Sites of Anesthetic Inhibitory Action on a Cationic Ligand-Gated Ion Channel.
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[1] Charles H. Bennett,et al. Efficient estimation of free energy differences from Monte Carlo data , 1976 .
[2] J. Barker,et al. Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neurons. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[3] T. Hales,et al. The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones , 1991, British journal of pharmacology.
[4] J. Dilger,et al. Effects of isoflurane on acetylcholine receptor channels. 1. Single-channel currents. , 1992, Molecular pharmacology.
[5] N. Harrison,et al. Positive modulation of human gamma-aminobutyric acid type A and glycine receptors by the inhalation anesthetic isoflurane. , 1993, Molecular pharmacology.
[6] T. Darden,et al. Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems , 1993 .
[7] W. R. Lieb,et al. Molecular and cellular mechanisms of general anaesthesia , 1994, Nature.
[8] B. Brooks,et al. Constant pressure molecular dynamics simulation: The Langevin piston method , 1995 .
[9] D. Raines,et al. General Anesthetics Modify the Kinetics of Nicotinic Acetylcholine Receptor Desensitization at Clinically Relevant Concentrations , 1995, Anesthesiology.
[10] P. Flood,et al. Alpha4beta2 Neuronal Nicotinic Acetylcholine Receptors in the Central Nervous System Are Inhibited by Isoflurane and Propofol, but alpha7‐type Nicotinic Acetylcholine Receptors Are Unaffected , 1997, Anesthesiology.
[11] G. Murshudov,et al. Refinement of macromolecular structures by the maximum-likelihood method. , 1997, Acta crystallographica. Section D, Biological crystallography.
[12] R. Harris,et al. Sites of alcohol and volatile anaesthetic action on GABAA and glycine receptors , 1997, Nature.
[13] L. Lally. The CCP 4 Suite — Computer programs for protein crystallography , 1998 .
[14] Alexander D. MacKerell,et al. All-atom empirical potential for molecular modeling and dynamics studies of proteins. , 1998, The journal of physical chemistry. B.
[15] R. Kubo. Statistical Physics II: Nonequilibrium Statistical Mechanics , 2003 .
[16] R. Eckenhoff,et al. Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane. , 2003, Biochemistry.
[17] Kevin Cowtan,et al. research papers Acta Crystallographica Section D Biological , 2005 .
[18] G. Bricogne,et al. Refinement of severely incomplete structures with maximum likelihood in BUSTER-TNT. , 2004, Acta crystallographica. Section D, Biological crystallography.
[19] Laxmikant V. Kalé,et al. Scalable molecular dynamics with NAMD , 2005, J. Comput. Chem..
[20] Wolfgang Kabsch,et al. Integration, scaling, space‐group assignment and post refinement , 2006 .
[21] J. Changeux,et al. A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family , 2007, Nature.
[22] Jack Snoeyink,et al. Nucleic Acids Research Advance Access published April 22, 2007 MolProbity: all-atom contacts and structure validation for proteins and nucleic acids , 2007 .
[23] Randy J. Read,et al. Phaser crystallographic software , 2007, Journal of applied crystallography.
[24] D. C. Chiara,et al. Identification of Binding Sites in the Nicotinic Acetylcholine Receptor for TDBzl-etomidate, a Photoreactive Positive Allosteric Effector* , 2008, Journal of Biological Chemistry.
[25] R. Dutzler,et al. X-ray structure of a prokaryotic pentameric ligand-gated ion channel , 2008, Nature.
[26] J. Changeux,et al. X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation , 2009, Nature.
[27] R. Dutzler,et al. Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel , 2009, Nature.
[28] R. Dutzler,et al. Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel , 2010, Nature Structural &Molecular Biology.
[29] David N. LeBard,et al. Multiple binding sites for the general anesthetic isoflurane identified in the nicotinic acetylcholine receptor transmembrane domain , 2010, Proceedings of the National Academy of Sciences.
[30] Vincent B. Chen,et al. Correspondence e-mail: , 2000 .
[31] M. H. Cheng,et al. Anesthetic binding in a pentameric ligand-gated ion channel: GLIC. , 2010, Biophysical journal.
[32] P. Corringer,et al. Anesthetic Sensitivity of the Gloeobacter violaceus Proton-Gated Ion Channel , 2010, Anesthesia and analgesia.
[33] D. Mowrey,et al. Isoflurane alters the structure and dynamics of GLIC. , 2011, Biophysical journal.
[34] G. Young,et al. Agonist activation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site , 2008, Proceedings of the National Academy of Sciences.
[35] Randy J. Read,et al. Overview of the CCP4 suite and current developments , 2011, Acta crystallographica. Section D, Biological crystallography.
[36] J. Changeux,et al. X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel , 2011, Nature.
[37] David L Mobley,et al. Alchemical free energy methods for drug discovery: progress and challenges. , 2011, Current opinion in structural biology.
[38] K. Miller,et al. Anesthetic sites and allosteric mechanisms of action on Cys-loop ligand-gated ion channels , 2011, Canadian journal of anaesthesia = Journal canadien d'anesthesie.
[39] Philip R. Evans,et al. An introduction to data reduction: space-group determination, scaling and intensity statistics , 2011, Acta crystallographica. Section D, Biological crystallography.
[40] Roland L. Dunbrack,et al. Assignment of protonation states in proteins and ligands: combining pKa prediction with hydrogen bonding network optimization. , 2012, Methods in molecular biology.
[41] J. Changeux,et al. Structure and pharmacology of pentameric receptor channels: from bacteria to brain. , 2012, Structure.
[42] A. Cohen,et al. Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine. , 2012, Structure.
[43] S. Chakrapani,et al. Desensitization Mechanism in Prokaryotic Ligand-gated Ion Channel , 2012, The Journal of Biological Chemistry.
[44] M. Delarue,et al. A locally closed conformation of a bacterial pentameric proton-gated ion channel , 2012, Nature Structural &Molecular Biology.
[45] P. Zwart,et al. Towards automated crystallographic structure refinement with phenix.refine , 2012, Acta crystallographica. Section D, Biological crystallography.
[46] Jeffery B. Klauda,et al. Improving the CHARMM force field for polyunsaturated fatty acid chains. , 2012, The journal of physical chemistry. B.
[47] Jérôme Hénin,et al. General Anesthetics Predicted to Block the GLIC Pore with Micromolar Affinity , 2012, PLoS Comput. Biol..
[48] J. Changeux,et al. Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation , 2013, Proceedings of the National Academy of Sciences.
[49] M. H. Cheng,et al. Asymmetric ligand binding facilitates conformational transitions in pentameric ligand-gated ion channels. , 2013, Journal of the American Chemical Society.
[50] K. Satyshur,et al. Propofol Binding to the Resting State of the Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Induces Structural Changes in the Inter- and Intrasubunit Transmembrane Domain (TMD) Cavities* , 2013, The Journal of Biological Chemistry.
[51] P. Koehl,et al. Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels , 2013, The EMBO journal.
[52] D. Bertrand,et al. Multisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia chrysanthemi Ligand-gated Ion Channel (ELIC)* , 2013, The Journal of Biological Chemistry.
[53] Edward H. Smith,et al. A propofol binding site on mammalian GABAA receptors identified by photolabeling , 2013, Nature chemical biology.
[54] E. Lindahl,et al. Inhibition versus potentiation of ligand-gated ion channels can be altered by a single mutation that moves ligands between intra- and intersubunit sites. , 2013, Structure.
[55] R. Eckenhoff,et al. Identification of Propofol Binding Sites in a Nicotinic Acetylcholine Receptor with a Photoreactive Propofol Analog* , 2013, The Journal of Biological Chemistry.
[56] M. Delarue,et al. Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel , 2013, Nature Communications.
[57] S. Chakrapani,et al. Structural Basis for Allosteric Coupling at the Membrane-Protein Interface in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC)* , 2013, The Journal of Biological Chemistry.
[58] Peter M. Kasson,et al. GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit , 2013, Bioinform..
[59] Wilfred F van Gunsteren,et al. Practical Aspects of Free-Energy Calculations: A Review. , 2014, Journal of chemical theory and computation.
[60] A. R. Aricescu,et al. Crystal structure of a human GABAA receptor , 2014, Nature.
[61] R. Eckenhoff,et al. Photoaffinity labeling the propofol binding site in GLIC. , 2014, Biochemistry.
[62] R. Eckenhoff,et al. Photoreactive Propofol Analog R ) Identified Using aA ( GABA-Aminobutyric Acid Type A Receptor γ Multiple Propofol-binding Sites in a Neurobiology : , 2014 .
[63] Samuel Genheden,et al. A Large-Scale Test of Free-Energy Simulation Estimates of Protein-Ligand Binding Affinities , 2014, J. Chem. Inf. Model..
[64] E. Gouaux,et al. Glycine receptor mechanism elucidated by electron cryo-microscopy , 2015, Nature.
[65] D. Bertrand,et al. Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor , 2015, Proceedings of the National Academy of Sciences.
[66] Matthieu Chavent,et al. Epock: rapid analysis of protein pocket dynamics , 2014, Bioinform..
[67] T. Smart,et al. The desensitization gate of inhibitory Cys-loop receptors , 2015, Nature Communications.
[68] N. Franks,et al. Mutational Analysis of the Putative High-Affinity Propofol Binding Site in Human β3 Homomeric GABAA Receptors , 2015, Molecular Pharmacology.
[69] N. Franks. Structural Comparisons of Ligand-gated Ion Channels in Open, Closed, and Desensitized States Identify a Novel Propofol-binding Site on Mammalian &ggr;-Aminobutyric Acid Type A Receptors , 2015, Anesthesiology.
[70] N. Colloc'h,et al. Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel , 2016, PloS one.