Experimental studies on the role of serotonin in cognition

[1]  H. Aihara,et al.  Serotonin-2 receptor-mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of rat , 1988, Neuropharmacology.

[2]  M M Mesulam,et al.  Large‐scale neurocognitive networks and distributed processing for attention, language, and memory , 1990, Annals of neurology.

[3]  M. Raiteri,et al.  Release‐Regulating Serotonin 5‐HT1D Autoreceptors in Human Cerebral Cortex , 1993, Journal of neurochemistry.

[4]  P. Potter,et al.  Effect of cholinergic deficit induced by ethylcholine aziridinium on serotonergic parameters in rat brain , 1987, Neuroscience.

[5]  P. L. Carlton,et al.  Attenuated habituation due to parachlorophenylalanine. , 1973, Pharmacology, biochemistry, and behavior.

[6]  D. McCormick,et al.  Neurotransmitter actions in the thalamus and cerebral cortex. , 1992, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[7]  L. Squire,et al.  The medial temporal lobe memory system , 1991, Science.

[8]  P. Riekkinen,et al.  Interaction between raphe dorsalis and nucleus basalis magnocellularis in spatial learning , 1990, Brain Research.

[9]  P. Jäkälä,et al.  The effects of alaproclate and p-chlorophenylalanine on cued navigation performance in rats , 1992, Journal of neural transmission. Parkinson's disease and dementia section.

[10]  C. Perego,et al.  Age-related changes in metabolic responses to chronic monoamine depletion in central dopaminergic and serotonergic systems of rats treated with reserpine , 1987, Neurobiology of Aging.

[11]  J. Gray,et al.  The psychology of fear and stress , 1971 .

[12]  P. Bonate,et al.  Serotonin receptor subtypes: functional, physiological, and clinical correlates. , 1991, Clinical neuropharmacology.

[13]  M. Gallagher,et al.  Markers for biogenic amines in the aged rat brain: Relationship to decline in spatial learning ability , 1990, Neurobiology of Aging.

[14]  E. Rolls,et al.  The latency of activation of neurones in the lateral hypothalamus and substantia innominata during feeding in the monkey , 1979, Brain Research.

[15]  R. Bartus.  The need for common perspectives in the development and use of animal models for age-related cognitive and neurodegenerative disorders , 1988, Neurobiology of Aging.

[16]  T. Bliss,et al.  Reduction of long‐term potentiation in the dentate gyrus of the rat following selective depletion of monoamines. , 1983, The Journal of physiology.

[17]  J. Sirviö,et al.  Brain and cerebrospinal fluid cholinesterases in Alzheimer's disease, Parkinson's disease and aging. A critical review of clinical and experimental studies , 1992, Journal of neural transmission. Parkinson's disease and dementia section.

[18]  H. Eichenbaum,et al.  The hippocampus--what does it do? , 1992, Behavioral and neural biology.

[19]  D. McCormick,et al.  Serotonin and noradrenaline excite GABAergic neurones of the guinea‐pig and cat nucleus reticularis thalami. , 1991, The Journal of physiology.

[20]  C. Heyes,et al.  Pharmacological mechanisms and animal models of cognition. , 1992, Behavioural pharmacology.

[21]  S. Iversen,et al.  Handbook of Psychopharmacology , 1988, Springer US.

[22]  L. Valzelli,et al.  Effect of p-chlorophenylalanine on avoidance learning of two differentially housed mouse strains. , 1979, Neuropsychobiology.

[23]  P. Jäkälä,et al.  The effects of increased serotonergic and decreased cholinergic activities on spatial navigation performance in rats , 1991, Pharmacology Biochemistry and Behavior.

[24]  L. Záborszky.  Synaptic Organization of Basal Forebrain Cholinergic Projection Neurons , 1992 .

[25]  I. Törk.  Anatomy of the Serotonergic System a , 1990, Annals of the New York Academy of Sciences.

[26]  J. Aggleton,et al.  Both fornix and anterior thalamic, but not mammillary, lesions disrupt delayed non-matching-to-position memory in rats , 1991, Behavioural Brain Research.

[27]  R. Morris.  Developments of a water-maze procedure for studying spatial learning in the rat , 1984, Journal of Neuroscience Methods.

[28]  S. Peroutka.  5‐Hydroxytryptamine Receptors , 1993, Journal of neurochemistry.

[29]  R. North,et al.  5-hydroxytryptamine is a fast excitatory transmitter at 5-HT3 receptors in rat amygdala , 1992, Neuron.

[30]  M. Hadfield,et al.  Regional brain monoamine levels and utilization in middle-aged rats. , 1990, Life sciences.

[31]  M. Segal,et al.  Serotonin attenuates a slow inhibitory postsynaptic potential in rat hippocampal neurons , 1990, Neuroscience.

[32]  C. Köhler,et al.  Open field activity and avoidance behavior following serotonin depletion: A comparison of the effects of parachlorophenylalanine and electrolytic midbrain raphe lesions , 1978, Pharmacology Biochemistry and Behavior.

[33]  E. Azmitia,et al.  Enhanced spatial discrimination learning in rats following 5,7-DHT-induced serotonergic deafferentation of the hippocampus , 1990, Brain Research.

[34]  Howard Eichenbaum,et al.  LTP and memory: can we enhance the connection? , 1993, Trends in Neurosciences.

[35]  P. Jäkälä,et al.  The effects of THA on scopolamine and nucleus basalis lesion-induced EEG slowing , 1991, Brain Research Bulletin.

[36]  C. H. Vanderwolf.  Near-total loss of ‘learning’ and ‘memory’ as a result of combined cholinergic and serotonergic blockade in the rat , 1987, Behavioural Brain Research.

[37]  G. Aghajanian,et al.  Electrophysiology of the Central Serotonin System: Receptor Subtypes and Transducer Mechanisms a , 1990, Annals of the New York Academy of Sciences.

[38]  K. Hole,et al.  5,7-Dihydroxytryptamine lesions of the ascending 5-hydroxytryptamine pathways: Habituation, motor activity and agonistic behavior , 1977, Pharmacology Biochemistry and Behavior.

[39]  F. Monsma,et al.  Biochemical and behavioral evidence for muscarinic autoreceptors in the CNS , 1990, Brain Research.

[40]  H. Steinbusch,et al.  Aberrant morphology of serotonergic fibers in the forebrain of the aged rat , 1988, Neuroscience Letters.

[41]  V. Luine,et al.  Spatial memory deficits in aged rats: contributions of monoaminergic systems , 1990, Brain Research.

[42]  R. Miettinen,et al.  Loss of cholinergic neurons in the nucleus basalis induces neocortical electroencephalographic and passive avoidance deficits , 1992, Neuroscience.

[43]  W. Mcentee,et al.  Age‐associated memory impairment , 1990, Neurology.

[44]  J. Langston,et al.  The amine-depleting effects of 5,7-dihydroxytryptamine (5,7-DHT) in C57BL/6 mice do not increase with age , 1989, Brain Research.

[45]  H. Ladinsky,et al.  Evidence of an interaction between serotoninergic and cholinergic neurons in the corpus striatum and hippocampus of the rat brain , 1978, Brain Research.

[46]  David G. Morgan,et al.  Serotonin-2 binding sites in human frontal cortex and hippocampus. Selective loss of S-2A sites with age , 1984, Brain Research.

[47]  G. Aston-Jones,et al.  Cortically projecting nucleus basalis neurons in rat are physiologically heterogeneous , 1984, Neuroscience Letters.

[48]  G. Vantini,et al.  Changes in monamines and their metabolite levels in some brain regions of aged rats , 1982, Neurobiology of Aging.

[49]  A. Bjo¨rklund,et al.  Acetylcholine release in the hippocampus: regulation by monoaminergic afferents as assessed by in vivo microdialysis , 1992, Brain Research.

[50]  Alfred W. Kaszniak,et al.  Communication and Cognition in Normal Aging and Dementia , 1987 .

[51]  C. H. Vanderwolf.  Behavior-related cortical activity and swim-to-platform performance in the aged rat , 1992, Behavioural Brain Research.

[52]  F. Reinoso-suárez,et al.  Changes in biogenic amines in rat hippocampus during development and aging. , 1988, Life sciences.

[53]  M. Carli,et al.  8-Hydroxy-2-(di-n-propylamino)tetralin, a 5-HT1A receptor agonist, impairs performance in a passive avoidance task. , 1992, European journal of pharmacology.

[54]  M. Carli,et al.  8‐Hydroxy‐2‐(di‐n‐propylamino)tetralin impairs spatial learning in a water maze: role of postsynaptic 5‐HT1A receptors , 1992, British journal of pharmacology.

[55]  J. Changeux.  The TiPS lecture. The nicotinic acetylcholine receptor: an allosteric protein prototype of ligand-gated ion channels. , 1990, Trends in pharmacological sciences.

[56]  J. Sirviö,et al.  Effects of combined methysergide and mecamylamine/scopolamine treatment on spatial navigation , 1992, Brain Research.

[57]  K. Davis,et al.  Implications of multiple transmitter system lesions for cholinomimetic therapy in Alzheimer's disease. , 1990, Progress in brain research.

[58]  G. Wenk,et al.  Serotonin influences the behavioral recovery of rats following nucleus basalis lesions , 1991, Pharmacology Biochemistry and Behavior.

[59]  C. Gottfries.  Clinical and Neurochemical Aspects of Diseases with Cognitive Impairment , 1992, Reviews in the neurosciences.

[60]  G. Pepeu,et al.  Does 5-hydroxytryptamine influence cholinergic mechanisms in the central nervous system? , 1974, Advances in biochemical psychopharmacology.

[61]  W. D. Wise,et al.  Differential behavioral and neurochemical effects following lesions of the dorsal or median raphe nuclei in rats. , 1974, Brain research.

[62]  G. Buzsáki,et al.  Electric activity in the neocortex of freely moving young and aged rats , 1988, Neuroscience.

[63]  B. Jacobs,et al.  Hippocampal mediation of raphe lesion- and PCPA-induced hyperactivity in the rat , 1975, Brain Research.

[64]  M. Segal,et al.  The effects of serotonin depletion and raphe grafts on hippocampal electrophysiology and behavior , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[65]  E. Perry,et al.  Memory following cholinergic (NBM) and noradrenergic (DNAB) lesions made singly or in combination: Potentiation of disruption by scopolamine , 1990, Pharmacology Biochemistry and Behavior.

[66]  K. E. Moore,et al.  Destruction of 5-hydroxytryptaminergic neurons and the dynamics of dopamine in nucleus accumbens septi and other forebrain regions of the rat , 1981, Neuropharmacology.

[67]  R. Morris,et al.  The Cholinergic Hypothesis of Memory: A Review of Animal Experiments , 1988 .

[68]  A. Björklund,et al.  Combined cholinergic and serotonergic denervation of the forebrain produces severe deficits in a spatial learning task in the rat , 1988, Brain Research.

[69]  D. Middlemiss,et al.  Centrally active 5-HT receptor agonists and antagonists , 1992, Neuroscience & Biobehavioral Reviews.

[70]  R. Miettinen,et al.  Interaction between raphe dorsalis and nucleus basalis magnocellularis in the regulation of high-voltage spindle activity in rat neocortex , 1990, Brain Research.

[71]  J. R. Rush,et al.  Spatial working memory in rats: Effects of monoaminergic antagonists , 1983, Pharmacology Biochemistry and Behavior.

[72]  S. Iversen,et al.  Psychopharmacology of the aging nervous system , 1988 .

[73]  H. Soininen,et al.  Neurotransmitter changes in alzheimer's disease: Implications to diagnostics and therapy , 1990, Journal of neuroscience research.

[74]  P. Solomon,et al.  Disruption of latent inhibition following systemic administration of parachlorophenylalanine (PCPA) , 1978, Physiology & Behavior.

[75]  D. Jenden,et al.  Effects of combined serotonin depletion and lesions of the nucleus basalis magnocellularis on acquisition of a complex spatial discrimination task in the rat , 1990, Brain Research.

[76]  P. Fletcher.  A comparison of the effects of dorsal or median raphe injections of 8-OH-DPAT in three operant tasks measuring response inhibition , 1993, Behavioural Brain Research.

[77]  Y. Lamour,et al.  Age-related changes in dopaminergic and serotonergic indices in the rat forebrain , 1989, Neurobiology of Aging.

[78]  J. Fozard,et al.  The 5-HT4 receptor: a place in the sun. , 1992, Trends in pharmacological sciences.

[79]  M. Riva,et al.  Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment. , 1988, Pharmacology & toxicology.

[80]  R. Vertes,et al.  Dorsal raphe neurons: synchronous discharge with the theta rhythm of the hippocampus in the freely behaving rat. , 1992, Journal of neurophysiology.

[81]  L. Butcher,et al.  Neurotransmitter Interactions and Cognitive Function , 1992, Birkhäuser Boston.

[82]  T. Jessell,et al.  5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[83]  M. Raiteri,et al.  5‐Hydroxytryptamine3 Receptors Sited on Cholinergic Axon Terminals of Human Cerebral Cortex Mediate Inhibition of Acetylcholine Release , 1992, Journal of neurochemistry.

[84]  H. Fibiger,et al.  Electrolytic, but not 5,7-dihydroxytryptamine, lesions of the nucleus medianus raphe impair acquisition of a radial maze task. , 1985, Behavioral and neural biology.

[85]  A. Hunter.  Serotonergic involvement in learning and memory. , 1989, Biochemical Society transactions.

[86]  R. Nicoll,et al.  Functional comparison of neurotransmitter receptor subtypes in mammalian central nervous system. , 1990, Physiological reviews.

[87]  R. Miettinen,et al.  Pharmacological consequences of cholinergic plus serotonergic manipulations , 1991, Brain Research.

[88]  L. Záborszky,et al.  Afferents to basal forebrain cholinergic projection neurons: an update. , 1991, Advances in experimental medicine and biology.

[89]  R. Nicoll,et al.  The coupling of neurotransmitter receptors to ion channels in the brain. , 1988, Science.

[90]  E. Azmitia,et al.  Awakening the sleeping giant: anatomy and plasticity of the brain serotonergic system. , 1991, The Journal of clinical psychiatry.

[91]  M. Pontecorvo,et al.  Age-related cognitive impairments as assessed with an automated repeated measures memory task: Implications for the possible role of acetylcholine and norepinephrine in memory dysfunction , 1988, Neurobiology of Aging.

[92]  Y. Sakurai,et al.  The interaction of acetylcholinergic and serotonergic neural systems on performance in a continuous non-matching to sample task , 1990, Brain Research.

[93]  L. Descarries,et al.  Ultrastructural features of the serotonin innervation in adult rat hippocampus: An immunocytochemical description in single and serial thin sections , 1991, Neuroscience.

[94]  I. Whishaw.  Dissociating performance and learning deficits on spatial navigation tasks in rats subjected to cholinergic muscarinic blockade , 1989, Brain Research Bulletin.

[95]  J. Sirviö,et al.  Effects of concurrent nicotinic antagonist and PCPA treatments on spatial and passive avoidance learning , 1992, Brain Research.

[96]  D. Olton,et al.  Comparative cognition and assessment of cognitive processes in animals. , 1992, Behavioural pharmacology.

[97]  D. Olton,et al.  Neurotransmitters and memory: role of cholinergic, serotonergic, and noradrenergic systems. , 1987, Behavioral neuroscience.

[98]  Stephen B. Dunnett,et al.  The basal forebrain-cortical cholinergic system: interpreting the functional consequences of excitotoxic lesions , 1991, Trends in Neurosciences.

[99]  H. Altman,et al.  What is the nature of the role of the serotonergic nervous system in learning and memory: Prospects for development of an effective treatment strategy for senile dementia , 1988, Neurobiology of Aging.

[100]  T. Freund,et al.  GABAergic Interneurons are the Major Postsynaptic Targets of Median Raphe Afferents in the Rat Dentate Gyrus , 1992, The European journal of neuroscience.

[101]  H. Altman,et al.  Effects of combined acetylcholinesterase inhibition and serotonergic receptor blockade on age-associated memory impairments in rats , 1992, Neurobiology of Aging.

[102]  D. Price,et al.  Age-related changes in multiple neurotransmitter systems in the monkey brain , 1989, Neurobiology of Aging.

[103]  B. Jacobs,et al.  Neurophysiological and Neurochemical Studies of Brain Serotonergic Neurons in Behaving Animals a , 1990, Annals of the New York Academy of Sciences.

[104]  J. Blundell,et al.  Serotonin and appetite , 1984, Neuropharmacology.

[105]  M. Carli,et al.  Stimulation of 5-HT1A receptors in the dorsal hippocampus impairs acquisition and performance of a spatial task in a water maze , 1992, Brain Research.

[106]  A. Björklund,et al.  Amelioration of spatial memory impairment by intrahippocampal grafts of mixed septal and raphe tissue in rats with combined cholinergic and serotonergic denervation of the forebrain , 1990, Brain Research.

[107]  P. Jäkälä,et al.  Effects of p-chlorophenylalanine and methysergide on the performance of a working memory task , 1993, Pharmacology Biochemistry and Behavior.

[108]  J. Sirviö,et al.  Brain amines and neocortical EEG in young and aged rats. , 1990, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

[109]  L. Acsády,et al.  The effects of p-chlorophenylalanine-induced serotinin synthesis inhibition and muscarinic blockade on the performance of rats in a 5-choice serial reaction time task , 1992, Behavioural Brain Research.

[110]  A. Levey,et al.  Choline acetyltransferase immunoreactivity in the rat thalamus , 1987, The Journal of comparative neurology.

[111]  G. Wardeh,et al.  Muscarine receptor-mediated modulation of [3H]dopamine and [14C]acetylcholine release from rat neostriatal slices: selective antagonism by gallamine but not pirenzepine. , 1986, European journal of pharmacology.

[112]  L. Acsády,et al.  Serotonergic control of the hippocampus via local inhibitory interneurons. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[113]  B. Jacobs,et al.  Structure and function of the brain serotonin system. , 1992, Physiological reviews.

[114]  S. Robinson.  Effect of specific serotonergic lesions on cholinergic neurons in the hippocampus, cortex and striatum. , 1983, Life sciences.

[115]  L. Ferraro,et al.  Effect of nicotine on the release of acetylcholine and amino acids in the brain. , 1989, Progress in brain research.

[116]  B. Costall,et al.  5-HT3 receptors mediate inhibition of acetylcholine release in cortical tissue , 1989, Nature.

[117]  J L McGaugh,et al.  The role of interactions between the cholinergic system and other neuromodulatory systems in learing and memory , 1991, Synapse.

[118]  C. H. Vanderwolf,et al.  Serotonergic Control of Cerebral Activity and Behavior: Models of Dementia , 1990, Annals of the New York Academy of Sciences.

[119]  T. Bonner.  The molecular basis of muscarinic receptor diversity , 1989, Trends in Neurosciences.

[120]  D. McCormick.  Cholinergic and noradrenergic modulation of thalamocortical processing , 1989, Trends in Neurosciences.

[121]  Y. Minabe,et al.  5-HT3-like receptors in the rat medial prefrontal cortex: an electrophysiological study , 1991, Brain Research.

[122]  Joseph B. Martin,et al.  Neuropeptides in neurological disease , 1986, Annals of neurology.

[123]  M. Molliver,et al.  Dual serotoninergic projections to forebrain in the rat: Morphologically distinct 5‐HT axon terminals exhibit differential vulnerability to neurotoxic amphetamine derivatives , 1991, The Journal of comparative neurology.

[124]  F. Hery,et al.  In vivo evidence for acetylcholine control of serotonin release in the cat caudate nucleus: influence of halothane anaesthesia , 1988, Neuroscience.

[125]  M. Segal,et al.  Spatial performance is severely impaired in rats with combined reduction of serotonergic and cholinergic transmission , 1989, Brain Research.

[126]  V. Gribkoff,et al.  Relationship between performance in the morris water task, visual acuity, and thermoregulatory function in aged F-344 rats , 1991, Behavioural Brain Research.

[127]  R. Berman,et al.  The effects of p-chloroamphetamine, a depletor of brain serotonin, on the performance of rats in two types of positively reinforced complex spatial discrimination tasks. , 1989, Behavioral and neural biology.

[128]  A. Cross.  Serotonin in Alzheimer‐type Dementia and Other Dementing Illnesses , 1990, Annals of the New York Academy of Sciences.

[129]  J. Bruno,et al.  Inhibition of striatal acetylcholine release by serotonin and dopamine after the intracerebral administration of 6-hydroxydopamine to neonatal rats , 1988, Brain Research.

[130]  M. Pangalos,et al.  5-Hydroxytryptamine1A but not 5-hydroxytryptamine2 receptors are enriched on neocortical pyramidal neurones destroyed by intrastriatal volkensin. , 1992, The Journal of pharmacology and experimental therapeutics.

[131]  C. H. Vanderwolf,et al.  Serotonin-dependent cerebral activation: effects of methiothepin and other serotonergic antagonists , 1992, Brain Research.

[132]  T. Reader,et al.  [3H]Paroxetine Binding and Serotonin Content of Rat Cortical Areas, Hippocampus, Neostriatum, Ventral Mesencephalic Tegmentum, and Midbrain Raphe Nuclei Region Following p‐Chlorophenylalanine and p‐Chloroamphetamine Treatment , 1992, Journal of neurochemistry.

[133]  P. Solomon,et al.  Differential effects of lesions in medial and dorsal raphe of the rat: latent inhibition and septohippocampal serotonin levels. , 1980, Journal of comparative and physiological psychology.

[134]  C. H. Vanderwolf.  A general role for serotonin in the control of behavior: studies with intracerebral 5,7-dihydroxytryptamine , 1989, Brain Research.

[135]  G. Rose,et al.  Age-related reduction in responses of rat hippocampal neurons to locally applied monoamines , 1988, Neurobiology of Aging.

[136]  A. R. Damasio,et al.  Memory‐related neural systems in Alzheimer's disease , 1990, Neurology.

[137]  S B Dunnett,et al.  Role of prefrontal cortex and striatal output systems in short-term memory deficits associated with ageing, basal forebrain lesions, and cholinergic-rich grafts. , 1990, Canadian journal of psychology.

[138]  G. Buzsáki,et al.  Nucleus basalis and thalamic control of neocortical activity in the freely moving rat , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[139]  E. Meyer,et al.  Pharmacological and ionic characterizations of the muscarinic receptors modulating [3H]acetylcholine release from rat cortical synaptosomes , 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[140]  L. Beani,et al.  5‐HT1A agonists increase and 5‐HT3 agonists decrease acetylcholine efflux from the cerebral cortex of freely‐moving guinea‐pigs , 1990, British journal of pharmacology.

[141]  B. Costall,et al.  The effects of ondansetron, a 5-HT3 receptor antagonist, on cognition in rodents and primates , 1990, Pharmacology Biochemistry and Behavior.

[142]  Anne W. Schmidt,et al.  Serotonin Receptor “Families” in the Central Nervous System: An Overview a , 1990, Annals of the New York Academy of Sciences.

[143]  C. H. Vanderwolf,et al.  The role of serotonin in the control of cerebral activity: studies with intracerebral 5,7-dihydroxytryptamine , 1989, Brain Research.

[144]  G. Buzsáki,et al.  The cholinergic system and EEG slow waves. , 1991, Electroencephalography and clinical neurophysiology.