One-Carbon Metabolism Disorders in Schizophrenia: Genetic and Therapeutic Aspects

[1]  J. Lovegrove,et al.  An update on vitamin B12-related gene polymorphisms and B12 status , 2018, Genes & Nutrition.

[2]  Michael F. Green,et al.  Enhancing Neuroplasticity to Augment Cognitive Remediation in Schizophrenia , 2017, Front. Psychiatry.

[3]  Kevin F. Dowling,et al.  A Cross-Sectional Study of Dietary and Genetic Predictors of Blood Folate Levels in Healthy Young Adults , 2017, Nutrients.

[4]  A. Demjaha On the brink of precision medicine for psychosis: Treating the patient, not the disease A commentary on: Association between serum levels of glutamate and neurotrophic factors and response to clozapine treatment by Krivoy et al. 2017 , 2017, Schizophrenia Research.

[5]  L. DiLalla,et al.  A review of endophenotypes in schizophrenia and autism: The next phase for understanding genetic etiologies , 2017, American journal of medical genetics. Part C, Seminars in medical genetics.

[6]  D. Goff,et al.  Biochemical, physiologic, and clinical effects of L-methylfolate in schizophrenia: A randomized controlled trial , 2017, Molecular Psychiatry.

[7]  A. Gadelha,et al.  Catechol-O-methyltransferase (COMT) polymorphisms modulate working memory in individuals with schizophrenia and healthy controls , 2017, Revista brasileira de psiquiatria.

[8]  G. Snyder,et al.  Dopamine Targeting Drugs for the Treatment of Schizophrenia: Past, 
Present and Future , 2016, Current topics in medicinal chemistry.

[9]  R. Xiao,et al.  Association of MTHFR, SLC19A1 Genetic Polymorphism, Serum Folate, Vitamin B12 and Hcy Status with Cognitive Functions in Chinese Adults , 2016, Nutrients.

[10]  A. Farah,et al.  Correlation of clinical response with homocysteine reduction during therapy with reduced B vitamins in patients with MDD who are positive for MTHFR C677T or A1298C polymorphism: a randomized, double-blind, placebo-controlled study. , 2016, The Journal of clinical psychiatry.

[11]  L. DeLisi,et al.  How precise is precision medicine for schizophrenia? , 2016, Current opinion in psychiatry.

[12]  Pradeep Kumar,et al.  Role of MTHFR C677T gene polymorphism in the susceptibility of schizophrenia: An updated meta-analysis. , 2016, Asian journal of psychiatry.

[13]  J. Roffman,et al.  Emerging Treatments in Schizophrenia: Highlights from Recent Supplementation and Prevention Trials , 2016, Harvard review of psychiatry.

[14]  Dan Wang,et al.  Serum folate levels in schizophrenia: A meta-analysis , 2016, Psychiatry Research.

[15]  M. Cuénod,et al.  Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia , 2016, PloS one.

[16]  A. Blagonravova,et al.  Cognitive Function Dynamics During Folate Augmented Therapy in Patients with Schizophrenia Carrying MTHFR677C>T Gene Polymorphism: a Pilot Study , 2015 .

[17]  I. Imoto,et al.  Evaluation of an association between plasma total homocysteine and schizophrenia by a Mendelian randomization analysis , 2015, BMC Medical Genetics.

[18]  A. MacFarlane,et al.  Genetic modifiers of folate, vitamin B-12, and homocysteine status in a cross-sectional study of the Canadian population. , 2015, The American journal of clinical nutrition.

[19]  A. Malhotra,et al.  Targeting the schizophrenia genome: a fast track strategy from GWAS to clinic , 2015, Molecular Psychiatry.

[20]  K. Morrison,et al.  Novel GCH1 variant in Dopa-responsive dystonia and Parkinson's disease , 2015, Parkinsonism & related disorders.

[21]  M. Haugen,et al.  Effect of genetic polymorphisms involved in folate metabolism on the concentration of serum folate and plasma total homocysteine (p-tHcy) in healthy subjects after short-term folic acid supplementation: a randomized, double blind, crossover study , 2015, Genes & Nutrition.

[22]  C. Demetriou,et al.  Single-nucleotide polymorphisms in one-carbon metabolism genes, Mediterranean diet and breast cancer risk: a case–control study in the Greek-Cypriot female population , 2015, Genes & Nutrition.

[23]  S. Rosset,et al.  Measuring missing heritability: Inferring the contribution of common variants , 2014, Proceedings of the National Academy of Sciences.

[24]  A. Thorsen,et al.  Neurobiology of Cognitive Remediation Therapy for Schizophrenia: A Systematic Review , 2014, Front. Psychiatry.

[25]  I. Silva-Zolezzi,et al.  Geographical and ethnic distribution of single nucleotide polymorphisms within genes of the folate/homocysteine pathway metabolism , 2014, Genes & Nutrition.

[26]  C. Spencer,et al.  Biological Insights From 108 Schizophrenia-Associated Genetic Loci , 2014, Nature.

[27]  C. Kau,et al.  KPG Index versus OPG Measurements: A Comparison between 3D and 2D Methods in Predicting Treatment Duration and Difficulty Level for Patients with Impacted Maxillary Canines , 2014, BioMed research international.

[28]  F. Coppedè,et al.  A Pilot Study Evaluating the Contribution of SLC19A1 (RFC-1) 80G>A Polymorphism to Alzheimer's Disease in Italian Caucasians , 2014, BioMed research international.

[29]  J. Roffman,et al.  Vitamin Supplementation in the Treatment of Schizophrenia , 2014, CNS Drugs.

[30]  R. Shelton,et al.  Effect of adjunctive L-methylfolate 15 mg among inadequate responders to SSRIs in depressed patients who were stratified by biomarker levels and genotype: results from a randomized clinical trial. , 2014, Journal of Clinical Psychiatry.

[31]  K. Ohi,et al.  Meta-analyses of Blood Homocysteine Levels for Gender and Genetic Association Studies of the MTHFR C677T Polymorphism in Schizophrenia , 2014, Schizophrenia bulletin.

[32]  Sumit Sharma,et al.  Serum Folic Acid and RFC A80G Polymorphism in Alzheimer’s Disease and Vascular Dementia , 2014, American journal of Alzheimer's disease and other dementias.

[33]  S. Marder,et al.  Pharmacological approaches to treating negative symptoms: A review of clinical trials , 2013, Schizophrenia Research.

[34]  D. Goff,et al.  Randomized multicenter investigation of folate plus vitamin B12 supplementation in schizophrenia. , 2013, JAMA psychiatry.

[35]  K. Ahmadi,et al.  Unravelling the basis of variability in cobalamin levels in the general population , 2013, British Journal of Nutrition.

[36]  Guifan Sun,et al.  Geographical Distribution of MTHFR C677T, A1298C and MTRR A66G Gene Polymorphisms in China: Findings from 15357 Adults of Han Nationality , 2013, PloS one.

[37]  M. Lenzenweger ENDOPHENOTYPE, INTERMEDIATE PHENOTYPE, BIOMARKER: DEFINITIONS, CONCEPT COMPARISONS, CLARIFICATIONS , 2013, Depression and anxiety.

[38]  D. Goff,et al.  Genetic variation throughout the folate metabolic pathway influences negative symptom severity in schizophrenia. , 2013, Schizophrenia bulletin.

[39]  A. Alachkar,et al.  Association between MTHFR C677T and A1298C, and MTRR A66G polymorphisms and susceptibility to schizophrenia in a Syrian study cohort. , 2012 .

[40]  J. Trent,et al.  Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men. , 2012, Human molecular genetics.

[41]  Mark G. Vangel,et al.  MTHFR 677C>T effects on anterior cingulate structure and function during response monitoring in schizophrenia: a preliminary study , 2011, Brain Imaging and Behavior.

[42]  Piotr Czerski,et al.  MTHFD 1958G>A and MTR 2756A>G polymorphisms are associated with bipolar disorder and schizophrenia , 2007, Psychiatric genetics.

[43]  S. A. Areosa,et al.  Folic acid with or without vitamin B12 for cognition and dementia. , 2003, The Cochrane database of systematic reviews.

[44]  L. Matherly,et al.  Biology of the major facilitative folate transporters SLC19A1 and SLC46A1. , 2014, Current topics in membranes.

[45]  N. Hamajima,et al.  A cross-sectional study to find out the relationship of methylenetetrahydrofolate reductase (MTHFR) C677T genotype with plasma levels of folate and total homocysteine by daily folate intake in Japanese. , 2014, Journal of nutritional science and vitaminology.

[46]  A. Sameer,et al.  Folate: metabolism, genes, polymorphisms and the associated diseases. , 2014, Gene.

[47]  T. McGlashan,et al.  The psychosis high-risk state: a comprehensive state-of-the-art review. , 2013, JAMA psychiatry.

[48]  Wafter B. Van Vort Review in Psychiatry , 1988 .