Pancreas transplantation: the donor’s side of the story

It is refreshing to see pancreas and islet transplantation receiving the international attention it urgently deserves in Dean and colleagues’ State of the Art Review.1 Improving knowledge and understanding of the potential benefits of pancreas transplantation among referring physicians is important, as current referral rates to UK pancreas transplantation centres are low and do not reflect the number of people that could benefit from surgical intervention. Dean’s review focuses on the indications for, and outcomes of, pancreas and islet transplantation.1 But this represents only the recipient’s half of the process and does not acknowledge the major challenges around donors. Pancreas donation comes almost exclusively from dead people, after brain or circulatory death. But two thirds of donor pancreases offered …

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[2]  Douglas E Schaubel,et al.  A Comprehensive Risk Quantification Score for Deceased Donor Kidneys: The Kidney Donor Risk Index , 2009, Transplantation.

[3]  H. Gin,et al.  THE ENDOCRINE PANCREAS IN BRAIN‐DEAD DONORS A PROSPECTIVE STUDY IN 25 PATIENTS , 1993, Transplantation.

[4]  R. Kandaswamy,et al.  The Impact of Donor Obesity on Outcomes after Cadaver Pancreas Transplants , 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[5]  J. Bragg-Gresham,et al.  Characteristics Associated with Liver Graft Failure: The Concept of a Donor Risk Index , 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[6]  A. Matas,et al.  A Composite Risk Model for Predicting Technical Failure in Pancreas Transplantation , 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[7]  M. Baran Pancreas transplantation. , 1982, The Diabetes educator.

[8]  M. Schnitzler,et al.  Patient and Graft Survival Implications of Simultaneous Pancreas Kidney Transplantation From Old Donors , 2007, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[9]  R. Wolfe,et al.  Systematic Evaluation of Pancreas Allograft Quality, Outcomes and Geographic Variation in Utilization , 2010, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.