2007, Nature Reviews Drug Discovery.

[22]  JoAnn Buchanan,et al.  Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane , 2006, The Journal of cell biology.

[23]  Andrea Sinz,et al.  Chemical cross-linking and mass spectrometry to map three-dimensional protein structures and protein-protein interactions. , 2006, Mass spectrometry reviews.

[24]  H. Piwnica-Worms,et al.  Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[25]  M. Mewies,et al.  Crystal structure of the ascorbate peroxidase–ascorbate complex , 2003, Nature Structural Biology.

[26]  E. Golemis,et al.  Using the yeast interaction trap and other two-hybrid-based approaches to study protein-protein interactions. , 2001, Methods.

[27]  C. Kahn,et al.  Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. , 1999, The Journal of clinical investigation.

[28]  A. Chapman-Smith,et al.  Molecular biology of biotin attachment to proteins. , 1999, The Journal of nutrition.

[29]  F. Rosell,et al.  Class I heme peroxidases: characterization of soybean ascorbate peroxidase. , 1998, Archives of biochemistry and biophysics.

[30]  Stuart L. Schreiber,et al.  Structure of the FKBP12-Rapamycin Complex Interacting with Binding Domain of Human FRAP , 1996, Science.

[31]  T. Poulos,et al.  Crystal structure of recombinant pea cytosolic ascorbate peroxidase. , 1995, Biochemistry.

[32]  C. Futter,et al.  Transport into and out of the Golgi complex studied by transfecting cells with cDNAs encoding horseradish peroxidase , 1994, The Journal of cell biology.

[33]  D. Pollen,et al.  Alzheimer's disease and possible gene interaction. , 1994, Science.

[34]  K. Fluiter,et al.  A novel approach to cancer therapy , 2007 .

[35]  Gary D Luker,et al.  Visualizing protein-protein interactions in living animals. , 2003, Methods.