Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation
暂无分享,去创建一个
S. Eyre | J. Mclaughlin | A. Brass | W. Ollier | P. Fisher | R. Grencis | L. Zeef | J. Pennock | S. Levison | J. Hankinson
[1] S. Eyre,et al. Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation , 2013, BMC Genomics.
[2] W. Garrett,et al. Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus , 2011, Proceedings of the National Academy of Sciences.
[3] J. Mclaughlin,et al. Colonic transcriptional profiling in resistance and susceptibility to trichuriasis: Phenotyping a chronic colitis and lessons for iatrogenic helminthosis , 2010, Inflammatory bowel diseases.
[4] C. Wijmenga,et al. Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations† , 2010, Inflammatory bowel diseases.
[5] T. Macdonald,et al. IL‐23/IL‐17 axis in IBD , 2010, Inflammatory bowel diseases.
[6] C. Farber,et al. Serious limitations of the QTL/Microarray approach for QTL gene discovery , 2010, BMC Biology.
[7] J. Affourtit,et al. Cdcs1 a major colitis susceptibility locus in mice; Subcongenic analysis reveals genetic complexity , 2010, Inflammatory bowel diseases.
[8] H. Noyes,et al. Heligmosomoides bakeri: a model for exploring the biology and genetics of resistance to chronic gastrointestinal nematode infections , 2009, Parasitology.
[9] I. Cattadori,et al. Genetic variation in resistance to mixed, predominantly Teladorsagia circumcincta nematode infections of sheep: from heritabilities to gene identification , 2009, Parasite immunology.
[10] W. Swat,et al. Vav proteins are necessary for correct differentiation of mouse cecal and colonic enterocytes , 2009, Journal of Cell Science.
[11] R. Nurieva,et al. Regulation and Function of Proinflammatory TH17 Cells , 2008, Annals of the New York Academy of Sciences.
[12] Judy H. Cho,et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease , 2008, Nature Genetics.
[13] R. Grencis,et al. The intestinal epithelium: sensors to effectors in nematode infection , 2008, Mucosal Immunology.
[14] M. McCarthy,et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges , 2008, Nature Reviews Genetics.
[15] G. Churchill,et al. Applying Gene Expression, Proteomics and Single-Nucleotide Polymorphism Analysis for Complex Trait Gene Identification , 2008, Genetics.
[16] Robert Stevens,et al. A systematic strategy for large-scale analysis of genotype–phenotype correlations: identification of candidate genes involved in African trypanosomiasis , 2007, Nucleic acids research.
[17] Simon C. Potter,et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.
[18] Y H Lee,et al. The PTPN22 C1858T functional polymorphism and autoimmune diseases--a meta-analysis. , 2007, Rheumatology.
[19] D. Littman,et al. The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells , 2006, Cell.
[20] F. Iraqi,et al. High resolution mapping of chromosomal regions controlling resistance to gastrointestinal nematode infections in an advanced intercross line of mice , 2006, Mammalian Genome.
[21] Tohru Suzuki,et al. Chromosomal mapping of host resistance loci to Trichinella spiralis nematode infection in rats , 2006, Immunogenetics.
[22] J. Sundberg,et al. Cdcs1, a major colitogenic locus in mice, regulates innate and adaptive immune response to enteric bacterial antigens. , 2005, Gastroenterology.
[23] K. Siminovitch,et al. Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations. , 2005, Arthritis and rheumatism.
[24] V. Tybulewicz,et al. Vav-family proteins in T-cell signalling. , 2005, Current opinion in immunology.
[25] William Valdar,et al. Strategies for mapping and cloning quantitative trait genes in rodents , 2005, Nature Reviews Genetics.
[26] A. Peña,et al. A major quantitative trait locus on mouse chromosome 3 is involved in disease susceptibility in different colitis models. , 2005, Gastroenterology.
[27] S. Dominik. Quantitative trait loci for internal nematode resistance in sheep: a review , 2005, Genetics Selection Evolution.
[28] Steven J. Schrodi,et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. , 2004, American journal of human genetics.
[29] Nunzio Bottini,et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes , 2004, Nature Genetics.
[30] R. Grencis,et al. The Trichuris muris system: a paradigm of resistance and susceptibility to intestinal nematode infection. , 2004, Advances in parasitology.
[31] S. Awasthi,et al. Helminthic infections , 2003, BMJ : British Medical Journal.
[32] C. Moskaluk,et al. Identification of a quantitative trait locus for ileitis in a spontaneous mouse model of Crohn's disease: SAMP1/YitFc. , 2003, Gastroenterology.
[33] Karl W Broman,et al. Mapping quantitative trait loci in the case of a spike in the phenotype distribution. , 2003, Genetics.
[34] Jens Holmberg,et al. Positional identification of Ncf1 as a gene that regulates arthritis severity in rats , 2003, Nature Genetics.
[35] J. Nadeau,et al. Finding Genes That Underlie Complex Traits , 2002, Science.
[36] J. Maddox,et al. A genome scan for quantitative trait loci affecting resistance to Trichostrongylus colubriformis in sheep. , 2002, Animal genetics.
[37] G. van Ommen,et al. FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. , 2002, Immunity.
[38] J. Sundberg,et al. A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[39] John D. Welsh,et al. Vav3 Mediates Receptor Protein Tyrosine Kinase Signaling, Regulates GTPase Activity, Modulates Cell Morphology, and Induces Cell Transformation , 2000, Molecular and Cellular Biology.
[40] C. Elson,et al. Heritable Susceptibility for Colitis in Mice Induced by IL‐10 Deficiency , 2000, Inflammatory bowel diseases.
[41] Susumu Goto,et al. KEGG: Kyoto Encyclopedia of Genes and Genomes , 2000, Nucleic Acids Res..
[42] R. Grencis,et al. A critical role for IL-13 in resistance to intestinal nematode infection. , 1998, Journal of immunology.
[43] E. Lander,et al. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results , 1995, Nature Genetics.
[44] F. Finkelman,et al. Cytokine-mediated regulation of chronic intestinal helminth infection , 1994, The Journal of experimental medicine.
[45] K. Else,et al. Correlations between worm burden and markers of Th1 and Th2 cell subset induction in an inbred strain of mouse infected with Trichuris muris , 1993, Parasite immunology.
[46] D. Wakelin. Acquired immunity to Trichuris muris in the albino laboratory mouse , 1967, Parasitology.