Decreased Prefrontal Myo-Inositol in Major Depressive Disorder

[1]  P. Sundgren,et al.  Magnetic resonance spectroscopy. , 2005, Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.

[2]  G. Rajkowska,et al.  Age-Dependent Reductions in the Level of Glial Fibrillary Acidic Protein in the Prefrontal Cortex in Major Depression , 2004, Neuropsychopharmacology.

[3]  M. Keshavan,et al.  1H MRS Study of Dorsolateral Prefrontal Cortex in Healthy Individuals before and after Lithium Administration , 2004, Neuropsychopharmacology.

[4]  John H Krystal,et al.  Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression. , 2004, Archives of general psychiatry.

[5]  J. Greer,et al.  Phosphoinositide deficiency due to inositol depletion is not a mechanism of lithium action in brain. , 2004, Molecular genetics and metabolism.

[6]  Napapon Sailasuta,et al.  A comparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D 1H proton spectroscopic imaging of the human brain. , 2004, Magnetic resonance imaging.

[7]  Michael Marriott,et al.  Lower hippocampal volume in patients suffering from depression: a meta-analysis. , 2004, The American journal of psychiatry.

[8]  N. Uranova,et al.  Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley Neuropathology Consortium , 2004, Schizophrenia Research.

[9]  J. Price,et al.  Glial reduction in amygdala in major depressive disorder is due to oligodendrocytes , 2004, Biological Psychiatry.

[10]  P. Allen,et al.  Strategy for the spectral filtering of myo‐inositol and other strongly coupled spins , 2004, Magnetic resonance in medicine.

[11]  Richard Robitaille,et al.  Glial Cells and Neurotransmission An Inclusive View of Synaptic Function , 2003, Neuron.

[12]  J. Schölmerich,et al.  Alterations of cerebral metabolism in patients with diabetes mellitus studied by proton magnetic resonance spectroscopy. , 2003, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

[13]  Meena Vythilingam,et al.  Focal and lateralized subcortical abnormalities in unipolar major depressive disorder: an automated multivoxel proton magnetic resonance spectroscopy study , 2003, Biological Psychiatry.

[14]  J. Gorman,et al.  A magnetic resonance spectroscopic imaging study of adult nonhuman primates exposed to early-life stressors , 2003, Biological Psychiatry.

[15]  V. Arolt,et al.  Metabolic changes within the left dorsolateral prefrontal cortex occurring with electroconvulsive therapy in patients with treatment resistant unipolar depression , 2003, Psychological Medicine.

[16]  J. McCracken,et al.  Proton magnetic resonance spectroscopy of bipolar disorder versus intermittent explosive disorder in children and adolescents. , 2003, The American journal of psychiatry.

[17]  Y. Sheline Neuroimaging studies of mood disorder effects on the brain , 2003, Biological Psychiatry.

[18]  A. Harwood Neurodevelopment and mood stabilizers. , 2003, Current molecular medicine.

[19]  G. Kemp,et al.  Quantification of Metabolic Differences in the Frontal Brain of Depressive Patients and Controls Obtained by 1H-MRS at 3 Tesla , 2003, Investigative radiology.

[20]  Morris H. Baslow,et al.  N-Acetylaspartate in the Vertebrate Brain: Metabolism and Function , 2003, Neurochemical Research.

[21]  Cheuk Y. Tang,et al.  A multi‐center 1H MRS study of the AIDS dementia complex: Validation and preliminary analysis , 2003, Journal of magnetic resonance imaging : JMRI.

[22]  Lisa A. Thomas,et al.  Biologic findings of post-traumatic stress disorder and child maltreatment , 2003, Current psychiatry reports.

[23]  C. Jack,et al.  Proton MR spectroscopy in mild cognitive impairment and Alzheimer disease: comparison of 1.5 and 3 T. , 2003, AJNR. American journal of neuroradiology.

[24]  Robert Bartha,et al.  Quantitative proton short‐echo‐time LASER spectroscopy of normal human white matter and hippocampus at 4 Tesla incorporating macromolecule subtraction , 2003, Magnetic resonance in medicine.

[25]  V. Arolt,et al.  Neurotrophic Effects of Electroconvulsive Therapy: A Proton Magnetic Resonance Study of the Left Amygdalar Region in Patients with Treatment-Resistant Depression , 2003, Neuropsychopharmacology.

[26]  Martin Fiebich,et al.  Effective electroconvulsive therapy reverses glutamate/glutamine deficit in the left anterior cingulum of unipolar depressed patients , 2003, Psychiatry Research: Neuroimaging.

[27]  Martin H. Teicher,et al.  The neurobiological consequences of early stress and childhood maltreatment , 2003, Neuroscience & Biobehavioral Reviews.

[28]  Eric Vermetten,et al.  Childhood trauma associated with smaller hippocampal volume in women with major depression. , 2002, The American journal of psychiatry.

[29]  J. O'Brien,et al.  Glial fibrillary acidic protein in late life major depressive disorder: an immunocytochemical study , 2002, Journal of neurology, neurosurgery, and psychiatry.

[30]  R. Barber,et al.  Pathologies and Pathological Mechanisms for White Matter Hyperintensities in Depression , 2002, Annals of the New York Academy of Sciences.

[31]  Kishore Bhakoo,et al.  Spectral profiles of cultured neuronal and glial cells derived from HRMAS 1H NMR spectroscopy , 2002, NMR in biomedicine.

[32]  G. Rajkowska Cell pathology in mood disorders. , 2002, Seminars in clinical neuropsychiatry.

[33]  C. Hanstock,et al.  GABA X2 multiplet measured pre‐ and post‐administration of vigabatrin in human brain , 2002, Magnetic resonance in medicine.

[34]  J. Price,et al.  Low glial numbers in the amygdala in major depressive disorder , 2002, Biological Psychiatry.

[35]  D. Rosenberg,et al.  Proton magnetic resonance spectroscopic imaging in pediatric major depression , 2002, Biological Psychiatry.

[36]  Paul J. Harrison,et al.  The neuropathology of primary mood disorder. , 2002, Brain : a journal of neurology.

[37]  Kenneth S Kendler,et al.  Toward a comprehensive developmental model for major depression in men. , 2006, The American journal of psychiatry.

[38]  Jim Mintz,et al.  Frontal white matter biochemical abnormalities in late-life major depression detected with proton magnetic resonance spectroscopy. , 2002, The American journal of psychiatry.

[39]  Sabine Landau,et al.  Reduced neuronal size and glial cell density in area 9 of the dorsolateral prefrontal cortex in subjects with major depressive disorder. , 2002, Cerebral cortex.

[40]  P. Renshaw,et al.  Magnetic resonance spectroscopy: current and future applications in psychiatric research , 2002, Biological Psychiatry.

[41]  Yogesh K. Dwivedi,et al.  Hyperactive phosphoinositide signaling pathway in platelets of depressed patients: effect of desipramine treatment , 2001, Psychiatry Research.

[42]  L. Gates,et al.  Left Medial Temporal Cytosolic Choline in Early Onset Depression , 2001, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[43]  C Boesch,et al.  Characterization of the macromolecule baseline in localized 1H‐MR spectra of human brain , 2001, Magnetic resonance in medicine.

[44]  M. Bohus,et al.  Subtle prefrontal neuropathology in a pilot magnetic resonance spectroscopy study in patients with borderline personality disorder. , 2001, The Journal of neuropsychiatry and clinical neurosciences.

[45]  P. Hof,et al.  Anterior cingulate cortex pathology in schizophrenia and bipolar disorder , 2001, Acta Neuropathologica.

[46]  G B Matson,et al.  Short echo time multislice proton magnetic resonance spectroscopic imaging in human brain: metabolite distributions and reliability. , 2001, Magnetic resonance imaging.

[47]  E. Vermetten,et al.  Stress and development: Behavioral and biological consequences , 2001, Development and Psychopathology.

[48]  R. Saunders,et al.  A quantitative immunohistochemical study of astrocytes in the entorhinal cortex in schizophrenia, bipolar disorder and major depression: absence of significant astrocytosis , 2001, Brain Research Bulletin.

[49]  N Roberts,et al.  A proton magnetic resonance spectroscopy study of age-related changes in frontal lobe metabolite concentrations. , 2001, Cerebral cortex.

[50]  R. Kerwin,et al.  Reduced glial cell density and neuronal size in the anterior cingulate cortex in major depressive disorder. , 2001, Archives of general psychiatry.

[51]  J. McCracken,et al.  Decreased Anterior Cingulate Myo-inositol/Creatine Spectroscopy Resonance with Lithium Treatment in Children with Bipolar Disorder , 2001, Neuropsychopharmacology.

[52]  P. Renshaw,et al.  Increased orbitofrontal cortex levels of choline in depressed adolescents as detected by in vivo proton magnetic resonance spectroscopy , 2000, Biological Psychiatry.

[53]  G. Rajkowska,et al.  Glial fibrillary acidic protein immunoreactivity in the prefrontal cortex distinguishes younger from older adults in major depressive disorder , 2000, Biological Psychiatry.

[54]  D. Braus,et al.  The hippocampus in patients treated with electroconvulsive therapy: a proton magnetic resonance spectroscopic imaging study. , 2000, Archives of general psychiatry.

[55]  M. Wolfson,et al.  A Model of Inositol Compartmentation in Astrocytes Based Upon Efflux Kinetics and Slow Inositol Depletion after Uptake Inhibition , 2000, Neurochemical Research.

[56]  M. Wolfson,et al.  Nordidemnin potently inhibits inositol uptake in cultured astrocytes and dose‐dependently augments lithium's proconvulsant effect in vivo , 2000, Journal of neuroscience research.

[57]  Bernadette Lipinski,et al.  Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study , 2000, Biological Psychiatry.

[58]  C. Hanstock,et al.  Effects of lithium and amphetamine on inositol metabolism in the human brain as measured by 1H and 31P MRS , 1999, Biological Psychiatry.

[59]  J. Parrish,et al.  Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness. , 1999, The American journal of psychiatry.

[60]  J. Frahm,et al.  Inflammatory CNS demyelination: histopathologic correlation with in vivo quantitative proton MR spectroscopy. , 1999, AJNR. American journal of neuroradiology.

[61]  B. Roth,et al.  Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression∗ ∗ See accompanying Editorial, in this issue. , 1999, Biological Psychiatry.

[62]  K O Lim,et al.  In vivo spectroscopic quantification of the N‐acetyl moiety, creatine, and choline from large volumes of brain gray and white matter: Effects of normal aging , 1999, Magnetic resonance in medicine.

[63]  J. Price,et al.  Glial reduction in the subgenual prefrontal cortex in mood disorders. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[64]  R. Belmaker,et al.  Cerebrospinal fluid inositol monophosphatase: elevated activity in depression and neuroleptic-treated schizophrenia , 1998, Biological Psychiatry.

[65]  R. Frey,et al.  Myo-inositol in depressive and healthy subjects determined by frontal 1H-magnetic resonance spectroscopy at 1.5 tesla. , 1998, Journal of psychiatric research.

[66]  J. Kleinman,et al.  Reduced frontal cortex inositol levels in postmortem brain of suicide victims and patients with bipolar disorder. , 1997, The American journal of psychiatry.

[67]  J. Gaillard,et al.  Platelet phosphoinositide signaling system: an overstimulated pathway in depression , 1996, Biological Psychiatry.

[68]  H C Charles,et al.  Reproducibility of high spatial resolution proton magnetic resonance spectroscopic imaging in the human brain , 1996, Magnetic resonance in medicine.

[69]  T W Redpath,et al.  Technical note: use of a double inversion recovery pulse sequence to image selectively grey or white brain matter. , 1994, The British journal of radiology.

[70]  K. Behar,et al.  Analysis of macromolecule resonances in 1H NMR spectra of human brain , 1994, Magnetic resonance in medicine.

[71]  S. Provencher Estimation of metabolite concentrations from localized in vivo proton NMR spectra , 1993, Magnetic resonance in medicine.

[72]  R Gruetter,et al.  Automatic, localized in Vivo adjustment of all first‐and second‐order shim coils , 1993, Magnetic resonance in medicine.

[73]  R. Hales,et al.  J Neuropsychiatry Clin Neurosci , 1992 .

[74]  M. Berridge Inositol Trisphosphate, Calcium, Lithium, and Cell Signaling , 1989 .

[75]  K Berry,et al.  FREE AMINO ACIDS AND RELATED COMPOUNDS IN BIOPSIES OF HUMAN BRAIN , 1971, Journal of neurochemistry.

[76]  R. Duman,et al.  Role of neurotrophic factors in the etiology and treatment of mood disorders , 2007, NeuroMolecular Medicine.

[77]  Kim M Cecil,et al.  Proton magnetic resonance spectroscopy of the frontal lobe and cerebellar vermis in children with a mood disorder and a familial risk for bipolar disorders. , 2003, Journal of child and adolescent psychopharmacology.

[78]  G. Moore,et al.  Magnetic resonance spectroscopy: neurochemistry and treatment effects in affective disorders. , 2002, Psychopharmacology bulletin.

[79]  G. Rajkowska,et al.  Histopathology of the prefrontal cortex in major depression: what does it tell us about dysfunctional monoaminergic circuits? , 2000, Progress in brain research.