Perspectives of transurethral robotic laser resection of the prostate: vaporization and coagulation effects with the Nd:YAG laser

A longer operating time and steeper learning curve in mastering the techniques for transurethral laser resection of the prostate are the main problems faced by surgeons compared to standard transurethral resection of the prostate (TURP). However, these disadvantages can be solved with the introduction of a treatment modality designed and developed based on an integrated system of computer, robotics and laser technology. In vitro experiments were carried out to determine variables affecting the vaporization and coagulation lesions, in order to identify the parameters that could optimize this modality. Human cadaveric prostate and fresh chicken breast tissues were irradiated with different parameters using continuous wave Nd:YAG laser fiber in contact with the tissue. The effects of irrigant flowrate, fiber/tissue angle of inclination, number of passes, direction, speed and power of lase on the volume of tissue vaporized and coagulated, were assessed. A non-contact optical coordinate measuring machine was used to measure the depth and width of the vaporized and coagulated lesion. Results reveal that for each directional vaporization path (forward, clockwise and counter-clockwise), power and speed of lase are the most significant parameters influencing the volume of the vaporized and coagulated lesion. Optimized values of the power and speed of lase at 100 W and 1 - 3 mm/s respectively were obtained from the experiments when the tissues were irradiated in the forward, clockwise and counter-clockwise directions. It was concluded from our study to quantify tissue removal and damage, optimized values of irradiation power and speed could be obtained and implemented in the procedure of transurethral robotic laser resection of the prostate.

[1]  J J de la Rosette,et al.  Lasers in the treatment of benign prostatic obstruction: past, present, and future. , 1996, European urology.

[2]  Y Aso,et al.  Holmium: YAG Laser Resection of the Prostate Versus Visual Laser Ablation of the Prostate and Transurethral Ultrasound‐Guided Laser Induced Prostatectomy: A Retrospective Comparative Study , 1998, International journal of urology : official journal of the Japanese Urological Association.

[3]  J. Kabalin,et al.  Neodymium:YAG laser coagulation prostatectomy: 3 years of experience with 227 patients. , 1996, The Journal of urology.

[4]  H A Guess,et al.  Natural history of prostatism: impact of urinary symptoms on quality of life in 2115 randomly selected community men. , 1994, Urology.

[5]  Christiaan F. P. van Swol,et al.  Optimization of dosimetry and safety using the holmium laser for urology , 1998, Photonics West - Biomedical Optics.

[6]  J. Kabalin,et al.  Application of the holmium:YAG laser for prostatectomy. , 1998, Journal of clinical laser medicine & surgery.

[7]  J. Kabalin,et al.  Holmium:yttrium-aluminum-garnet laser prostatectomy. , 1998, Mayo Clinic proceedings.

[8]  David E. Neal,et al.  The morbidity of transurethral resection of the prostate , 1996 .

[9]  K. Matsuoka,et al.  Holmium Laser Resection of the Prostate:HoLRP , 1998 .

[10]  D McLerran,et al.  Further study of the increased mortality following transurethral prostatectomy: a chart-based analysis. , 1990, The Journal of urology.

[11]  H. Whitfield,et al.  Alternative Instrumental Treatments in BPH , 1999 .

[12]  T. Uchida,et al.  [Clinical analysis in 2266 cases of transurethral resection of the prostate]. , 1993, Nihon Hinyokika Gakkai zasshi. The japanese journal of urology.

[13]  A. Tubaro Side-firing neodymium: YAG laser prostatectomy , 1999 .

[14]  Hui-Guo Zhang,et al.  Holmium laser resection of the prostate: preliminary results of the treatment of benign prostatic hyperplasia , 1998, Other Conferences.

[15]  P. Gilling,et al.  Holmium laser resection of the prostate: preliminary results of a new method for the treatment of benign prostatic hyperplasia. , 1996, Urology.

[16]  J. Kabalin,et al.  Holmium laser resection of the prostate versus neodymium:yttrium-aluminum-garnet visual laser ablation of the prostate: a randomized prospective comparison of two techniques for laser prostatectomy. , 1998, Urology.

[17]  H. Lepor,et al.  The efficacy of transurethral resection of the prostate in men with moderate symptoms of prostatism. , 1990, The Journal of urology.

[18]  B Stein,et al.  A prospective randomized comparison of transurethral resection to visual laser ablation of the prostate for the treatment of benign prostatic hyperplasia. , 1995, Urology.

[19]  P. Gilling,et al.  The results of holmium laser resection of the prostate. , 1998, British journal of urology.

[20]  K Matsuoka,et al.  Holmium laser resection of the prostate. , 1998, Journal of endourology.

[21]  Michael Oswald,et al.  Dual-wavelength tissue ablation concept for laser prostatectomy with the Nd:YAG/KTP laser , 1996, European Conference on Biomedical Optics.

[22]  A T Cockett,et al.  Transurethral prostatectomy: immediate and postoperative complications. A cooperative study of 13 participating institutions evaluating 3,885 patients. , 1989, The Journal of urology.

[23]  H. Woo,et al.  Transurethral Needle Ablation (TUNATM) , 1999, European Urology.

[24]  R. Verdaasdonk,et al.  Electrovaporization as a treatment modality for transurethral resection of the prostate: influence of generator type. , 1999, Urology.

[25]  T. Ryan,et al.  Quantitative assessment of variables that influence soft-tissue electrovaporization in a fluid environment. , 1997, Urology.

[26]  T. Wollin,et al.  The holmium laser in urology. , 1998, Journal of clinical laser medicine & surgery.