The insulin-like growth factor I receptor protects tumor cells from apoptosis in vivo.
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J. Kajstura | R. Baserga | D. Abraham | H. Rotman | P. Zoltick | M. Resnicoff | R. Rubin | W. Yutanawiboonchai
[1] D. Coppola,et al. Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumorigenic and induce regression of wild-type tumors. , 1994, Cancer research.
[2] C. Osborne,et al. Growth inhibition of human breast cancer cells in vitro with an antibody against the type I somatomedin receptor. , 1989, Cancer research.
[3] R. Baserga,et al. Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis. , 1995, Cancer research.
[4] A. Ullrich,et al. Constitutive expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor abrogates all requirements for exogenous growth factors. , 1992, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[5] W. Kaelin,et al. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[6] A. Doupe,et al. Expression of a specific marker of avian programmed cell death in both apoptosis and necrosis. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[7] E. Ruoslahti,et al. Association of insulin receptor substrate-1 with integrins. , 1994, Science.
[8] Z. Darżynkiewicz,et al. The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. , 1993, Cancer research.
[9] L. Wang,et al. Distinctive effects of the carboxyl-terminal sequence of the insulin-like growth factor I receptor on its signaling functions , 1993, Journal of virology.
[10] J. Baker,et al. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) , 1993, Cell.
[11] R. Baserga. Oncogenes and the strategy of growth factors , 1994, Cell.
[12] S. Asa,et al. Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[13] G. Evan,et al. c‐Myc‐induced apoptosis in fibroblasts is inhibited by specific cytokines. , 1994, The EMBO journal.
[14] D. Fisher. Apoptosis in cancer therapy: Crossing the threshold , 1994, Cell.
[15] John Calvin Reed,et al. Anchorage dependence, integrins, and apoptosis , 1994, Cell.
[16] W. Rutter,et al. Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation , 1990, Molecular and cellular biology.
[17] P. Porcu,et al. The role of the insulin-like growth factor I receptor in the transformation by simian virus 40 T antigen. , 1994, Oncogene.
[18] M. Tykocinski,et al. Treatment and prevention of rat glioblastoma by immunogenic C6 cells expressing antisense insulin-like growth factor I RNA. , 1993, Science.
[19] C. Rogler,et al. Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice. , 1994, The Journal of biological chemistry.
[20] W. Lee,et al. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis , 1994, Molecular and cellular biology.
[21] J. Swantek,et al. An E2F binding sequence negatively regulates the response of the insulin-like growth factor 1 (IGF-I) promoter to simian virus 40T antigen and to serum. , 1994, Oncogene.
[22] C Collins,et al. Insulin‐like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. , 1986, The EMBO journal.
[23] F. Bresciani,et al. Cell kinetics and growth of squamous cell carcinomas in man. , 1974, Cancer research.
[24] Renato Baserga,et al. The biology of cell reproduction , 1985 .
[25] D. Coppola,et al. Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts , 1994, Molecular and cellular biology.
[26] D. Cheresh,et al. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[27] H. Namiki,et al. Apoptotic cell death induced by serum and its prevention by thiols , 1994, Journal of cellular physiology.
[28] D. Coppola,et al. A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor , 1994, Molecular and cellular biology.
[29] C. Kahn,et al. The insulin signaling system. , 1994, The Journal of biological chemistry.
[30] Elizabeth J. Robertson,et al. Role of insulin-like growth factors in embryonic and postnatal growth , 1993, Cell.
[31] M. Tykocinski,et al. Loss of tumorigenicity of rat glioblastoma directed by episome-based antisense cDNA transcription of insulin-like growth factor I. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[32] D. Coppola,et al. Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor. , 1994, Cancer research.
[33] P. Scott,et al. IL-4- and IL-5-dependent protective immunity to Onchocerca volvulus infective larvae in BALB/cBYJ mice. , 1994, Journal of immunology.
[34] R. Baserga,et al. The insulin-like growth factor I receptor: a key to tumor growth? , 1995, Cancer research.
[35] S. Rockwell,et al. Development of an in vitro assay for the survival of cells suspended from BA1112 rat sarcomas. , 1983, European journal of cancer & clinical oncology.
[36] S. Bayley,et al. Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block. , 1994, Oncogene.
[37] J. Barrett,et al. Regulation of apoptosis by low serum in cells of different stages of neoplastic progression: enhanced susceptibility after loss of a senescence gene and decreased susceptibility after loss of a tumor suppressor gene. , 1994, Cancer research.
[38] L. Helman,et al. In vivo treatment with antibody against IGF-1 receptor suppresses growth of human rhabdomyosarcoma and down-regulates p34cdc2. , 1994, Cancer research.
[39] M. Rubini,et al. The role of the IGF‐I receptor in the growth and transformation of mammalian cells , 1994, Cell proliferation.
[40] M. Rubini,et al. Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[41] A. Ferber,et al. Mitogenicity and transforming activity of the insulin-like growth factor-I receptor with mutations in the tyrosine kinase domain. , 1994, The Journal of biological chemistry.
[42] R. Lanza,et al. Xenogenic humoral responses to islets transplanted in biohybrid diffusion chambers. , 1994, Transplantation.