Systematic review and meta‐analysis: D‐Penicillamine vs. placebo/no intervention in patients with primary biliary cirrhosis – Cochrane Hepato‐Biliary Group

Background  d‐Penicillamine is used for patients with primary biliary cirrhosis due to its ability to decrease hepatic copper and modulate the immune response. The results on effects of d‐‐penicillamine in randomized‐clinical trials of primary biliary cirrhosis patients are inconsistent.

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