Dysmorphogenesis of kidney cortical peritubular capillaries in angiopoietin-2-deficient mice.

[1]  G. Yancopoulos,et al.  Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation. , 1999, Journal of the American Society of Nephrology : JASN.

[2]  Q. Al-Awqati,et al.  Metanephric mesenchyme contains embryonic renal stem cells. , 2002, American journal of physiology. Renal physiology.

[3]  A. Woolf,et al.  Proliferation and remodeling of the peritubular microcirculation after nephron reduction: association with the progression of renal lesions. , 2001, The American journal of pathology.

[4]  Ji-Hye Kim,et al.  Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway , 2000, Oncogene.

[5]  Thomas N. Sato,et al.  Increased vascularization in mice overexpressing angiopoietin-1. , 1998, Science.

[6]  G. Yancopoulos,et al.  Complementary and coordinated roles of the VEGFs and angiopoietins during normal and pathologic vascular formation. , 2002, Cold Spring Harbor symposia on quantitative biology.

[7]  L. Truong,et al.  A role for uric acid in the progression of renal disease. , 2002, Journal of the American Society of Nephrology : JASN.

[8]  A. Andres,et al.  EphB4 receptor tyrosine kinase transgenic mice develop glomerulopathies reminiscent of aglomerular vascular shunts , 2003, Mechanisms of Development.

[9]  A. Woolf,et al.  Embryonic gut anomalies in a mouse model of retinoic Acid-induced caudal regression syndrome: delayed gut looping, rudimentary cecum, and anorectal anomalies. , 2001, The American journal of pathology.

[10]  J. Gerdes,et al.  Basic fibroblast growth factor is a morphogenic modulator in kidney vessel development. , 1998, Kidney international.

[11]  M Aguet,et al.  VEGF is required for growth and survival in neonatal mice. , 1999, Development.

[12]  Philippe Soriano,et al.  Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. , 1994, Genes & development.

[13]  G. Vrensen,et al.  In Vivo Angiogenic Phenotype of Endothelial Cells and Pericytes Induced by Vascular Endothelial Growth Factor-A , 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[14]  Thomas N. Sato,et al.  Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. , 1997, Science.

[15]  D. Anderson,et al.  Temporally compartmentalized expression of ephrin-B2 during renal glomerular development. , 2001, Journal of the American Society of Nephrology : JASN.

[16]  P. Campochiaro,et al.  Angiopoietin‐2 plays an important role in retinal angiogenesis , 2002, Journal of cellular physiology.

[17]  Stanley J. Wiegand,et al.  Vascular-specific growth factors and blood vessel formation , 2000, Nature.

[18]  R R Markwald,et al.  Embryonic endothelial cells transdifferentiate into mesenchymal cells expressing smooth muscle actins in vivo and in vitro. , 1997, Circulation research.

[19]  A. Woolf,et al.  Hypoxia up-regulates angiopoietin-2, a Tie-2 ligand, in mouse mesangial cells. , 2000, Kidney international.

[20]  D. Kerjaschki,et al.  Isolation and Characterization of Dermal Lymphatic and Blood Endothelial Cells Reveal Stable and Functionally Specialized Cell Lineages , 2001, The Journal of experimental medicine.

[21]  S. Hirakawa,et al.  Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate , 2002, Developmental dynamics : an official publication of the American Association of Anatomists.

[22]  W. Kriz,et al.  [The lymphatic system of the kidney in some mammals. Light and electron microscopic investigations]. , 1970, Zeitschrift fur Anatomie und Entwicklungsgeschichte.

[23]  K. Tomita,et al.  Vascular endothelial growth factor is an essential molecule for mouse kidney development: glomerulogenesis and nephrogenesis. , 1997, The Journal of clinical investigation.

[24]  P. Campochiaro,et al.  Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1. , 2002, Developmental cell.

[25]  A. Woolf,et al.  Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-A and hypoxia-inducible factor-1 alpha. , 2003, The American journal of pathology.

[26]  J. Grantham.  The kidney: from normal development to congenital disease , 2003 .

[27]  W. Stallcup,et al.  NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[28]  C. Little,et al.  Developmental Biology of the Vascular Smooth Muscle Cell: Building a Multilayered Vessel Wall , 1999, Journal of Vascular Research.

[29]  Pamela F. Jones,et al.  Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis , 1996, Cell.

[30]  C. Betsholtz,et al.  Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli. , 1998, Development.

[31]  S. Harper,et al.  Human podocytes express angiopoietin 1, a potential regulator of glomerular vascular endothelial growth factor. , 2002, Journal of the American Society of Nephrology : JASN.

[32]  G. Garcı́a-Cardeña,et al.  Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors. , 1999, Laboratory investigation; a journal of technical methods and pathology.

[33]  L. Truong,et al.  Role of the microvascular endothelium in progressive renal disease. , 2002, Journal of the American Society of Nephrology : JASN.

[34]  B. Ballermann,et al.  Endothelial cell apoptosis during glomerular capillary lumen formation in vivo. , 2003, Journal of the American Society of Nephrology : JASN.

[35]  K. Alitalo,et al.  A molecular and genetic analysis of renal glomerular capillary development , 1997 .

[36]  K. Alitalo,et al.  A molecular and genetic analysis of renalglomerular capillary development , 2004, Angiogenesis.

[37]  T. Suda,et al.  Increased renal angiopoietin-1 expression in folic acid-induced nephrotoxicity in mice. , 2001, Journal of the American Society of Nephrology : JASN.

[38]  K. Alitalo,et al.  Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2. , 2001, Cardiovascular research.

[39]  C. Betsholtz,et al.  Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. , 1999, Development.

[40]  Czeslaw Radziejewski,et al.  Moving across membranes , 2003, Nature Structural Biology.

[41]  A. Woolf,et al.  Effects of oxygen on vascular patterning in Tie1/LacZ metanephric kidneys in vitro. , 1998, Biochemical and biophysical research communications.

[42]  M. Mrksich,et al.  Direct Cell Adhesion to the Angiopoietins Mediated by Integrins* , 2001, The Journal of Biological Chemistry.

[43]  D. Abrahamson,et al.  Embryonic origin and lineage of juxtaglomerular cells. , 2001, American journal of physiology. Renal physiology.

[44]  W. Kriz,et al.  Das Lymphgefäßsystem der Niere bei einigen Säugetieren. Licht- und elektronenmikroskopische Untersuchungen , 2004, Zeitschrift für Anatomie und Entwicklungsgeschichte.

[45]  R. Boot-Handford,et al.  Receptor Tyrosine Kinase Axl Modulates the Osteogenic Differentiation of Pericytes , 2003, Circulation research.

[46]  R. A. Gomez,et al.  Renin-expressing cells are associated with branching of the developing kidney vasculature. , 1998, Journal of the American Society of Nephrology : JASN.

[47]  Urban Deutsch,et al.  Angiopoietin-1 induces sprouting angiogenesis in vitro , 1998, Current Biology.

[48]  S. Nielsen,et al.  Developmental expression of aquaporin 1 in the rat renal vasculature. , 1999, American journal of physiology. Renal physiology.

[49]  J. Schittny,et al.  Glomerular and Renal Vascular Structural Changes in 8 Integrin-Deficient Mice , 2003 .

[50]  T. Suda,et al.  Expression and potential role of angiopoietins and Tie‐2 in early development of the mouse metanephros , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[51]  D. N. Landon,et al.  Angiopoietin-2 is a site-specific factor in differentiation of mouse renal vasculature. , 2000, Journal of the American Society of Nephrology : JASN.

[52]  J. S. Fong,et al.  Kidney glomeruli. , 1974, Methods in enzymology.

[53]  K. Hirschi,et al.  Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact. , 1999, Circulation research.

[54]  A. Woolf,et al.  The development of kidney blood vessels , 2003 .

[55]  P. S. St. John,et al.  Evidence that embryonic kidney cells expressing flk-1 are intrinsic, vasculogenic angioblasts. , 1996, The American journal of physiology.

[56]  H. Kanetake,et al.  Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn. , 2002, Journal of cell science.