Crosstalk between histone modifications during the DNA damage response.
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[1] Michael B. Yaffe,et al. RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly , 2007, Cell.
[2] J. Ellenberg,et al. RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins , 2009, Cell.
[3] S. Bekker-Jensen,et al. Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1 , 2005, The Journal of cell biology.
[4] Stephen J. Elledge,et al. MDC1 is a mediator of the mammalian DNA damage checkpoint , 2003, Nature.
[5] Alexander W. Bird,et al. Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair , 2002, Nature.
[6] Rodney Rothstein,et al. Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre , 2003, Nature Cell Biology.
[7] N. Krogan,et al. INO80 and γ-H2AX Interaction Links ATP-Dependent Chromatin Remodeling to DNA Damage Repair , 2004, Cell.
[8] G. Benvenuto,et al. The INO80 protein controls homologous recombination in Arabidopsis thaliana. , 2004, Molecular cell.
[9] S. Elledge,et al. Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage , 2007, Proceedings of the National Academy of Sciences.
[10] John R Yates,et al. Acetylation by Tip60 Is Required for Selective Histone Variant Exchange at DNA Lesions , 2004, Science.
[11] Junjie Chen,et al. Accumulation of Pax2 Transactivation Domain Interaction Protein (PTIP) at Sites of DNA Breaks via RNF8-dependent Pathway Is Required for Cell Survival after DNA Damage* , 2009, Journal of Biological Chemistry.
[12] J. Hoeijmakers. Genome maintenance mechanisms for preventing cancer , 2001, Nature.
[13] Mary B. Kroetz,et al. The Yeast Hex3·Slx8 Heterodimer Is a Ubiquitin Ligase Stimulated by Substrate Sumoylation* , 2007, Journal of Biological Chemistry.
[14] James T Kadonaga,et al. Chromatin remodeling by ATP-dependent molecular machines. , 2003, BioEssays : news and reviews in molecular, cellular and developmental biology.
[15] S. West,et al. ATP-dependent branch migration of holliday junctions promoted by the RuvA and RuvB proteins of E. coli , 1992, Cell.
[16] Andrew J Link,et al. A Protein Complex Containing the Conserved Swi2/Snf2-Related ATPase Swr1p Deposits Histone Variant H2A.Z into Euchromatin , 2004, PLoS biology.
[17] Yang Shi,et al. A YY1–INO80 complex regulates genomic stability through homologous recombination–based repair , 2007, Nature Structural &Molecular Biology.
[18] T. Ried,et al. H2AX Haploinsufficiency Modifies Genomic Stability and Tumor Susceptibility , 2003, Cell.
[19] P. Jeggo,et al. The impact of a negligent G2/M checkpoint on genomic instability and cancer induction , 2007, Nature Reviews Cancer.
[20] S. Jentsch,et al. Chromosome-wide Rad51 spreading and SUMO-H2A.Z-dependent chromosome fixation in response to a persistent DNA double-strand break. , 2009, Molecular cell.
[21] R. Rothstein,et al. Choreography of the DNA Damage Response Spatiotemporal Relationships among Checkpoint and Repair Proteins , 2004, Cell.
[22] Grant W. Brown,et al. Functional Targeting of DNA Damage to a Nuclear Pore-Associated SUMO-Dependent Ubiquitin Ligase , 2008, Science.
[23] Huiming Ding,et al. A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. , 2003, Molecular cell.
[24] M. Tilby,et al. γH2AX Foci Form Preferentially in Euchromatin after Ionising-Radiation , 2007, PloS one.
[25] S. Jackson,et al. Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites. , 2004, Molecular cell.
[26] Edward S. Miller,et al. Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin , 2008, The Journal of cell biology.
[27] Michael Lichten,et al. Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break , 2004, Current Biology.
[28] Junjie Chen,et al. MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks , 2008, Proceedings of the National Academy of Sciences.
[29] K. Dubrana,et al. The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast , 2007, Journal of Cell Science.
[30] Wei-Hua Wu,et al. ATP-Driven Exchange of Histone H2AZ Variant Catalyzed by SWR1 Chromatin Remodeling Complex , 2004, Science.
[31] Steven P Gygi,et al. Abraxas and RAP80 Form a BRCA1 Protein Complex Required for the DNA Damage Response , 2007, Science.
[32] S. Jackson,et al. gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes. , 2006, DNA repair.
[33] Barbara Hohn,et al. Recruitment of the INO80 Complex by H2A Phosphorylation Links ATP-Dependent Chromatin Remodeling with DNA Double-Strand Break Repair , 2004, Cell.
[34] Jiri Bartek,et al. RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins , 2007, Cell.
[35] Xin Wang,et al. A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. , 2007, Molecular cell.
[36] T. Kouzarides. Chromatin Modifications and Their Function , 2007, Cell.
[37] J. Bartek,et al. MDC1 is required for the intra-S-phase DNA damage checkpoint , 2003, Nature.
[38] Aedín C Culhane,et al. RAP80 Targets BRCA1 to Specific Ubiquitin Structures at DNA Damage Sites , 2007, Science.
[39] E. Rogakou,et al. DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139* , 1998, The Journal of Biological Chemistry.
[40] P. Jeggo,et al. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. , 2008, Molecular cell.
[41] Gary D Bader,et al. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry , 2002, Nature.
[42] M. Yaffe,et al. MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks , 2008, Cell.
[43] C. Allis,et al. Chromatin remodeling and cancer, Part II: ATP-dependent chromatin remodeling. , 2007, Trends in molecular medicine.
[44] Jiri Bartek,et al. Mdc1 couples DNA double‐strand break recognition by Nbs1 with its H2AX‐dependent chromatin retention , 2004, The EMBO journal.
[45] R. Marmorstein. Protein modules that manipulate histone tails for chromatin regulation , 2001, Nature Reviews Molecular Cell Biology.
[46] E. Rogakou,et al. Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo , 1999, The Journal of cell biology.
[47] S. Gasser,et al. ATR/Mec1: coordinating fork stability and repair. , 2009, Current opinion in cell biology.
[48] Jacques Côté,et al. The highly conserved and multifunctional NuA4 HAT complex. , 2004, Current opinion in genetics & development.
[49] Laurence Pelletier,et al. Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase , 2007, Science.
[50] Tom J. Petty,et al. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks , 2004, Nature.
[51] R. Bonner,et al. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks , 2003, Nature Cell Biology.
[52] P. Russell,et al. ATM Activation and Its Recruitment to Damaged DNA Require Binding to the C Terminus of Nbs1 , 2005, Molecular and Cellular Biology.
[53] K. Cimprich,et al. ATR: an essential regulator of genome integrity , 2008, Nature Reviews Molecular Cell Biology.
[54] S. Gasser,et al. Ino80 Chromatin Remodeling Complex Promotes Recovery of Stalled Replication Forks , 2008, Current Biology.
[55] B. A. Ballif,et al. ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage , 2007, Science.
[56] Edward S. Miller,et al. The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage , 2009, Cell.
[57] Y. Dou,et al. Histone Ubiquitination Associates with BRCA1-Dependent DNA Damage Response , 2008, Molecular and Cellular Biology.
[58] A. Aguilera,et al. DNA Repair in Mammalian Cells , 2009, Cellular and Molecular Life Sciences.
[59] C. Peterson,et al. Cellular machineries for chromosomal DNA repair. , 2004, Genes & development.
[60] Junjie Chen,et al. Ubiquitin-Binding Protein RAP80 Mediates BRCA1-Dependent DNA Damage Response , 2007, Science.
[61] Michel C. Nussenzweig,et al. Genomic Instability in Mice Lacking Histone H2AX , 2002, Science.
[62] Y. Shiloh,et al. Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway , 2006, Nature Cell Biology.
[63] Jung-Ae Kim,et al. Heterochromatin is refractory to γ-H2AX modification in yeast and mammals , 2007, The Journal of cell biology.
[64] Stephen P. Jackson,et al. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage , 2005, Nature.
[65] Carl Wu,et al. Involvement of actin-related proteins in ATP-dependent chromatin remodeling. , 2003, Molecular cell.
[66] Paul Tempst,et al. WSTF regulates the function of H2A.X via a novel tyrosine kinase activity , 2008, Nature.
[67] F. Xia,et al. The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response. , 2007, Cancer research.
[68] M. Osley,et al. Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae , 2005, Nature.
[69] N. Krogan,et al. Mec1/Tel1 Phosphorylation of the INO80 Chromatin Remodeling Complex Influences DNA Damage Checkpoint Responses , 2007, Cell.
[70] Oscar Fernandez-Capetillo,et al. Focusing on Foci: H2AX and the Recruitment of DNA-Damage Response Factors , 2003, Cell cycle.
[71] C. Peterson,et al. Interplay between Ino80 and Swr1 chromatin remodeling enzymes regulates cell cycle checkpoint adaptation in response to DNA damage. , 2006, Genes & development.
[72] F. Alt,et al. MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals. , 2006, Molecular cell.
[73] C. Peterson,et al. The Ino80 chromatin-remodeling enzyme regulates replisome function and stability , 2008, Nature Structural &Molecular Biology.
[74] Georges Mer,et al. Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair , 2006, Cell.
[75] Junjie Chen,et al. Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains* , 2003, Journal of Biological Chemistry.
[76] J. Lieberman,et al. A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery , 2006, Nature.
[77] Haico van Attikum,et al. The histone code at DNA breaks: a guide to repair? , 2005, Nature Reviews Molecular Cell Biology.
[78] S. Jackson,et al. Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage , 2008, EMBO reports.
[79] S. Gasser,et al. Distinct roles for SWR1 and INO80 chromatin remodeling complexes at chromosomal double‐strand breaks , 2007, The EMBO journal.
[80] George Iliakis,et al. γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin , 2008, Nucleic acids research.
[81] H. Kimura,et al. DNA Damage-Dependent Acetylation and Ubiquitination of H2AX Enhances Chromatin Dynamics , 2007, Molecular and Cellular Biology.
[82] S. Jackson,et al. MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes. , 2004, DNA repair.
[83] Ali Hamiche,et al. A chromatin remodelling complex involved in transcription and DNA processing , 2000, Nature.
[84] T. Hughes,et al. Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[85] T. Uchida,et al. The human actin-related protein hArp5: nucleo-cytoplasmic shuttling and involvement in DNA repair. , 2009, Experimental cell research.
[86] N. Mailand,et al. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin , 2008, The Journal of cell biology.