Meconium periorchitis presenting as scrotal nodules in a five year old boy.

Meconium peritonitis is a chemical reaction of the peritoneum that occurs when sterile meconium enters the abdominal cavity. This results from an intrauterine perforation of the intestines, which may take place as early as 16 weeks of fetal life. 1 The bowel may self-seal or continue to leak meconium. There is a wide gamut of clinical findings ranging from Jack of symptoms to complete bowel obstruction, requiring urgent surgical intervention shortly after delivery. Dystrophic calcifications commonly are associated with meconium peritonitis and can appear wherever meconium has come into contact with the peritoneum, including the scrotum. These calcifications are pathognomonic for meconium peritonitis and meconium periorchitis and should not be mistaken for a neoplasm.