A Clinical Decision Support System for the Treatment of Irradiated Persons Based on Mathematical Model of Granulocytopoiesis
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Abstract In this paper a decision support system to assist the medical doctor in the treatment of irradiated persons is presented. The nucleus of this system is a biomathematical model of granulocytopoiesis. This special cell renewal system contains fundamental biological information and, consequently, serves as one of the most important biomedical indicators to judge the severeness of irradiation cases. Two representative example cases conclude the paper.
[1] John A. Nelder,et al. A Simplex Method for Function Minimization , 1965, Comput. J..
[2] Theodor M. Fliedner,et al. Simulationsmodelle von Perturbationen des granulozytären Zellerneuerungssystems , 1987 .
[3] Theodor M. Fliedner,et al. Modern Control Theory as a Tool to Describe the Biomathematical Model of Granulocytopoiesis , 1990, Analyse dynamischer Systeme in Medizin, Biologie und Ökologie.