Genome wide association study identifies novel potential candidate genes for bovine milk cholesterol content
暂无分享,去创建一个
[1] F. Schenkel,et al. Genetic parameters of milk cholesterol content in Holstein cattle , 2018, Canadian Journal of Animal Science.
[2] I. Schulman. Liver X receptors link lipid metabolism and inflammation , 2017, FEBS letters.
[3] P. Strzyz. Cell Senescence: A new role for ATM , 2017, Nature Reviews Molecular Cell Biology.
[4] P. Strzyz. Lipid Metabolism: Cholesterol feeds into cell growth control , 2017, Nature Reviews Molecular Cell Biology.
[5] J. Iqbal,et al. Hexim1 heterozygosity stabilizes atherosclerotic plaque and decreased steatosis in ApoE null mice fed atherogenic diet. , 2017, The international journal of biochemistry & cell biology.
[6] C. Albrecht,et al. In vitro characterization and endocrine regulation of cholesterol and phospholipid transport in the mammary gland , 2017, Molecular and Cellular Endocrinology.
[7] Dianfan Li,et al. Cholesterol homeostasis: How do cells sense sterol excess? , 2016, Chemistry and physics of lipids.
[8] E. Ibeagha-Awemu,et al. High density genome wide genotyping-by-sequencing and association identifies common and low frequency SNPs, and novel candidate genes influencing cow milk traits , 2016, Scientific Reports.
[9] A. Zimmer,et al. Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism , 2016, Biochimica et biophysica acta.
[10] M. Woodward,et al. Total cholesterol as a risk factor for coronary heart disease and stroke in women compared with men: A systematic review and meta-analysis. , 2016, Atherosclerosis.
[11] Amy E. Morgan,et al. Cholesterol metabolism: A review of how ageing disrupts the biological mechanisms responsible for its regulation , 2016, Ageing Research Reviews.
[12] G. Morahan,et al. A common variant association study reveals novel susceptibility loci for low HDL‐cholesterol levels in ethnic Arabs , 2016, Clinical genetics.
[13] P. Dudemaine,et al. Transcriptome adaptation of the bovine mammary gland to diets rich in unsaturated fatty acids shows greater impact of linseed oil over safflower oil on gene expression and metabolic pathways , 2016, BMC Genomics.
[14] Sanghoon Moon,et al. Genome-wide association study of serum lipids confirms previously reported associations as well as new associations of common SNPs within PCSK7 gene with triglyceride , 2016, Journal of Human Genetics.
[15] U. Kulozik,et al. Temporal variation of milk fat globule diameter, fat and cholesterol content and milk epithelial cell gene expression in dairy cows , 2015 .
[16] Y. Jang,et al. The Impact of CDH13 Polymorphism and Statin Administration on TG/HDL Ratio in Cardiovascular Patients , 2015, Yonsei medical journal.
[17] D. Rader,et al. Association of HDL cholesterol efflux capacity with incident coronary heart disease events: a prospective case-control study , 2015, The lancet. Diabetes & endocrinology.
[18] J. Gross,et al. Response of the Cholesterol Metabolism to a Negative Energy Balance in Dairy Cows Depends on the Lactational Stage , 2015, PloS one.
[19] E. Arenas. Faculty Opinions recommendation of Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. , 2015 .
[20] J. Mathers,et al. Effects of the Dietary Approach to Stop Hypertension (DASH) diet on cardiovascular risk factors: a systematic review and meta-analysis. , 2015, The British journal of nutrition.
[21] Davide Heller,et al. STRING v10: protein–protein interaction networks, integrated over the tree of life , 2014, Nucleic Acids Res..
[22] N. Davidson,et al. Epigenetic reprogramming in breast cancer: From new targets to new therapies , 2014, Annals of medicine.
[23] J. Gross,et al. Cholesterol metabolism, transport, and hepatic regulation in dairy cows during transition and early lactation. , 2014, Journal of dairy science.
[24] P. Ridker. LDL cholesterol: controversies and future therapeutic directions , 2014, The Lancet.
[25] F. Schenkel,et al. A new approach for efficient genotype imputation using information from relatives , 2014, BMC Genomics.
[26] Qin Zhang,et al. Genome Wide Association Study Identifies 20 Novel Promising Genes Associated with Milk Fatty Acid Traits in Chinese Holstein , 2014, PloS one.
[27] R Core Team,et al. R: A language and environment for statistical computing. , 2014 .
[28] Kuljeet Singh,et al. The Role of Tight Junctions in Mammary Gland Function , 2014, Journal of Mammary Gland Biology and Neoplasia.
[29] M. Rychlik,et al. Effects of rapeseed and soybean oil dietary supplementation on bovine fat metabolism, fatty acid composition and cholesterol levels in milk , 2013, Journal of Dairy Research.
[30] R. Bruckmaier,et al. Hepatic gene expression involved in glucose and lipid metabolism in transition cows: effects of fat mobilization during early lactation in relation to milk performance and metabolic changes. , 2013, Journal of dairy science.
[31] H. Lu,et al. Enhancer of zeste homolog 2 activates wnt signaling through downregulating CXXC finger protein 4 , 2013, Cell Death and Disease.
[32] C. Albrecht,et al. Characteristics and Functional Relevance of Apolipoprotein-A1 and Cholesterol Binding in Mammary Gland Tissues and Epithelial Cells , 2013, PloS one.
[33] Xueyuan Cao,et al. Polymorphisms of PTPN11 gene could influence serum lipid levels in a sex-specific pattern , 2013, Lipids in Health and Disease.
[34] E. Chen,et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.
[35] R. Summers,et al. Relaxin family peptides and their receptors. , 2013, Physiological reviews.
[36] Xiaolong Wang,et al. Identification and Dissection of Four Major QTL Affecting Milk Fat Content in the German Holstein-Friesian Population , 2012, PloS one.
[37] R. Ringseis,et al. Changes in the expression of hepatic genes involved in cholesterol homeostasis in dairy cows in the transition period and at different stages of lactation. , 2012, Journal of dairy science.
[38] Lisa J. Martin,et al. Accounting for a Quantitative Trait Locus for Plasma Triglyceride Levels: Utilization of Variants in Multiple Genes , 2012, PloS one.
[39] Y. Kokubo,et al. CDH13 gene coding t‐cadherin influences variations in plasma adiponectin levels in the Japanese population , 2012, Human mutation.
[40] H. Ahammer,et al. Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice , 2011, Biochimica et biophysica acta.
[41] G. Ness,et al. Mechanism of Resistance to Dietary Cholesterol , 2011, Journal of lipids.
[42] C. Carlson,et al. Genetic Determinants of Lipid Traits in Diverse Populations from the Population Architecture using Genomics and Epidemiology (PAGE) Study , 2011, PLoS genetics.
[43] M. T. Sorensen,et al. Identification of ABCA1 and ABCG1 in milk fat globules and mammary cells--implications for milk cholesterol secretion. , 2011, Journal of dairy science.
[44] D. Figeys,et al. Lipin - The bridge between hepatic glycerolipid biosynthesis and lipoprotein metabolism. , 2010, Biochimica et biophysica acta.
[45] C. Wijmenga,et al. Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study. , 2010, Atherosclerosis.
[46] P. Ma,et al. Genome Wide Association Studies for Milk Production Traits in Chinese Holstein Population , 2010, PloS one.
[47] Avi Ma'ayan,et al. ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments , 2010, Bioinform..
[48] M. Olivier,et al. Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels. , 2010, Physiological genomics.
[49] J. A. Arias,et al. Epigenetic Regulation of Milk Production in Dairy Cows , 2010, Journal of Mammary Gland Biology and Neoplasia.
[50] Aaron R. Quinlan,et al. BIOINFORMATICS APPLICATIONS NOTE , 2022 .
[51] Jihong Han,et al. Inhibition of ERK1/2 and Activation of Liver X Receptor Synergistically Induce Macrophage ABCA1 Expression and Cholesterol Efflux* , 2009, The Journal of Biological Chemistry.
[52] M. Kaske,et al. Cholesterol synthesis in the lactating cow: Induced expression of candidate genes , 2009, The Journal of Steroid Biochemistry and Molecular Biology.
[53] Hiromu Suzuki,et al. Decreased expression of CXXC4 promotes a malignant phenotype in renal cell carcinoma by activating Wnt signaling , 2009, Oncogene.
[54] Christian Gieger,et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts , 2009, Nature Genetics.
[55] Fan Lan,et al. SIRT1 Regulates Hepatocyte Lipid Metabolism through Activating AMP-activated Protein Kinase* , 2008, Journal of Biological Chemistry.
[56] D. Strachan,et al. LDL-cholesterol concentrations: a genome-wide association study , 2008, The Lancet.
[57] Brad T. Sherman,et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.
[58] H. Snieder,et al. SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women. , 2007, Atherosclerosis.
[59] A. Gotto,et al. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. , 2007, The New England journal of medicine.
[60] Simon C. Potter,et al. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.
[61] Ole F. Christensen,et al. Proceedings, 10 World Congress of Genetics Applied to Livestock Production DMU - A Package for Analyzing Multivariate Mixed Models in quantitative Genetics and Genomics , 2014 .
[62] S. Bray. Notch signalling: a simple pathway becomes complex , 2006, Nature Reviews Molecular Cell Biology.
[63] S. Patton,et al. Origins of the cholesterol in milk , 1980, Lipids.
[64] M. Eilers,et al. Transcriptional regulation and transformation by Myc proteins , 2005, Nature Reviews Molecular Cell Biology.
[65] S. Miura,et al. Increased Very Low Density Lipoprotein Secretion and Gonadal Fat Mass in Mice Overexpressing Liver DGAT1* , 2005, Journal of Biological Chemistry.
[66] Mark Daly,et al. Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..
[67] S. Davis,et al. Decreased expression of β1‐integrin and focal adhesion kinase in epithelial cells may initiate involution of mammary glands , 2004, Journal of cellular physiology.
[68] Michel Georges,et al. Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[69] H. Thomsen,et al. The DGAT1 K232A mutation is not solely responsible for the milk production quantitative trait locus on the bovine chromosome 14. , 2004, Journal of dairy science.
[70] U. Lendahl,et al. Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors. , 2004, Experimental cell research.
[71] R. Fries,et al. Assessment of the gene content of the chromosomal regions flanking bovine DGAT1. , 2004, Genomics.
[72] D. Hardie. Printed in U.S.A. Copyright © 2003 by The Endocrine Society doi: 10.1210/en.2003-0982 Minireview: The AMP-Activated Protein Kinase Cascade: The Key Sensor of Cellular Energy Status , 2022 .
[73] J. Breslow,et al. Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mices⃞s⃞ The online version of this article (available at http://www.jlr.org) contains one supplemental table. Published, JLR Papers in Press, August 1, 2003. DOI 10.1194/jlr.M300203-JLR200 , 2003, Journal of Lipid Research.
[74] Hitoshi Shimano,et al. Cross-talk between peroxisome proliferator-activated receptor (PPAR) alpha and liver X receptor (LXR) in nutritional regulation of fatty acid metabolism. I. PPARs suppress sterol regulatory element binding protein-1c promoter through inhibition of LXR signaling. , 2003, Molecular endocrinology.
[75] Didier Boichard,et al. Detection of genes influencing economic traits in three French dairy cattle breeds , 2003, Genetics Selection Evolution.
[76] M. de Oya,et al. Food sources of nutrients in the diet of Spanish children: the Four Provinces Study , 2003, British Journal of Nutrition.
[77] B. A. Janowski. The hypocholesterolemic agent LY295427 up-regulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBP , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[78] R. Aebersold,et al. Crucial Step in Cholesterol Homeostasis Sterols Promote Binding of SCAP to INSIG-1, a Membrane Protein that Facilitates Retention of SREBPs in ER , 2002, Cell.
[79] S. Gabriel,et al. The Structure of Haplotype Blocks in the Human Genome , 2002, Science.
[80] Yanhong Shi,et al. The peroxisome proliferator-activated receptor δ, an integrator of transcriptional repression and nuclear receptor signaling , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[81] R. G. Jensen. The composition of bovine milk lipids: January 1995 to December 2000. , 2002, Journal of dairy science.
[82] S. Kliewer,et al. A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[83] E. Ikonen,et al. How cells handle cholesterol. , 2000, Science.
[84] Jean-Marc A. Lobaccaro,et al. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ , 2000 .
[85] M. Peaker,et al. Transport of milk constituents by the mammary gland. , 2000, Physiological reviews.
[86] I. Shimomura,et al. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. , 2000, Genes & development.
[87] D. Fletouris,et al. Rapid determination of cholesterol in milk and milk products by direct saponification and capillary gas chromatography. , 1998, Journal of dairy science.
[88] R. Hammer,et al. Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα , 1998, Cell.
[89] J. Hokanson,et al. Plasma Triglyceride Level is a Risk Factor for Cardiovascular Disease Independent of High-Density Lipoprotein Cholesterol Level: A Metaanalysis of Population-Based Prospective Studies , 1996, Journal of cardiovascular risk.
[90] B. Groner,et al. Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[91] E. Nigg,et al. Cyclin‐dependent protein kinases: Key regulators of the eukaryotic cell cycle , 1995, BioEssays : news and reviews in molecular, cellular and developmental biology.
[92] H. Cheng,et al. Zonation of cholesterol and glycerolipid synthesis in regenerating rat livers , 1993, Hepatology.
[93] G. Vassaux,et al. Cholesterol efflux from adipose cells is coupled to diacylglycerol production and protein kinase C activation. , 1990, Biochemical and biophysical research communications.
[94] A. Sim,et al. The AMP-activated protein kinase: a multisubstrate regulator of lipid metabolism , 1989 .
[95] P. Yeagle. Cholesterol and the cell membrane. , 1985, Biochimica et biophysica acta.
[96] P. Leder,et al. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor , 1983, Cell.
[97] R. G. Jensen. Composition of bovine milk lipids , 1973, Journal of the American Oil Chemists' Society.
[98] U. Bracco,et al. Lipid composition of the fat globule membrane of human and bovine milk. , 1972, Journal of dairy science.