Matrix heparan sulphate, but not endothelial cell surface heparan sulphate, is degraded by highly metastatic mouse lymphoma cells.

Background and aims. This survey was conducted to provide statistical data regarding publications in PubMedindexed journals from Tabriz University of Medical Sciences Faculty of Dentistry. Materials and methods. The database used for this study was PubMed. The search was conducted using key words including the names of the heads of the departments. Papers published between January 1, 2005 and April 31, 2012 were considered. The retrieved abstracts were reviewed and unrelated articles were excluded. Data were transferred to Microsoft Excel software for descriptive statistical analyses. Results. A total of 158 papers matched the inclusion criteria, with the majority from the Department of Endodontics (49 articles). The highest proportion (48.3%) of papers was related to in vitro studies, followed by clinical trials, in vivo studies, and case reports. The number of publications showed a considerable increase over the studied period. Conclusion. PubMed-indexed publications from different departments have increased steadily, suggesting that research has become an essential component in the evaluated institute.

[1]  M. Eghbal,et al.  A Scientometric Study of PubMed-Indexed Endodontic Articles: A Comparison between Iran and Other Regional Countries , 2012, Iranian endodontic journal.

[2]  M. Eghbal,et al.  Published Endodontic Articles in PubMed-Indexed Journals from Iran , 2012, Iranian endodontic journal.

[3]  V. Schirrmacher,et al.  Clonal analysis of expression of tumor-associated transplantation antigens and of metastatic capacity , 2004, Cancer Immunology, Immunotherapy.

[4]  D. Schwartz,et al.  Tumor invasion and host extracellular matrix , 2004, Cancer and Metastasis Reviews.

[5]  V. Schirrmacher,et al.  Mechanism of Transendothelial Cell Passage and Matrix Degradation by Metastatic Tumor Cells , 1987 .

[6]  H. Furthmayr,et al.  Isolation and characterization of basement membrane and cell proteoheparan sulphates from HR9 cells. , 1986, European journal of biochemistry.

[7]  M. Poupon,et al.  Solubilization and degradation of extracellular matrix by various metastatic cell lines derived from a rat rhabdomyosarcoma. , 1986, Journal of the National Cancer Institute.

[8]  V. Schirrmacher,et al.  Involvement of both heparanase and plasminogen activator in lymphoma cell‐mediated degradation of heparan sulfate in the subendothelial extracellular matrix , 1986, Journal of cellular physiology.

[9]  M. Lyon,et al.  Structure and function of heparan sulphate proteoglycans. , 1986, The Biochemical journal.

[10]  P. Mühlradt,et al.  Glycoconjugates of murine tumor lines with different metastatic capacities. II. Diversity of glycolipid composition , 1985, International journal of cancer.

[11]  Z. Fuks,et al.  Sequential degradation of heparan sulfate in the subendothelial extracellular matrix by highly metastatic lymphoma cells , 1985, International journal of cancer.

[12]  Z. Fuks,et al.  Characterization of an extracellular matrix-degrading protease derived from a highly metastatic tumor cell line. , 1985, European journal of cancer & clinical oncology.

[13]  V. Schirrmacher,et al.  Glycoconjugates of murine tumor lines with different metastatic capacities. I. Differences in fucose utilization and in glycoprotein patterns , 1984, International journal of cancer.

[14]  R. Kramer,et al.  Selective degradation of basement membrane macromolecules by metastatic melanoma cells. , 1984, Journal of the National Cancer Institute.

[15]  Z. Fuks,et al.  Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: relationship to tumor cell metastasis. , 1983, Cancer research.

[16]  T. Irimura,et al.  Heparan sulfate degradation: relation to tumor invasive and metastatic properties of mouse B16 melanoma sublines. , 1983, Science.

[17]  P. Altevogt,et al.  Metastatic potential severely altered by changes in tumor cell adhesiveness and cell-surface sialylation , 1983, The Journal of experimental medicine.

[18]  Z. Fuks,et al.  Lymphoma cell interaction with cultured vascular endothelial cells and with the subendothelial basal lamina: attachment, invasion and morphological appearance. , 1983, Invasion & metastasis.

[19]  P. Altevogt,et al.  Different expression of Lyt differentiation antigens and cell surface glycoproteins by a murine T lymphoma line and its highly metastatic variant , 1982, European journal of immunology.

[20]  M. Lohmann‐Matthes,et al.  Tumor metastases and cell‐mediated immunity in a model system in DBA/2 mice. I. Tumor invasiveness in vitro and metastasis formation in vivo , 1979, International journal of cancer.

[21]  M. Höök,et al.  Glycosaminoglycans and their binding to biological macromolecules. , 1978, Annual review of biochemistry.