ADD-ASPIRIN: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non-metastatic solid tumours
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D. Cameron | A. Ring | H. Kynaston | C. Pramesh | Sudeep Gupta | M. Mackenzie | R. Langley | F. Cafferty | S. Rowley | R. Wilson | D. Gilbert | C. Coyle | R. Wilson | L. Berkman
[1] E. Whitlock,et al. Bleeding Risks With Aspirin Use for Primary Prevention in Adults: A Systematic Review for the U.S. Preventive Services Task Force , 2016, Annals of Internal Medicine.
[2] P. Elwood,et al. Aspirin in the Treatment of Cancer: Reductions in Metastatic Spread and in Mortality: A Systematic Review and Meta-Analyses of Published Studies , 2016, PloS one.
[3] C. V. D. van de Velde,et al. The effect of aspirin and nonsteroidal anti-inflammatory drug use after diagnosis on survival of oesophageal cancer patients , 2016, British Journal of Cancer.
[4] T. Kim,et al. The effect of prediagnostic aspirin use on the prognosis of stage III colorectal cancer. , 2015, International journal of clinical and experimental medicine.
[5] B. Møller,et al. Impact of aspirin as secondary prevention in an unselected cohort of 25,644 patients with colorectal cancer: A population-based study. , 2015 .
[6] S. Zhong,et al. Association between aspirin use and mortality in breast cancer patients: a meta-analysis of observational studies , 2015, Breast Cancer Research and Treatment.
[7] S. Ozawa,et al. Impact of preoperative neutrophil to lymphocyte ratio on long-term survival in patients with esophageal squamous cell carcinoma. , 2015 .
[8] N. Cook,et al. Estimates of benefits and harms of prophylactic use of aspirin in the general population , 2014, Annals of oncology : official journal of the European Society for Medical Oncology.
[9] J. Meyerhardt,et al. Aspirin and COX-2 inhibitor use in patients with stage III colon cancer. , 2015, Journal of the National Cancer Institute.
[10] S. Freedland,et al. Daily aspirin use and prostate cancer-specific mortality in a large cohort of men with nonmetastatic prostate cancer. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[11] P. Royston,et al. An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect , 2014, Trials.
[12] C. McCowan,et al. Aspirin use and survival after the diagnosis of breast cancer: a population-based cohort study , 2014, British Journal of Cancer.
[13] D. Kerr,et al. Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[14] N. Cook,et al. Alternate-Day, Low-Dose Aspirin and Cancer Risk: Long-Term Observational Follow-up of a Randomized Trial , 2013, Annals of Internal Medicine.
[15] R. Jorissen,et al. Aspirin use and survival outcomes in patients (pts) with PIK3CA mutant colorectal cancer (CRC). , 2013 .
[16] T. Yeatman,et al. Association of aspirin use with improved 5-year survival in colorectal cancer patients with PIK3CA mutation. , 2013 .
[17] P. Donnan,et al. Use of aspirin post-diagnosis in a cohort of patients with colorectal cancer and its association with all-cause and colorectal cancer specific mortality. , 2013, European journal of cancer.
[18] D. Bishop,et al. Edinburgh Research Explorer Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer , 2022 .
[19] Reiko Nishihara,et al. Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. , 2012, The New England journal of medicine.
[20] Sujoy Ghosh,et al. Prostate Cancer, Androgen Deprivation Therapy, Obesity, the Metabolic Syndrome, Type 2 Diabetes, and Cardiovascular Disease: A Review , 2012, American journal of clinical oncology.
[21] A. Walker,et al. Aspirin and other non-steroidal anti-inflammatory drug use and colorectal cancer survival: a cohort study , 2012, British Journal of Cancer.
[22] E. Horwitz,et al. Aspirin and statin nonuse associated with early biochemical failure after prostate radiation therapy. , 2012, International journal of radiation oncology, biology, physics.
[23] Anthony V D'Amico,et al. Aspirin use and the risk of prostate cancer mortality in men treated with prostatectomy or radiotherapy. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[24] J. Cuzick,et al. Aspirin and cancer risk: a quantitative review to 2011. , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.
[25] M. Parmar,et al. Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial , 2012, The Lancet. Oncology.
[26] P. Rothwell,et al. Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials. , 2012, The Lancet. Oncology.
[27] M. Thun,et al. The role of aspirin in cancer prevention , 2012, Nature Reviews Clinical Oncology.
[28] P. Rothwell,et al. Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials , 2012, The Lancet.
[29] Gianni Tognoni,et al. Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials , 2012, The Lancet.
[30] O. Dekkers,et al. Use of Aspirin postdiagnosis improves survival for colon cancer patients , 2012, British Journal of Cancer.
[31] S. Gallus,et al. Aspirin and urologic cancer risk: an update , 2012, Nature Reviews Urology.
[32] Rodney J Scott,et al. Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial , 2011, The Lancet.
[33] R. Ali,et al. The utility of Aspirin in dukes C and high risk dukes B colorectal cancer - The ASCOLT study: study protocol for a randomized controlled trial , 2011, Trials.
[34] A. Fulton,et al. Prostaglandin E2 EP receptors as therapeutic targets in breast cancer , 2011, Cancer and Metastasis Reviews.
[35] Richard O Hynes,et al. Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. , 2011, Cancer cell.
[36] Karol Sikora,et al. Delivering affordable cancer care in high-income countries. , 2011, The Lancet. Oncology.
[37] S. Burdett,et al. Aspirin and cancer: has aspirin been overlooked as an adjuvant therapy? , 2011, British Journal of Cancer.
[38] R. Dikshit,et al. Single-injection depot progesterone before surgery and survival in women with operable breast cancer: a randomized controlled trial. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[39] G. Colditz,et al. COX-2 expression predicts worse breast cancer prognosis and does not modify the association with aspirin , 2011, Breast Cancer Research and Treatment.
[40] P. Rothwell,et al. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials , 2011, The Lancet.
[41] A. Ruíz,et al. Adjuvant docetaxel for high-risk, node-negative breast cancer. , 2010, The New England journal of medicine.
[42] C. Mathers,et al. Chronic Diseases: Chronic Diseases and Development 5 Monitoring and surveillance of chronic non-communicable diseases: progress and capacity in high-burden countries , 2010 .
[43] A. Algra,et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials , 2010, The Lancet.
[44] Mats Lambe,et al. Absolute and relative risk of cardiovascular disease in men with prostate cancer: results from the Population-Based PCBaSe Sweden. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[45] Donna Spiegelman,et al. Aspirin intake and survival after breast cancer. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[46] A. Algra,et al. Long-term eff ect of aspirin on colorectal cancer incidence and mortality : 20-year follow-up of fi ve randomised trials , 2010 .
[47] S. Ogino,et al. Aspirin Use and Survival After Diagnosis of Colorectal Cancer , 2009 .
[48] W. Allum,et al. Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[49] T. Hickish,et al. Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[50] R. Collins,et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials , 2009, The Lancet.
[51] I. Ellis,et al. Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trial , 2009, The Lancet.
[52] M. Thun,et al. Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement. , 2009, The Lancet. Oncology.
[53] P. Drew,et al. A Preliminary Study on the Postoperative Survival of Patients Given Aspirin After Resection for Squamous Cell Carcinoma of the Esophagus or Adenocarcinoma of the Cardia , 2009, Annals of Surgical Oncology.
[54] J. Baron,et al. Aspirin for the chemoprevention of colorectal adenomas: meta-analysis of the randomized trials. , 2009, Journal of the National Cancer Institute.
[55] Marc Cohen. Expanding the recognition and assessment of bleeding events associated with antiplatelet therapy in primary care. , 2009, Mayo Clinic proceedings.
[56] D. Bishop,et al. Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. , 2008, The New England journal of medicine.
[57] Deepak L. Bhatt,et al. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. , 2008, Circulation.
[58] M. Lai,et al. Mechanisms underlying aspirin-mediated growth inhibition and apoptosis induction of cyclooxygenase-2 negative colon cancer cell line SW480. , 2008, World journal of gastroenterology.
[59] R. Gelber,et al. Adjuvant chemotherapy with sequential or concurrent anthracycline and docetaxel: Breast International Group 02-98 randomized trial. , 2008, Journal of the National Cancer Institute.
[60] D. Kerr,et al. Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study , 2007, The Lancet.
[61] G. Davı̀,et al. Platelet activation and atherothrombosis. , 2007, The New England journal of medicine.
[62] Taghreed Adam,et al. The burden and costs of chronic diseases in low-income and middle-income countries , 2007, The Lancet.
[63] Yong J. Lee,et al. Aspirin Enhances Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Mediated Apoptosis in Hormone-Refractory Prostate Cancer Cells through Survivin Down-Regulation , 2007, Molecular Pharmacology.
[64] J. Ajani,et al. Long-term results of RTOG trial 8911 (USA Intergroup 113): a random assignment trial comparison of chemotherapy followed by surgery compared with surgery alone for esophageal cancer. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[65] M. Parmar,et al. Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: first results from the MRC RT01 randomised controlled trial. , 2007, The Lancet. Oncology.
[66] Sally Hunsberger,et al. Proposal for standardized definitions for efficacy end points in adjuvant breast cancer trials: the STEEP system. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[67] O. Sansom,et al. Aspirin activates the NF-κB signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer , 2006 .
[68] M. Redlak,et al. Aspirin-Induced Apoptosis in Human Gastric Cancer Epithelial Cells: Relationship with Protein Kinase C Signaling , 2007, Digestive Diseases and Sciences.
[69] C. Mathers,et al. Projections of Global Mortality and Burden of Disease from 2002 to 2030 , 2006, PLoS medicine.
[70] G. Borthwick,et al. Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox‐ independent mechanism , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[71] L. Laine,et al. Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trials. , 2006, The American journal of medicine.
[72] C. V. D. van de Velde,et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. , 2006, The New England journal of medicine.
[73] S. Gutnikov,et al. Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study) , 2005, The Lancet.
[74] P. Drew,et al. Aspirin induces apoptosis in oesophageal cancer cells by inhibiting the pathway of NF‐kappaB downstream regulation of cyclooxygenase‐2 , 2005, ANZ journal of surgery.
[75] M. Piérart,et al. Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911) , 2005, The Lancet.
[76] J. Manson,et al. Low-Dose Aspirin in the Primary Prevention of Cancer: The Women’s Health Study: A Randomized Controlled Trial , 2005, JAMA.
[77] K. Honn,et al. Platelets and cancer metastasis: A causal relationship? , 1992, Cancer and Metastasis Reviews.
[78] J. Massagué,et al. Platelets and metastasis revisited: a novel fatty link. , 2004, The Journal of clinical investigation.
[79] M. Anderson,et al. Review article: management of oesophageal adenocarcinoma — control of acid, bile and inflammation in intervention strategies for Barrett's oesophagus , 2004, Alimentary pharmacology & therapeutics.
[80] R. Botting,et al. Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition , 2004, Pharmacological Reviews.
[81] D. Sliva,et al. Aspirin inhibits highly invasive prostate cancer cells. , 2003, International journal of oncology.
[82] D. Alberts,et al. Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[83] G. Beck,et al. A randomized trial of aspirin to prevent colorectal adenomas. , 2003, The New England journal of medicine.
[84] F. Sinicrope,et al. Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells. , 2002, Cancer research.
[85] D. Dunson,et al. Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis. , 2002, Cancer research.
[86] S. Yusuf,et al. Aspirin-Resistant Thromboxane Biosynthesis and the Risk of Myocardial Infarction, Stroke, or Cardiovascular Death in Patients at High Risk for Cardiovascular Events , 2002, Circulation.
[87] Aller,et al. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. , 2002, The New England journal of medicine.
[88] P. Shekelle,et al. The Vulnerable Elders Survey: A Tool for Identifying Vulnerable Older People in the Community , 2001, Journal of the American Geriatrics Society.
[89] Scott A. Hundahl,et al. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. , 2001, The New England journal of medicine.
[90] B. Levin,et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. , 2000, The New England journal of medicine.
[91] J. Manson,et al. Aspirin Use and Colorectal Cancer: Post-Trial Follow-up Data from the Physicians' Health Study , 1998, Annals of Internal Medicine.
[92] A. D'Amico,et al. Calculated prostate carcinoma volume , 1998, Cancer.
[93] J. Morrow,et al. Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. , 1998, Cancer research.
[94] D. Alberts,et al. Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels. , 1997, Cancer research.
[95] S. Ghosh,et al. Inhibition of NF-kappa B by sodium salicylate and aspirin. , 1994, Science.
[96] N. Cook,et al. Estimating the effect of the run-in on the power of the Physicians' Health Study. , 1991, Statistics in medicine.
[97] J. M. Lang,et al. The use of a run-in to enhance compliance. , 1990, Statistics in medicine.
[98] L F Watson,et al. Colorectal cancer risk, chronic illnesses, operations and medications: case control results from the Melbourne Colorectal Cancer Study. 1988. , 2007, International journal of epidemiology.
[99] C. Mackenzie,et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. , 1987, Journal of chronic diseases.
[100] S. Holm. A Simple Sequentially Rejective Multiple Test Procedure , 1979 .
[101] T. Gasic,et al. Anti-metastatic effect of aspirin. , 1972, Lancet.
[102] Contemporary Clinical Trials , 2022 .