Distinct pattern of enteric phospho-alpha-synuclein aggregates and gene expression profiles in patients with Parkinson’s disease
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G. Deuschl | S. Schneider | T. Wedel | C. Lange | M. Ellrichmann | M. Böttner | F. Cossais | M. Barrenschee | D. Zorenkov | A. Fritscher-Ravens | A. Scharf
[1] S. Hamilton-Dutoit,et al. Pathological α‐synuclein in gastrointestinal tissues from prodromal Parkinson disease patients , 2016, Annals of neurology.
[2] L. Leclair-Visonneau,et al. What a gastrointestinal biopsy can tell us about Parkinson's disease? , 2016, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[3] G. Deuschl,et al. Can we use peripheral tissue biopsies to diagnose Parkinson's disease? A review of the literature , 2016, European journal of neurology.
[4] H. Reichmann,et al. Pathogenesis of Parkinson disease—the gut–brain axis and environmental factors , 2015, Nature Reviews Neurology.
[5] E. Tolosa,et al. Alpha-synuclein immunoreactivity patterns in the enteric nervous system , 2015, Neuroscience Letters.
[6] Yun Li,et al. Alteration of enteric monoamines with monoamine receptors and colonic dysmotility in 6-hydroxydopamine-induced Parkinson's disease rats. , 2015, Translational research : the journal of laboratory and clinical medicine.
[7] K. Jellinger. Neuropathobiology of non-motor symptoms in Parkinson disease , 2015, Journal of Neural Transmission.
[8] M. Cersosimo. Gastrointestinal Biopsies for the Diagnosis of Alpha-Synuclein Pathology in Parkinson's Disease , 2015, Gastroenterology research and practice.
[9] M. Heymann,et al. Structural alterations of the intestinal epithelial barrier in Parkinson’s disease , 2015, Acta neuropathologica communications.
[10] L. Hazrati,et al. Colonic mucosal α-synuclein lacks specificity as a biomarker for Parkinson disease , 2015, Neurology.
[11] T. Südhof,et al. α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation , 2014, Proceedings of the National Academy of Sciences.
[12] J. Blaivas,et al. A Review of Lower Urinary Tract Symptoms in Patients with Parkinson’s Disease , 2014, Current Urology Reports.
[13] M. Catalán,et al. In vivo gastric detection of α‐synuclein inclusions in Parkinson's disease , 2015, Movement disorders : official journal of the Movement Disorder Society.
[14] C. Carroll,et al. Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson’s disease , 2014, Acta Neuropathologica.
[15] Jiajie Diao,et al. Properties of native brain α-synuclein , 2013, Nature.
[16] Hitoshi Takahashi,et al. The Lewy Body in Parkinson’s Disease and Related Neurodegenerative Disorders , 2013, Molecular Neurobiology.
[17] D. Devos,et al. Colonic inflammation in Parkinson's disease , 2013, Neurobiology of Disease.
[18] D. Munoz,et al. Enteric alpha‐synuclein expression is increased in Parkinson's disease but not Alzheimer's disease , 2013, Movement disorders : official journal of the Movement Disorder Society.
[19] G. Deuschl,et al. Expression pattern and localization of alpha-synuclein in the human enteric nervous system , 2012, Neurobiology of Disease.
[20] H. Reichmann,et al. Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice , 2012, Scientific Reports.
[21] C. Adler,et al. Parkinson’s disease is not associated with gastrointestinal myenteric ganglion neuron loss , 2012, Acta Neuropathologica.
[22] T. Outeiro,et al. Alpha-synuclein: from secretion to dysfunction and death , 2012, Cell Death and Disease.
[23] Kevin W Eliceiri,et al. NIH Image to ImageJ: 25 years of image analysis , 2012, Nature Methods.
[24] John B. Furness,et al. The enteric nervous system and neurogastroenterology , 2012, Nature Reviews Gastroenterology &Hepatology.
[25] H. Takayama,et al. Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice , 2012, Laboratory Investigation.
[26] Lisheng Li,et al. Dopamine receptor D1 mediates the inhibition of dopamine on the distal colonic motility. , 2012, Translational research : the journal of laboratory and clinical medicine.
[27] K. Shannon,et al. Alpha‐synuclein in colonic submucosa in early untreated Parkinson's disease , 2012, Movement disorders : official journal of the Movement Disorder Society.
[28] S. B. des Varannes,et al. A comparison between colonic submucosa and mucosa to detect Lewy pathology in Parkinson’s disease , 2012, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[29] O. Suchowersky,et al. Increased Intestinal Permeability and Parkinson Disease Patients: Chicken or Egg? , 2012, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.
[30] L. Stefanis. α-Synuclein in Parkinson's disease. , 2012, Cold Spring Harbor perspectives in medicine.
[31] M. Jönsson,et al. Epithelial Expression of Vasoactive Intestinal Peptide in Ulcerative Colitis: Down-Regulation in Markedly Inflamed Colon , 2012, Digestive Diseases and Sciences.
[32] M. Neunlist,et al. A comparison between rectal and colonic biopsies to detect Lewy pathology in Parkinson's disease , 2012, Neurobiology of Disease.
[33] K. Jellinger. Neuropathology of sporadic Parkinson's disease: Evaluation and changes of concepts , 2012, Movement disorders : official journal of the Movement Disorder Society.
[34] Jeffrey H. Kordower,et al. Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease , 2011, PloS one.
[35] K. Lyons,et al. The impact and management of nonmotor symptoms of Parkinson's disease. , 2011, The American journal of managed care.
[36] K. Krogh. Gastrointestinal Dysfunction in Parkinson’s Disease , 2011 .
[37] D. Selkoe,et al. α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation , 2011, Nature.
[38] M. Gershon. Developmental determinants of the independence and complexity of the enteric nervous system , 2010, Trends in Neurosciences.
[39] P. Damier,et al. Colonic Biopsies to Assess the Neuropathology of Parkinson's Disease and Its Relationship with Symptoms , 2010, PloS one.
[40] W. Meier-Ruge,et al. The London Classification of gastrointestinal neuromuscular pathology: report on behalf of the Gastro 2009 International Working Group , 2010, Gut.
[41] Johannes C. Klein,et al. Neurotransmitter changes in dementia with Lewy bodies and Parkinson disease dementia in vivo , 2010, Neurology.
[42] H. Reichmann,et al. Progression of Parkinson's Disease Pathology Is Reproduced by Intragastric Administration of Rotenone in Mice , 2010, PloS one.
[43] E. Bézard,et al. Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms , 2009, The Lancet Neurology.
[44] Thomas Gasser,et al. Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria , 2009, The Lancet Neurology.
[45] S. B. des Varannes,et al. Routine colonic biopsies as a new tool to study the enteric nervous system in living patients , 2009, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[46] Takuya Suzuki,et al. PKCη regulates occludin phosphorylation and epithelial tight junction integrity , 2009, Proceedings of the National Academy of Sciences.
[47] P. Damier,et al. Pathological lesions in colonic biopsies during Parkinson’s disease , 2008, Gut.
[48] C. Adler,et al. Evaluation of α-synuclein immunohistochemical methods used by invited experts , 2008, Acta Neuropathologica.
[49] T. Powley,et al. Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: Autonomic pathway implicated in Parkinson's disease? , 2008, Neuroscience.
[50] J. Furness,et al. The enteric nervous system: normal functions and enteric neuropathies , 2008, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[51] J. Jankovic,et al. Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Process, format, and clinimetric testing plan , 2007, Movement disorders : official journal of the Movement Disorder Society.
[52] M. Perdue,et al. Muscarinic acetylcholine receptor activation increases transcellular transport of macromolecules across mouse and human intestinal epithelium in vitro , 2007, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[53] R. Barbour,et al. Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease* , 2006, Journal of Biological Chemistry.
[54] R. Nussbaum,et al. Levels of alpha‐synuclein mRNA in sporadic Parkinson disease patients , 2006, Movement disorders : official journal of the Movement Disorder Society.
[55] Jochen Klucken,et al. Detection of novel intracellular O‐synuclein oligomeric species by fluorescence lifetime imaging , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[56] A. Probst,et al. α‐Synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects , 2006, Neuropathology and applied neurobiology.
[57] H. Braak,et al. Gastric α-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology , 2006, Neuroscience Letters.
[58] C. Shults. Lewy bodies. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[59] Yi Zhao,et al. Alpha‐synuclein mRNA expression in sporadic Parkinson's disease , 2005, Movement disorders : official journal of the Movement Disorder Society.
[60] M. Neunlist,et al. The human enteric nervous system , 2004, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[61] A. Lees,et al. Alteration in α‐synuclein mRNA expression in Parkinson's disease , 2004 .
[62] K. Murthy,et al. Erk1/2- and p38 MAP kinase-dependent phosphorylation and activation of cPLA2 by m3 and m2 receptors. , 2003, American journal of physiology. Gastrointestinal and liver physiology.
[63] A. Fasano,et al. Gastrointestinal dysfunction in Parkinson's disease , 2003, The Lancet Neurology.
[64] S. Hirai,et al. Heterogeneity of Nigral and Cortical Lewy Bodies Differentiated by Amplified Triple-Labeling for Alpha-Synuclein, Ubiquitin, and Thiazin Red , 2002, Experimental Neurology.
[65] T. Chase,et al. Muscarinic Receptor Stimulation Induces Translocation of an α-Synuclein Oligomer from Plasma Membrane to a Light Vesicle Fraction in Cytoplasm* , 2001, The Journal of Biological Chemistry.
[66] S. Brookes,et al. Anatomy and physiology of the enteric nervous system , 2000, Gut.
[67] B. Hyman,et al. α-Synuclein immunoreactivity in dementia with Lewy bodies: morphological staging and comparison with ubiquitin immunostaining , 2000, Acta Neuropathologica.
[68] P. Andrews,et al. Fundamentals of neurogastroenterology , 1999, Gut.
[69] W. Kühnel,et al. Organization of the enteric nervous system in the human colon demonstrated by wholemount immunohistochemistry with special reference to the submucous plexus. , 1999, Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft.
[70] S. Wexner,et al. A constipation scoring system to simplify evaluation and management of constipated patients , 1996, Diseases of the colon and rectum.
[71] G. Burnstock,et al. Vasoactive intestinal polypeptide levels in sigmoid colon in idiopathic constipation and diverticular disease. , 1990, Gastroenterology.
[72] Xiao-ying Jiang,et al. Effects of enteral nutrition on the barrier function of the intestinal mucosa and dopamine receptor expression in rats with traumatic brain injury. , 2015, JPEN. Journal of parenteral and enteral nutrition.
[73] J. Woulfe,et al. Colonic mucosal α-synuclein lacks specificity as a biomarker for Parkinson disease. , 2015, Neurology.
[74] J. Dorszewska,et al. [Alpha-synuclein in Parkinson's disease]. , 2014, Przeglad lekarski.
[75] Jing-Jing Wei,et al. The 5-HT4 receptor agonist mosapride attenuates inflammation of reflux esophagitis. , 2014, Hepato-Gastroenterology.
[76] R Core Team,et al. R: A language and environment for statistical computing. , 2014 .
[77] M. Matsui,et al. M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum: Findings obtained with muscarinic-receptor knockout mouse. , 2007, American journal of physiology. Gastrointestinal and liver physiology.
[78] A. Lees,et al. Alteration in alpha-synuclein mRNA expression in Parkinson's disease. , 2004, Movement disorders : official journal of the Movement Disorder Society.
[79] S. Holm. A Simple Sequentially Rejective Multiple Test Procedure , 1979 .