A mathematical model of the Bloch NMR equations for quantitative analysis of blood flow in blood vessels with changing cross-section-I

Recently, magnetic resonance imaging has moved away from merely depicting the morphology of objects or disease states and is now concerned with creating spatially localized representations of dynamics and function. Dynamical measurements of blood flow, is one example of this trend. Improving these techniques requires an understanding of the basic physics that govern imaging technology and the functions of biological systems. This presentation is focused on mathematical modeling of the Bloch NMR flow equations into Bessel functions of the first and the second kind. The model is tailored towards understanding the basic physics of extracting the relevant flow parameters by which velocity quantification can be made in blood vessels with changing cross-section to solve real problems in medicine and biology.

[1]  P Boesiger,et al.  FID-acquired-echos (FAcE): a short echo time imaging method for flow artefact suppression. , 1991, Magnetic resonance imaging.

[2]  O Henriksen,et al.  Quantification of complex flow using MR phase imaging--a study of parameters influencing the phase/velocity relation. , 1992, Magnetic resonance imaging.

[3]  P Boesiger,et al.  Visualization and quantification of the human blood flow by magnetic resonance imaging. , 1992, Journal of biomechanics.

[4]  M Kouwenhoven,et al.  Motion Induced Phase Shifts in MR: Acceleration Effects in Quantitative Flow Measurements—A Reconsideration , 1995, Magnetic resonance in medicine.

[5]  D Meier,et al.  Quantitative flow measurements on phantoms and on blood vessels with MR , 1988, Magnetic resonance in medicine.

[6]  C. Slichter Principles of magnetic resonance , 1963 .

[7]  D N Firmin,et al.  Blood flow imaging by cine magnetic resonance. , 1986, Journal of computer assisted tomography.

[8]  D N Firmin,et al.  The application of phase shifts in NMR for flow measurement , 1990, Magnetic resonance in medicine.

[9]  O. Simonetti,et al.  Experimental confirmation of phase encoding of instantaneous derivatives of position , 1994, Magnetic resonance in medicine.

[10]  R. Pettigrew,et al.  Effects of acceleration on the accuracy of MR phase velocity measurements , 1992, Journal of magnetic resonance imaging : JMRI.

[11]  Nuclear magnetic resonance velocity spectra of pulsatile flow in a rigid tube , 1992, Magnetic resonance in medicine.

[12]  N J Pelc,et al.  Volume MR angiography: methods to achieve very short echo times. , 1990, Radiology.

[13]  René M. Botnar,et al.  Quantification of blood flow patterns in human vessels by magnetic resonance imaging. , 1996, Technology and health care : official journal of the European Society for Engineering and Medicine.

[14]  A. Fenster,et al.  Computer‐controlled flow simulator for MR flow studies , 1992, Journal of magnetic resonance imaging : JMRI.

[15]  D N Firmin,et al.  Valve and great vessel stenosis: assessment with MR jet velocity mapping. , 1991, Radiology.

[16]  N J Pelc,et al.  Minimizing TE in moment‐nulled or flow‐encoded two‐and three‐dimensional gradient‐echo imaging , 1992, Journal of magnetic resonance imaging : JMRI.