Bithionol inhibits ovarian cancer cell growth In Vitro - studies on mechanism(s) of action
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[1] K. O'Byrne,et al. Targeting Nuclear Factor-Kappa B to Overcome Resistance to Chemotherapy , 2013, Front. Oncol..
[2] Stanley He,et al. MYCN and the epigenome , 2013, Front. Oncol..
[3] Azadeh Meshkini,et al. Involvement of oxidative stress in taxol-induced apoptosis in chronic myelogenous leukemia K562 cells. , 2012, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
[4] E. Bourdon,et al. Autotaxin protects microglial cells against oxidative stress. , 2012, Free radical biology & medicine.
[5] A. Simon,et al. Autophagy in the pathogenesis of myelodysplastic syndrome and acute myeloid leukemia , 2011, Cell cycle.
[6] A. Jemal,et al. Cancer Statistics, 2010 , 2010, CA: a cancer journal for clinicians.
[7] D. Braddock. Autotaxin and lipid signaling pathways as anticancer targets. , 2010, Current opinion in investigational drugs.
[8] R. Agarwal,et al. Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells. , 2010, Cellular signalling.
[9] Ruili Huang,et al. Identification of known drugs that act as inhibitors of NF-kappaB signaling and their mechanism of action. , 2010, Biochemical pharmacology.
[10] D. Braddock,et al. Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion , 2008, Molecular Cancer Therapeutics.
[11] Y. Yoshida,et al. DNA-binding activity of NF-kappaB and phosphorylation of p65 are induced by N-acetylcysteine through phosphatidylinositol (PI) 3-kinase. , 2008, Molecular immunology.
[12] S. Kaye,et al. The Bcl-2/Bcl-XL Family Inhibitor ABT-737 Sensitizes Ovarian Cancer Cells to Carboplatin , 2007, Clinical Cancer Research.
[13] Yan Xu,et al. Lysophosphatidic acid downregulates tissue inhibitor of metalloproteinases, which are negatively involved in lysophosphatidic acid-induced cell invasion , 2007, Oncogene.
[14] R. Carón,et al. Mifepristone Inhibits Ovarian Cancer Cell Growth In vitro and In vivo , 2007, Clinical Cancer Research.
[15] R. Gust,et al. Non Platinum Metal Complexes as Anti‐cancer Drugs , 2007, Archiv der Pharmazie.
[16] T. Herzog. The current treatment of recurrent ovarian cancer , 2006, Current oncology reports.
[17] D. Green,et al. Staining of suspension cells with hoechst 33258 to detect apoptosis. , 2006, CSH protocols.
[18] Dong-Hyun Kim,et al. Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line. , 2005, Gynecologic oncology.
[19] K. Conklin. Chemotherapy-Associated Oxidative Stress: Impact on Chemotherapeutic Effectiveness , 2004, Integrative cancer therapies.
[20] W. Gregory,et al. Long‐term survival in 463 women treated with platinum analogs for advanced epithelial carcinoma of the ovary: life expectancy compared to women of an age‐matched normal population , 2004, International journal of gynecological cancer : official journal of the International Gynecological Cancer Society.
[21] A. Parrill,et al. Molecular mechanisms of lysophosphatidic acid action. , 2003, Progress in lipid research.
[22] E. Venkatraman,et al. Platinum retreatment of platinum-resistant ovarian cancer after nonplatinum therapy. , 2003, Gynecologic oncology.
[23] R. Agarwal,et al. Ovarian cancer: strategies for overcoming resistance to chemotherapy , 2003, Nature Reviews Cancer.
[24] P. Elson,et al. Unfolding the pathophysiological role of bioactive lysophospholipids. , 2003, Current drug targets. Immune, endocrine and metabolic disorders.
[25] J. Chun,et al. Lysophosphatidic acid as a novel cell survival/apoptotic factor. , 2002, Biochimica et biophysica acta.
[26] Yusuke Nakamura,et al. Involvement of FKHR-Dependent TRADD Expression in Chemotherapeutic Drug-Induced Apoptosis , 2002, Molecular and Cellular Biology.
[27] B. Aggarwal,et al. Chemopreventive Agents Induce Suppression of Nuclear Factor‐κB Leading to Chemosensitization , 2002, Annals of the New York Academy of Sciences.
[28] W. V. Berghe,et al. Regulation of the transcriptional activity of the nuclear factor-κB p65 subunit , 2002 .
[29] E. Shacter,et al. Distinct Modes of Cell Death Induced by Different Reactive Oxygen Species , 2002, The Journal of Biological Chemistry.
[30] Michael Fraser,et al. Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway. , 2002, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[31] Y. S. Kim,et al. Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor. , 2001, Cancer research.
[32] Y. Kikuchi. [The mechanism of cisplatin-resistance in ovarian cancer]. , 2001, Human cell.
[33] G. Mills,et al. XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells. , 2001, Cancer research.
[34] G. Gores,et al. Apoptosis in cancer: cause and cure , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.
[35] K. Irani. Oxidant signaling in vascular cell growth, death, and survival : a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling. , 2000, Circulation research.
[36] M. Piccart,et al. Randomized intergroup trial of cisplatin-paclitaxel versus cisplatin-cyclophosphamide in women with advanced epithelial ovarian cancer: three-year results. , 2000, Journal of the National Cancer Institute.
[37] W. El-Deiry,et al. Cell cycle control as a basis for cancer drug development (Review). , 2000, International journal of oncology.
[38] W. Earnshaw,et al. Induction of apoptosis by cancer chemotherapy. , 2000, Experimental cell research.
[39] J. Buolamwini. Cell cycle molecular targets in novel anticancer drug discovery. , 2000, Current pharmaceutical design.
[40] Suk Woo Nam,et al. Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells , 2000, Oncogene.
[41] J. Cusack,et al. NF- kappa B and chemoresistance: potentiation of cancer drugs via inhibition of NF- kappa B. , 1999, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[42] James M. Roberts,et al. CDK inhibitors: positive and negative regulators of G1-phase progression. , 1999, Genes & development.
[43] R. Kinscherf,et al. Modulating apoptosis: current applications and prospects for future drug development. , 1999, Current medicinal chemistry.
[44] J. Cusack,et al. Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB , 1999, Nature Medicine.
[45] R. Weinberg,et al. Cell-cycle control and its watchman , 1996, Nature.
[46] J. Warwick,et al. The prognostic significance of Bcl-2 and p53 expression in ovarian carcinoma. , 1996, Cancer research.
[47] E. Partridge,et al. Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer , 1996, The New England journal of medicine.
[48] J C Reed,et al. The control of apoptosis and drug resistance in ovarian cancer: influence of p53 and Bcl-2. , 1995, Oncogene.
[49] G. Mills,et al. Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.
[50] G. Kroemer,et al. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death , 1995, The Journal of experimental medicine.
[51] James M. Roberts,et al. Inhibitors of mammalian G1 cyclin-dependent kinases. , 1995, Genes & development.
[52] S. Elledge,et al. Inhibition of cyclin-dependent kinases by p21. , 1995, Molecular biology of the cell.
[53] C. Sherr. G1 phase progression: Cycling on cue , 1994, Cell.
[54] Y. Bacq,et al. Successful treatment of acute fascioliasis with bithionol , 1991, Hepatology.
[55] W. Leonard,et al. Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[56] H. G. Khorana,et al. Studies on polynucleotides , 1965 .
[57] W. E. Razzell,et al. Studies on polynucleotides. III. Enzymic degradation; substrate specificity and properties of snake venom phosphodiesterase. , 1959, The Journal of biological chemistry.
[58] Oliver H. Lowry,et al. Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.
[59] S. Linder,et al. Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA , 2007, International journal of cancer.
[60] G. Haegeman,et al. Regulation of the transcriptional activity of the nuclear factor-kappaB p65 subunit. , 2002, Biochemical pharmacology.
[61] Jiayuh Lin,et al. Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis. , 2000, Anticancer research.
[62] H. Arts,et al. Options for modulation of drug resistance in ovarian cancer. , 2000, International journal of gynecological cancer : official journal of the International Gynecological Cancer Society.
[63] M. Sano,et al. Chemotherapy of Paragonimiasis with Bithionol. II. Clinical Observations on the Treatment with Bithionol. , 1961 .