Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase.

[1]  Michael Stoker,et al.  Scatter factor is a fibroblast-derived modulator of epithelial cell mobility , 1987, Nature.

[2]  L. Naldini,et al.  RON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP. , 1994, The EMBO journal.

[3]  G. Michalopoulos,et al.  Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA. , 1993, The American journal of pathology.

[4]  Carmen Birchmeier,et al.  Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud , 1995, Nature.

[5]  K. Miyazawa,et al.  Activation of hepatocyte growth factor by proteolytic conversion of a single chain form to a heterodimer. , 1992, The Journal of biological chemistry.

[6]  M. Sharpe,et al.  Scatter factor/hepatocyte growth factor is essential for liver development , 1995, Nature.

[7]  M. Okigaki,et al.  Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor. , 1989, Biochemical and biophysical research communications.

[8]  A. Bardelli,et al.  A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family , 1994, Cell.

[9]  K. Matsumoto,et al.  Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development. , 1998, Development.

[10]  T. Blundell,et al.  Molecular evolution and domain structure of plasminogen‐related growth factors (HGF/SF and HGF1/MSP) , 1994, Protein science : a publication of the Protein Society.

[11]  C. Cooper,et al.  Mechanism of met oncogene activation , 1986, Cell.

[12]  M. Nagao,et al.  A fibroblast-derived tumor cytotoxic factor/F-TCF (hepatocyte growth factor/HGF) has multiple functions in vitro. , 1991, Cell biology international reports.

[13]  S. J. Degen,et al.  Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor. , 1991, Biochemistry.

[14]  K. Matsumoto,et al.  Purification and Cloning of Hepatocyte Growth Factor Activator Inhibitor Type 2, a Kunitz-type Serine Protease Inhibitor* , 1997, The Journal of Biological Chemistry.

[15]  M. Hanson,et al.  Hepatocyte Growth Factor/Scatter Factor Is an Axonal Chemoattractant and a Neurotrophic Factor for Spinal Motor Neurons , 1996, Neuron.

[16]  K. Bauer,et al.  Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2 , 1996, The Journal of cell biology.

[17]  R. Lovell-Badge,et al.  Preventing the loss of competence for neural induction: HGF/SF, L5 and Sox-2. , 1997, Development.

[18]  K. Miyazawa,et al.  Activation of the zymogen of hepatocyte growth factor activator by thrombin. , 1993, The Journal of biological chemistry.

[19]  M. Goulding,et al.  Pax-3 is necessary for migration but not differentiation of limb muscle precursors in the mouse. , 1996, Development.

[20]  Richard G. Taylor,et al.  Hepatocyte growth factor activates quiescent skeletal muscle satellite cells in vitro , 1995, Journal of cellular physiology.

[21]  M. Noble,et al.  Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros , 1995, The Journal of cell biology.

[22]  K. Matsumoto,et al.  Hepatocyte growth factor is involved in the morphogenesis of tooth germ in murine molars. , 1996, Development.

[23]  A. Bardelli,et al.  Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2 , 1997, Oncogene.

[24]  W. Birchmeier,et al.  Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. , 1992, The EMBO journal.

[25]  H. Arnold,et al.  Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells. , 1994, Development.

[26]  T. Braun,et al.  Regulation and function of SF/HGF during migration of limb muscle precursor cells in chicken. , 1996, Developmental biology.

[27]  E. Appella,et al.  Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity , 1991, The Journal of experimental medicine.

[28]  E. Gherardi,et al.  Epithelial scatter factor and development of the chick embryonic axis. , 1990, Development.

[29]  A. Davies,et al.  Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons. , 1997, Genes & development.

[30]  A. Bardelli,et al.  Induction of epithelial tubules by growth factor HGF depends on the STAT pathway , 1998, Nature.

[31]  K. Vogan,et al.  Expression of the met receptor tyrosine kinase in muscle progenitor cells in somites and limbs is absent in Splotch mice. , 1996, Development.

[32]  D Lamba,et al.  The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator. , 1996, Journal of molecular biology.

[33]  L. Orci,et al.  Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor , 1991, Cell.

[34]  P. Comoglio,et al.  Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells , 1995, Molecular and cellular biology.

[35]  Morag Park,et al.  Hepatocyte Growth Factor-induced Scatter of Madin-Darby Canine Kidney Cells Requires Phosphatidylinositol 3-Kinase (*) , 1995, The Journal of Biological Chemistry.

[36]  K. Matsumoto,et al.  Activation of Met tyrosine kinase by hepatocyte growth factor is essential for internal organogenesis in Xenopus embryo. , 1997, Biochemical and biophysical research communications.

[37]  W. Birchmeier,et al.  Characterization of the Scatter Factor/Hepatocyte Growth Factor Gene Promoter , 1995, The Journal of Biological Chemistry.

[38]  M. Park,et al.  Expression of the met/hepatocyte growth factor/scatter factor receptor and its ligand during differentiation of murine P19 embryonal carcinoma cells. , 1993, Developmental biology.

[39]  G. Michalopoulos,et al.  Hepatocyte growth factor is a mitogen for Schwann cells and is present in neurofibromas , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[40]  O. Sthandier,et al.  A Natural Hepatocyte Growth Factor/Scatter Factor Autocrine Loop in Myoblast Cells and the Effect of the Constitutive Met Kinase Activation on Myogenic Differentiation , 1997, The Journal of cell biology.

[41]  C. Birchmeier,et al.  Scatter factor/hepatocyte growth factor (SF/HGF) induces emigration of myogenic cells at interlimb level in vivo. , 1996, Developmental biology.

[42]  A. Simeone,et al.  Uncoupling of Grb2 from the Met Receptor In Vivo Reveals Complex Roles in Muscle Development , 1996, Cell.

[43]  J. Livet,et al.  Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons. , 1997, Development.

[44]  C. Birchmeier,et al.  Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development , 1993, The Journal of cell biology.

[45]  A. Bardelli,et al.  Specific Uncoupling of GRB2 from the Met Receptor , 1996, The Journal of Biological Chemistry.

[46]  E. Leonard,et al.  Identification of the ron gene product as the receptor for the human macrophage stimulating protein. , 1994, Science.

[47]  Tetsuo Noda,et al.  Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor , 1995, Nature.

[48]  J. Rubin,et al.  Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. , 1991, Science.

[49]  K. Tashiro,et al.  Molecular cloning and expression of human hepatocyte growth factor , 1989, Nature.

[50]  W. Birchmeier,et al.  Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo , 1998, Current Biology.

[51]  W. Birchmeier,et al.  Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland , 1995, The Journal of cell biology.

[52]  W. Birchmeier,et al.  Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis , 1996, Nature.

[53]  A. Davies,et al.  Multiple Roles for Hepatocyte Growth Factor in Sympathetic Neuron Development , 1998, Neuron.