In vivo measurements of thermal load during ablation in high-speed laser corneal refractive surgery.

PURPOSE To evaluate the thermal load of ablation in high-speed laser corneal refractive surgery with the AMARIS excimer laser (SCHWIND eye-tech-solutions). METHODS Thermal load from refractive corrections on human corneas using a 500-Hz laser system with a fluence of 500 mJ/cm(2) and aspheric ablation profiles was recorded with an infrared thermography camera. Each single in vivo measurement was analyzed and temperature values were evaluated. RESULTS Overall, the maximum temperature change of the ocular surface induced by the refractive ablations was ≤4°C. The increase in the peak temperature of the ocular surface never exceeded 35°C in any case. This low thermal load was independent of the amount of correction the eye achieved. CONCLUSIONS The thermal load of the ablation in high-speed laser corneal refractive surgery was minimized using a computer algorithm to control the peak temperature to avoid corneal collagen denaturation with minimal compromise on treatment duration.

[1]  J. Wollensak,et al.  Side effects in excimer corneal surgery , 2005, Graefe's Archive for Clinical and Experimental Ophthalmology.

[2]  M. Netto,et al.  Wavefront-guided ablation: evidence for efficacy compared to traditional ablation. , 2006, American journal of ophthalmology.

[3]  L. O. Svaasand,et al.  Lasers in medicine , 2008 .

[4]  Ulrich Brunsmann,et al.  Evaluation of thermal load during laser corneal refractive surgery using infrared thermography , 2010 .

[5]  I. Aslanides,et al.  LASIK for myopia and astigmatism using the SCHWIND AMARIS excimer laser: an international multicenter trial. , 2010, Journal of refractive surgery.

[6]  M. Arif,et al.  Spot size and quality of scanning laser correction of higher order wavefront aberrations. , 2001, Journal of refractive surgery.

[7]  Holger Baatz,et al.  Comparison of standard and aberration-neutral profiles for myopic LASIK with the SCHWIND ESIRIS platform. , 2009, Journal of refractive surgery.

[8]  A J Welch,et al.  Analysis of thermal relaxation during laser irradiation of tissue , 2001, Lasers in surgery and medicine.

[9]  Christian Hartmann,et al.  Continuous Measurement of Corneal Dehydration With Online Optical Coherence Pachymetry , 2006, Cornea.

[10]  Michael Mrochen,et al.  Simulation of eye-tracker latency, spot size, and ablation pulse depth on the correction of higher order wavefront aberrations with scanning spot laser systems. , 2005, Journal of refractive surgery.

[11]  Optical and Thermal Response of Tissue to Laser Radiation , 2001 .

[12]  M. Mrochen,et al.  Influence of spatial and temporal spot distribution on the ocular surface quality and maximum ablation depth after photoablation with a 1050 Hz excimer laser system , 2009, Journal of cataract and refractive surgery.

[13]  Michael Mrochen,et al.  Effect of time sequences in scanning algorithms on the surface temperature during corneal laser surgery with high‐repetition‐rate excimer laser , 2009, Journal of cataract and refractive surgery.

[14]  Ulrich Brunsmann,et al.  Minimisation of the thermal load of the ablation in high-speed laser corneal refractive surgery: the ‘intelligent thermal effect control’ of the AMARIS platform , 2010 .

[15]  David R Williams,et al.  Effect of beam size on the expected benefit of customized laser refractive surgery. , 2003, Journal of refractive surgery.

[16]  Farhad Hafezi,et al.  Clinical photoablation with a 500-Hz scanning spot excimer laser. , 2004, Journal of refractive surgery.

[17]  D. Pham,et al.  Continuous monitoring of corneal thickness changes during LASIK with online optical coherence pachymetry , 2004, Journal of cataract and refractive surgery.

[18]  R. Srinivasan,et al.  Dynamics of the ultraviolet laser ablation of corneal tissue. , 1987, American journal of ophthalmology.

[19]  W S Kim,et al.  Corneal Hydration Affects Ablation During Laser In Situ Keratomileusis Surgery , 2001, Cornea.

[20]  P B Morgan,et al.  Corneal Temperature Changes During Photorefractive Keratectomy , 1997, Cornea.

[21]  Samuel Arba-Mosquera,et al.  Simulation of the impact of refractive surgery ablative laser pulses with a flying-spot laser beam on intrasurgery corneal temperature. , 2011, Investigative ophthalmology & visual science.

[22]  P B Morgan,et al.  Thermal Consequences of Photorefractive Keratectomy , 2001, Cornea.

[23]  S. Amoils Using a Nidek excimer laser with a rotary epithelial brush and corneal chilling: clinical results. , 1999, Journal of cataract and refractive surgery.