Balance Control and Peripheral Muscle Function in Aging: A Comparison Between Individuals with Acromegaly and Healthy Subjects.

Advances in the knowledge of acromegaly are leading to an increase in the survival rate of acromegalic subjects. This study was conducted to evaluate balance control, risk of falls, and peripheral muscle function in acromegalic older adults. Seventeen older subjects with acromegaly (67 [63-73] years) and 20 paired control subjects were evaluated with balance scales, force platform, and knee isokinetic dynamometry tests. There were significant differences between the groups on several balance and gait scales, with a worse performance and greater risk of falls in the acromegalic older adults. Acromegalic older adults had lower values for peak torque, maximum repetition of the total work, and total work during extension at 240°/s. The acromegalic older adults had higher values in the medial-lateral range. Acromegaly subjects had lateral instability that compromises their body balance and increases the risk of falls. Moreover, there was a propensity for muscle fatigue in these individuals.

[1]  H. Berry,et al.  The Relationship Between Subjective Falls-Risk Assessment Tools and Functional, Health-Related, and Body Composition Characteristics , 2017, Journal of applied gerontology : the official journal of the Southern Gerontological Society.

[2]  M. Sperling.  Traditional and novel aspects of the metabolic actions of growth hormone. , 2016, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[3]  Seong-Gil Kim,et al.  The intra- and inter-rater reliabilities of the Short Form Berg Balance Scale in institutionalized elderly people , 2015, Journal of physical therapy science.

[4]  F. Sgrò,et al.  ASSESSMENT OF BALANCE ABILITIES IN ELDERLY PEOPLE BY MEANS OF A CLINICAL TEST AND A LOW-COST FORCE PLATE , 2015 .

[5]  A. Lopes,et al.  Scleroderma: Assessment of posture, balance and pulmonary function in a cross-sectional controlled study. , 2015, Clinical biomechanics.

[6]  A. S. Ferreira,et al.  Association among body composition, muscle performance and functional autonomy in older adults , 2015 .

[7]  H. Yavuzer,et al.  Acromegaly and aging: a comparative cross-sectional study. , 2015, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

[8]  A. Lopes,et al.  Posture and balance control in patients with acromegaly: results of a cross-sectional study. , 2014, Gait & posture.

[9]  C. Carmo,et al.  Physical Performance, Balance, Mobility, and Muscle Strength Decline at Different Rates in Elderly People , 2014, Journal of physical therapy science.

[10]  A. Lopes,et al.  On the Functional Capacity and Quality of Life of Patients with Acromegaly: Are They Candidates for Rehabilitation Programs? , 2013, Journal of physical therapy science.

[11]  B. Mazuquin,et al.  Translation, cross-cultural adaptation and analysis of the psychometric properties of the lower extremity functional scale (LEFS): LEFS- BRAZIL. , 2013, Brazilian journal of physical therapy.

[12]  C. Tanaka,et al.  Balance Disturbances in Asthmatic Patients , 2013, The Journal of asthma : official journal of the Association for the Care of Asthma.

[13]  Soo-Kyung Bok,et al.  The Effects of Changes of Ankle Strength and Range of Motion According to Aging on Balance , 2013, Annals of rehabilitation medicine.

[14]  André W O Gil,et al.  Relationship between force platform and two functional tests for measuring balance in the elderly. , 2011, Revista brasileira de fisioterapia (Sao Carlos (Sao Paulo, Brazil)).

[15]  D. S. Pereira,et al.  Muscle strength, muscle balance, physical function and plasma interleukin-6 (IL-6) levels in elderly women with knee osteoarthritis (OA). , 2011, Archives of gerontology and geriatrics.

[16]  J. M. D. Dias,et al.  Cross-cultural adaptation and evaluation of the psychometric properties of the Falls Efficacy Scale-International Among Elderly Brazilians (FES-I-BRAZIL). , 2010, Revista brasileira de fisioterapia (Sao Carlos (Sao Paulo, Brazil)).

[17]  J. Baeyens,et al.  Sarcopenia: European consensus on definition and diagnosis , 2010, Age and ageing.

[18]  Jyrki Kettunen,et al.  Isokinetic quadriceps and hamstring muscle strength and knee function 5 years after anterior cruciate ligament reconstruction: comparison between bone-patellar tendon-bone and hamstring tendon autografts , 2008, Knee Surgery, Sports Traumatology, Arthroscopy.

[19]  Richard W. Bohannon,et al.  Reference values for adult grip strength measured with a Jamar dynamometer: a descriptive meta-analysis , 2006 .

[20]  I. Melzer,et al.  Postural stability in the elderly: a comparison between fallers and non-fallers. , 2004, Age and ageing.

[21]  N. Benjuya,et al.  Aging-induced shifts from a reliance on sensory input to muscle cocontraction during balanced standing. , 2004, The journals of gerontology. Series A, Biological sciences and medical sciences.

[22]  M. Woollacott,et al.  Predicting the probability for falls in community-dwelling older adults using the Timed Up & Go Test. , 2000, Physical therapy.

[23]  T.E. Prieto,et al.  Measures of postural steadiness: differences between healthy young and elderly adults , 1996, IEEE Transactions on Biomedical Engineering.

[24]  Z. Dvir.  Isokinetics : muscle testing, interpretation, and clinical applications , 1995 .

[25]  T. Hortobágyi,et al.  The influence of aging on muscle strength and muscle fiber characteristics with special reference to eccentric strength. , 1995, The journals of gerontology. Series A, Biological sciences and medical sciences.

[26]  P. Kannus,et al.  Isokinetic Evaluation of Muscular Performance , 1994, International journal of sports medicine.

[27]  N. Alexander,et al.  Postural Control in Older Adults , 1994, Journal of the American Geriatrics Society.

[28]  A. Hoffman,et al.  Rheumatologic and skeletal changes in acromegaly. , 1992, Endocrinology and metabolism clinics of North America.

[29]  Diane Podsiadlo,et al.  The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons , 1991, Journal of the American Geriatrics Society.

[30]  M. Tinetti.  Performance‐Oriented Assessment of Mobility Problems in Elderly Patients , 1986, Journal of the American Geriatrics Society.

[31]  M. Davies,et al.  Muscle changes in acromegaly. , 1976, British medical journal.

[32]  T. Harbo,et al.  Maximal isokinetic and isometric muscle strength of major muscle groups related to age, body mass, height, and sex in 178 healthy subjects , 2011, European Journal of Applied Physiology.

[33]  L. Fried,et al.  Epidemiology of aging. , 2000, Epidemiologic reviews.

[34]  E. Bassey,et al.  Longitudinal changes in selected physical capabilities: muscle strength, flexibility and body size. , 1998, Age and ageing.

[35]  A. Schultz,et al.  Muscle strength and rising from a chair in older adults , 1997, Muscle & nerve. Supplement.