Rapid construction of a whole-genome mutant library by combining haploid stem cells and inducible self-inactivating PiggyBac transposon

[1]  H. Le Hir,et al.  ALFA: annotation landscape for aligned reads , 2019, BMC Genomics.

[2]  Liu Wang,et al.  Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening. , 2017, Cell reports.

[3]  Fidel Ramírez,et al.  deepTools2: a next generation web server for deep-sequencing data analysis , 2016, Nucleic Acids Res..

[4]  Ligong Chen,et al.  The physiological role of drug transporters , 2015, Protein & Cell.

[5]  Korbinian Schneeberger,et al.  Using next-generation sequencing to isolate mutant genes from forward genetic screens , 2014, Nature Reviews Genetics.

[6]  S. Dietmann,et al.  Genetic Exploration of the Exit from Self-Renewal Using Haploid Embryonic Stem Cells , 2014, Cell stem cell.

[7]  E. Lander,et al.  Genetic Screens in Human Cells Using the CRISPR-Cas9 System , 2013, Science.

[8]  Xiu-Jie Wang,et al.  Androgenetic haploid embryonic stem cells produce live transgenic mice , 2012, Nature.

[9]  Austin G Smith,et al.  Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation , 2011, Nature Cell Biology.

[10]  Helga Thorvaldsdóttir,et al.  Integrative Genomics Viewer , 2011, Nature Biotechnology.

[11]  M. DePristo,et al.  The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. , 2010, Genome research.

[12]  D. Adams,et al.  Slingshot: a PiggyBac based transposon system for tamoxifen-inducible ‘self-inactivating’ insertional mutagenesis , 2010, Nucleic acids research.

[13]  Richard Durbin,et al.  Fast and accurate long-read alignment with Burrows–Wheeler transform , 2010, Bioinform..

[14]  Steven J. M. Jones,et al.  Circos: an information aesthetic for comparative genomics. , 2009, Genome research.

[15]  A. Bradley,et al.  A piggyBac transposon-based genome-wide library of insertionally mutated Blm-deficient murine ES cells. , 2009, Genome research.

[16]  B. Doble,et al.  The ground state of embryonic stem cell self-renewal , 2008, Nature.

[17]  Claudia Seisenberger,et al.  Splinkerette PCR for more efficient characterization of gene trap events , 2007, Nature Genetics.

[18]  Min Han,et al.  Efficient Transposition of the piggyBac (PB) Transposon in Mammalian Cells and Mice , 2005, Cell.

[19]  D. Largaespada,et al.  Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system , 2005, Nature.

[20]  T. Magnuson,et al.  Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells , 2000, Nature Genetics.

[21]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[22]  Aaron R. Quinlan,et al.  Bioinformatics Applications Note Genome Analysis Bedtools: a Flexible Suite of Utilities for Comparing Genomic Features , 2022 .