Noninvasive ventilation as a palliative measure

Purpose of reviewDyspnea is a distressing consequence of many unremitting diseases. This review discusses the therapeutic use of noninvasive ventilation (NIV) in advanced illness. Recent findingsNIV continues to be investigated most rigorously in patients with progressive neuromuscular weakness and the combination of emphysema and lung cancer. Data are quite limited on the palliative role of NIV in bronchiectasis and interstitial lung diseases. It remains difficult to identify the subsets of patients with acute-on-chronic respiratory failure who are most likely to benefit from ICU admission, but NIV may particularly help those with hypercapnia. The question of whether general or disease-specific instruments should be used to evaluate the effects of NIV on quality of life is unanswered. Computerized decision aids have been developed to assist providers, patients, and their families with advance care planning. SummaryNIV is an important adjunct to medications for patients with intractable dyspnea. Future research should attempt to clarify the effectiveness of NIV at controlling dyspnea within and outside the hospital. Barriers to its domiciliary application are largely unknown. Processes should be developed to optimize communication among clinicians, patients, and their caregivers around the issues of when to start NIV and how to withdraw it at the end of life.

[1]  J. Masip,et al.  Noninvasive ventilation in acute respiratory failure , 2014, International journal of chronic obstructive pulmonary disease.

[2]  R. Aantaa,et al.  Is the effect of non-invasive ventilation on survival in amyotrophic lateral sclerosis age-dependent? , 2013, BMC Palliative Care.

[3]  S. Jaber,et al.  Non-invasive ventilation for end-of-life oncology patients. , 2013, The Lancet. Oncology.

[4]  S. Nava,et al.  Palliative use of non-invasive ventilation in end-of-life patients with solid tumours: a randomised feasibility trial. , 2013, The Lancet. Oncology.

[5]  J. Bach,et al.  Diaphragm pacing and noninvasive respiratory management of amyotrophic lateral sclerosis/motor neuron disease , 2012, Muscle & nerve.

[6]  S. Gandevia,et al.  An algorithm for the safety of costal diaphragm electromyography derived from ultrasound , 2012, Muscle & nerve.

[7]  A. Moreau,et al.  Clinical assessment for identifying causes of acute respiratory failure in cancer patients , 2012, European Respiratory Journal.

[8]  Jianxing He,et al.  Successful treatment of gefitinib-induced acute interstitial pneumonitis with corticosteroid and non-invasive BIPAP-ventilation. , 2012, Journal of thoracic disease.

[9]  G. Ehninger,et al.  Respiratory failure in patients undergoing allogeneic hematopoietic SCT—a randomized trial on early non-invasive ventilation based on standard care hematology wards , 2012, Bone Marrow Transplantation.

[10]  Michael J. Green,et al.  Accuracy of a Decision Aid for Advance Care Planning: Simulated End-of-Life Decision Making , 2011, The Journal of Clinical Ethics.

[11]  J. Bach,et al.  Duchenne Muscular Dystrophy: Continuous Noninvasive Ventilatory Support Prolongs Survival , 2011, Respiratory Care.

[12]  Michael J. Green,et al.  Advance care planning for patients with ALS: Feasibility of an interactive computer program , 2011, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

[13]  S. Pastores,et al.  Intensive care of the cancer patient: recent achievements and remaining challenges , 2011, Annals of intensive care.

[14]  S. Chevret,et al.  Diagnostic strategy for hematology and oncology patients with acute respiratory failure: randomized controlled trial. , 2010, American journal of respiratory and critical care medicine.

[15]  Arthur S Slutsky,et al.  Early CPAP prevents evolution of acute lung injury in patients with hematologic malignancy , 2010, Intensive Care Medicine.

[16]  C. Schmoor,et al.  High-intensity versus low-intensity non-invasive ventilation in patients with stable hypercapnic COPD: a randomised crossover trial , 2010, Thorax.

[17]  D. Annane,et al.  Mechanical ventilation for amyotrophic lateral sclerosis/motor neuron disease , 2010, The Cochrane database of systematic reviews.

[18]  J. Decruyenaere,et al.  The impact of the initial ventilatory strategy on survival in hematological patients with acute hypoxemic respiratory failure. , 2010, Journal of critical care.

[19]  B. Fauroux.  Noninvasive ventilation in cystic fibrosis , 2010, Expert review of respiratory medicine.

[20]  D. Harrison,et al.  Admission factors associated with hospital mortality in patients with haematological malignancy admitted to UK adult, general critical care units: a secondary analysis of the ICNARC Case Mix Programme Database , 2009, Critical care.

[21]  S. Nava,et al.  Non-invasive ventilation in acute respiratory failure , 2009, The Lancet.

[22]  M. A. Bassani,et al.  Noninvasive ventilation in a pregnant patient with respiratory failure from all-trans-retinoic-acid (ATRA) syndrome. , 2009, Respiratory care.

[23]  R. Mcevoy,et al.  Nocturnal non-invasive nasal ventilation in stable hypercapnic COPD: a randomised controlled trial , 2009, Thorax.

[24]  R. Kacmarek.  Should noninvasive ventilation be used with the do-not-intubate patient? , 2009, Respiratory care.

[25]  W. Windisch.  Impact of home mechanical ventilation on health-related quality of life , 2008, European Respiratory Journal.

[26]  H. Kerstjens,et al.  Nocturnal non-invasive ventilation in addition to rehabilitation in hypercapnic patients with COPD , 2008, Thorax.

[27]  K. Kostikas,et al.  One-year non-invasive ventilation in chronic hypercapnic COPD: effect on quality of life. , 2008, Respiratory medicine.

[28]  E. Bruera,et al.  Comparison of symptom burden among patients referred to palliative care with hematologic malignancies versus those with solid tumors. , 2008, Journal of palliative medicine.

[29]  V. Viallon,et al.  Temporal changes in management and outcome of septic shock in patients with malignancies in the intensive care unit* , 2008, Critical care medicine.

[30]  W. Kinnear,et al.  Effect of non-invasive ventilation on respiratory muscle loading and endurance in patients with Duchenne muscular dystrophy , 2007, Thorax.

[31]  T. Kotsimbos,et al.  Randomised placebo controlled trial of non-invasive ventilation for hypercapnia in cystic fibrosis , 2007, Thorax.

[32]  J. Rabkin,et al.  Palliative care for patients with amyotrophic lateral sclerosis: "prepare for the worst and hope for the best". , 2007, JAMA.

[33]  D. Cook,et al.  Noninvasive positive pressure ventilation in critical and palliative care settings: Understanding the goals of therapy* , 2007, Critical care medicine.

[34]  C. Wiener,et al.  Early use of non‐invasive ventilation prolongs survival in subjects with ALS , 2007, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

[35]  M. Carvalho,et al.  Sleep characteristics of amyotrophic lateral sclerosis in patients with preserved diaphragmatic function , 2007, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.

[36]  A. Soubani,et al.  Outcome and prognostic factors of lung cancer patients admitted to the medical intensive care unit , 2006, European Respiratory Journal.

[37]  D. Hess.  Noninvasive ventilation in neuromuscular disease: equipment and application. , 2006, Respiratory care.

[38]  D. Mahler,et al.  Mechanisms and measurement of dyspnea in chronic obstructive pulmonary disease. , 2006, Proceedings of the American Thoracic Society.

[39]  L. Goldstein,et al.  The effect of noninvasive ventilation on ALS patients and their caregivers , 2006, Neurology.

[40]  J. Mira,et al.  Outcome of critically ill allogeneic hematopoietic stem-cell transplantation recipients: a reappraisal of indications for organ failure supports. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[41]  P. Shaw,et al.  Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial , 2006, The Lancet Neurology.

[42]  P. Andersen,et al.  EFNS task force on management of amyotrophic lateral sclerosis: guidelines for diagnosing and clinical care of patients and relatives , 2005, European journal of neurology.

[43]  A K Simonds,et al.  Randomised controlled trial of non-invasive ventilation (NIV) for nocturnal hypoventilation in neuromuscular and chest wall disease patients with daytime normocapnia , 2005, Thorax.

[44]  R. Kacmarek,et al.  Noninvasive positive pressure ventilation reverses acute respiratory failure in select “do-not-intubate” patients , 2005, Critical care medicine.

[45]  Y. Kondoh,et al.  Health-related quality of life in patients with idiopathic pulmonary fibrosis. What is the main contributing factor? , 2005, Respiratory medicine.

[46]  R. Elashoff,et al.  Correlation of the degree of dyspnea with health-related quality of life, functional abilities, and diffusing capacity for carbon monoxide in patients with systemic sclerosis and active alveolitis: results from the Scleroderma Lung Study. , 2005, Arthritis and rheumatism.

[47]  M. Antonelli,et al.  Noninvasive mechanical ventilation as a palliative treatment of acute respiratory failure in patients with end-stage solid cancer , 2004, Palliative medicine.

[48]  M. Levy,et al.  Outcomes of patients with do-not-intubate orders treated with noninvasive ventilation* , 2004, Critical care medicine.

[49]  J. Decruyenaere,et al.  Outcome in noninvasively and invasively ventilated hematologic patients with acute respiratory failure. , 2004, Chest.

[50]  H. Selvadurai,et al.  Outcome of non-invasive positive pressure ventilation in paediatric neuromuscular disease , 2004, Archives of Disease in Childhood.

[51]  M. Antonelli,et al.  Treatment of acute respiratory failure by helmet-delivered non-invasive pressure support ventilation in children with acute leukemia: a pilot study , 2004, Intensive Care Medicine.

[52]  A. Siderowf,et al.  Nocturnal Oximetry: Utility in the Respiratory Management of Amyotrophic Lateral Sclerosis , 2003, American journal of physical medicine & rehabilitation.

[53]  T. Voit,et al.  Longterm noninvasive ventilation in children and adolescents with neuromuscular disorders , 2003, European Respiratory Journal.

[54]  M. Elliott,et al.  Domiciliary non-invasive ventilation for recurrent acidotic exacerbations of COPD: an economic analysis , 2003, Thorax.

[55]  A. Simonds.  Ethics and decision making in end stage lung disease , 2003, Thorax.

[56]  T. Voit,et al.  Daytime predictors of sleep disordered breathing in children and adolescents with neuromuscular disorders , 2003, Neuromuscular Disorders.

[57]  J. Wedzicha,et al.  Non-invasive positive pressure ventilation to treat respiratory failure resulting from exacerbations of chronic obstructive pulmonary disease: Cochrane systematic review and meta-analysis , 2003, BMJ : British Medical Journal.

[58]  A. Smyth,et al.  Chronic respiratory failure: an unusual cause and treatment , 2002, Thorax.

[59]  S. Bourke,et al.  Sleep and breathing in neuromuscular disease , 2002, European Respiratory Journal.

[60]  G. Rosa,et al.  Noninvasive ventilation in the treatment of acute respiratory failure induced by all-trans retinoic acid (retinoic acid syndrome) in children with acute promyelocytic leukemia , 2002, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[61]  R. Barohn,et al.  A preliminary evaluation of a prospective study of pulmonary function studies and symptoms of hypoventilation in ALS/MND patients , 2001, Journal of the Neurological Sciences.

[62]  L. Goldstein,et al.  The effect of non-invasive positive pressure ventilation (NIPPV) on cognitive function in amyotrophic lateral sclerosis (ALS): a prospective study , 2001, Journal of neurology, neurosurgery, and psychiatry.

[63]  B. Lanini,et al.  Perception of dyspnea in patients with neuromuscular disease. , 2001, Chest.

[64]  S. Chevret,et al.  Improved survival in cancer patients requiring mechanical ventilatory support: Impact of noninvasive mechanical ventilatory support , 2001, Critical care medicine.

[65]  A. Arroliga,et al.  Objective measures of the efficacy of noninvasive positive‐pressure ventilation in amyotrophic lateral sclerosis , 2001, Muscle & nerve.

[66]  N. Pavlidis,et al.  Chemotherapy-Induced Noncardiogenic Pulmonary Edema Related to Gemcitabine plus Docetaxel Combination with Granulocyte Colony-Stimulating Factor Support , 2000, Respiration.

[67]  A. Baydur,et al.  Long term non-invasive ventilation in the community for patients with musculoskeletal disorders: 46 year experience and review , 2000, Thorax.

[68]  W. David,et al.  Polysomnographic studies in amyotrophic lateral sclerosis 1 This manuscript was presented, in part, at the 7th International Symposium on ALS/MND, Chicago, Illinois, November, 1996. 1 , 1997, Journal of the Neurological Sciences.

[69]  D. Gozal.  Nocturnal ventilatory support in patients with cystic fibrosis: comparison with supplemental oxygen. , 1997, The European respiratory journal.

[70]  I. Smith,et al.  Long term non-invasive domiciliary assisted ventilation for respiratory failure following thoracoplasty. , 1994, Thorax.

[71]  P. Calverley,et al.  Respiratory effort perception at rest and during carbon dioxide rebreathing in patients with dystrophia myotonica. , 1994, Thorax.

[72]  V. Dubowitz,et al.  Night-time nasal ventilation in neuromuscular disease , 1990, The Lancet.

[73]  A. Woolnough,et al.  Twenty-four hour noninvasive ventilation in Duchenne muscular dystrophy: a safe alternative to tracheostomy. , 2013, Canadian respiratory journal.

[74]  P. Gay.  Complications of noninvasive ventilation in acute care. , 2009, Respiratory care.

[75]  Keenan,et al.  Complications of Noninvasive Ventilation in Acute Care. Discussion , 2009 .

[76]  T. Berghmans,et al.  Noninvasive ventilation: application to the cancer patient admitted in the intensive care unit , 2002, Supportive Care in Cancer.

[77]  A. Bühlmann.  [Pathophysiology of dyspnea]. , 1989, Schweizerische medizinische Wochenschrift.

[78]  H. Mitsumoto,et al.  Subcommittee of the American Academy of Neurology Evidence-based Review) : Report of the Quality Standards Management, and Cognitive/behavioral Impairment (an Amyotrophic Lateral Sclerosis: Multidisciplinary Care, Symptom Practice Parameter Update: the Care of the Patient With , 2022 .