Mid-Term Results Comparing the Use of Artificial Chords Versus Native Chords for Mitral Valve Repair in Children

Background: Our study is aimed at evaluating the mid-term surgical outcomes of mitral valve repair in children using various chordal reconstructive procedures (autologous in situ chords or artificial chords). Methods: A retrospective analysis of 154 patients who underwent mitral valve repair using various chordal reconstructive procedures from 1992 to 2012. Patients were divided into group A and group B based on use of artificial chords and autologous in situ chords, respectively, for the repair. There were 102 (66.2%) patients in group A and 52 (33.8%) patients in group B. The mean age at repair was 11.1 ± 4.5 years. Associated cardiac anomalies were found in 94 (61%) patients. Results: The median follow-up period was 4.2 years (Interquartile range: 2.0-9.9). There were two (1.3%) early deaths and five (3.2%) late deaths. There was no significant difference in survival at 15 years between the two groups (group A: 91.8% vs group B: 95.1%; P = .66). There was no significant difference in the freedom from reoperation at 15 years between group A (79.4%) and group B (97.2%; P = .06). However, there was significant difference in freedom from valve failure between group A (56.5%) and group B (74.1%; P = .03). Carpentier functional class III and postoperative residual mitral regurgitation (2+ MR, ie, mild–moderate MR) were the risk factors for valve failure. Conclusions: Severity of the disease and its progression has profound effect on the valve repair than the technique itself. Both chordal reconstructive procedures can be used to produce satisfactory results in children.

[1]  Sivakumar Sivalingam,et al.  Contemporary long-term outcomes of an aggressive approach to mitral valve repair in children: is it effective and durable for both congenital and acquired mitral valve lesions? , 2014, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[2]  T. Nakano,et al.  A 17-year experience with mitral valve repair with artificial chordae in infants and children. , 2013, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[3]  S. Armstrong,et al.  Chordal replacement with polytetrafluoroethylene sutures for mitral valve repair: a 25-year experience. , 2013, The Journal of thoracic and cardiovascular surgery.

[4]  I. Shiraishi,et al.  Long-term results of mitral valve repair for severe mitral regurgitation in infants: fate of artificial chordae. , 2012, The Annals of thoracic surgery.

[5]  Soo-jin Kim,et al.  Long-term results after mitral valve repair in children. , 2009, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[6]  M. Hazekamp,et al.  Artificial chordae for pediatric mitral and tricuspid valve repair. , 2007, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[7]  L. Nolke,et al.  Mitral valve reconstruction in a pediatric population: late clinical results and predictors of long-term outcome. , 2005, The Journal of thoracic and cardiovascular surgery.

[8]  H. Kado,et al.  Midterm results of mitral valve repair with artificial chordae in children. , 2005, The Journal of thoracic and cardiovascular surgery.

[9]  D. Atkins,et al.  Long-Term Survival After Mitral Valve Replacement in Children Aged <5 Years: A Multi-Institutional Study , 2001, Circulation.

[10]  D. Atkins,et al.  Long-Term Survival After Mitral Valve Replacement in Children Aged <5 Years , 2001 .

[11]  M. Masuda,et al.  Clinical results of mitral valve repair by reconstructing artificial chordae tendineae in children. , 1999, The Journal of thoracic and cardiovascular surgery.

[12]  S. Armstrong,et al.  Replacement of chordae tendineae with Gore-Tex sutures: a ten-year experience. , 1996, The Journal of heart valve disease.

[13]  K S Kunzelman,et al.  The effect of anterior chordal replacement on mitral valve function and stresses. A finite element study. , 1995, ASAIO journal.

[14]  T. David,et al.  Mitral valve repair by replacement of chordae tendineae with polytetrafluoroethylene sutures. , 1991, The Journal of thoracic and cardiovascular surgery.

[15]  A. Carpentier,et al.  Cardiac valve surgery--the "French correction". , 1983, The Journal of thoracic and cardiovascular surgery.

[16]  A Piwnica,et al.  Reconstructive surgery of mitral valve incompetence: ten-year appraisal. , 1980, The Journal of thoracic and cardiovascular surgery.

[17]  F. Ellis,et al.  The experimental and clinical use of autogenous pericardium for the replacement and extension of mitral and tricuspid value cusps and chordae. , 1965, The Journal of cardiovascular surgery.

[18]  A. Carpentier,et al.  Mitral valve repair in children using Carpentier's techniques. , 1999, Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery Annual.

[19]  A. Berrebi,et al.  Reconstructive surgery in congenital mitral valve insufficiency (Carpentier's techniques): long-term results. , 1998, The Journal of thoracic and cardiovascular surgery.