Difference in the relative biological effectiveness and DNA damage repair processes in response to proton beam therapy according to the positions of the spread out Bragg peak

[1]  A. Matsuda,et al.  A Nucleoside Anticancer Drug, 1-(3-C-Ethynyl-β-D-Ribo-Pentofuranosyl)Cytosine, Induces Depth-Dependent Enhancement of Tumor Cell Death in Spread-Out Bragg Peak (SOBP) of Proton Beam , 2016, PloS one.

[2]  Y. Shibamoto,et al.  Spot Scanning and Passive Scattering Proton Therapy: Relative Biological Effectiveness and Oxygen Enhancement Ratio in Cultured Cells. , 2016, International journal of radiation oncology, biology, physics.

[3]  P. Chaudhary,et al.  Variations in the Processing of DNA Double-Strand Breaks Along 60-MeV Therapeutic Proton Beams , 2016, International journal of radiation oncology, biology, physics.

[4]  Shikui Tang,et al.  Proton beam radiation therapy results in significantly reduced toxicity compared with intensity-modulated radiation therapy for head and neck tumors that require ipsilateral radiation. , 2016, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[5]  Tatsuya Nakamura,et al.  Preliminary treatment results of proton beam therapy with chemoradiotherapy for stage I–III esophageal cancer , 2016, Cancer medicine.

[6]  Matthias Guckenberger,et al.  Differential DNA repair pathway choice in cancer cells after proton- and photon-irradiation. , 2015, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[7]  A. Campa,et al.  Induction and Repair of DNA DSB as Revealed by H2AX Phosphorylation Foci in Human Fibroblasts Exposed to Low- and High-LET Radiation: Relationship with Early and Delayed Reproductive Cell Death , 2015, Radiation research.

[8]  Marco Durante,et al.  Proton Radiobiology , 2015, Cancers.

[9]  H. Paganetti,et al.  Radiobiological Intercomparison of the 160 MeV and 230 MeV Proton Therapy Beams at the Harvard Cyclotron Laboratory and at Massachusetts General Hospital , 2015, Radiation research.

[10]  Harald Paganetti,et al.  Relative biological effectiveness (RBE) values for proton beam therapy. Variations as a function of biological endpoint, dose, and linear energy transfer , 2014, Physics in medicine and biology.

[11]  Giuseppe Schettino,et al.  Relative biological effectiveness variation along monoenergetic and modulated Bragg peaks of a 62-MeV therapeutic proton beam: a preclinical assessment. , 2014, International journal of radiation oncology, biology, physics.

[12]  D. Biard,et al.  Involvement of the Artemis protein in the relative biological efficiency observed with the 76-MeV proton beam used at the Institut Curie Proton Therapy Center in Orsay. , 2014, International journal of radiation oncology, biology, physics.

[13]  T. Sakae,et al.  RBE and OER within the spread-out Bragg peak for proton beam therapy: in vitro study at the Proton Medical Research Center at the University of Tsukuba , 2014, Journal of radiation research.

[14]  H. Ishikawa,et al.  High-dose concurrent chemo–proton therapy for Stage III NSCLC: preliminary results of a Phase II study , 2014, Journal of radiation research.

[15]  Y. Matsumoto,et al.  Enhanced radiobiological effects at the distal end of a clinical proton beam: in vitro study , 2014, Journal of radiation research.

[16]  Irene L. Ibañez,et al.  Induction and persistence of large γH2AX foci by high linear energy transfer radiation in DNA-dependent protein kinase-deficient cells. , 2013, International journal of radiation oncology, biology, physics.

[17]  A. Nakamura,et al.  Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer research. , 2012, Cancer letters.

[18]  R. Mohan,et al.  Proton beam therapy and concurrent chemotherapy for esophageal cancer. , 2012, International journal of radiation oncology, biology, physics.

[19]  T. Hashimoto,et al.  Results of Proton Beam Therapy without Concurrent Chemotherapy for Patients with Unresectable Stage III Non-small Cell Lung Cancer , 2012, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[20]  V. Favaudon,et al.  Radiobiological characterization of two therapeutic proton beams with different initial energy spectra used at the Institut Curie Proton Therapy Center in Orsay. , 2011, International journal of radiation oncology, biology, physics.

[21]  Joe Y. Chang,et al.  Phase 2 study of high‐dose proton therapy with concurrent chemotherapy for unresectable stage III nonsmall cell lung cancer , 2011, Cancer.

[22]  P. Olive,et al.  Retention of γH2AX foci as an indication of lethal DNA damage. , 2011, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[23]  G. Cuttone,et al.  Response of a radioresistant human melanoma cell line along the proton spread-out Bragg peak , 2010, International journal of radiation biology.

[24]  Markus Löbrich,et al.  γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization , 2010, Cell cycle.

[25]  Stephen J Kron,et al.  Histone H2AX Phosphorylation as a Predictor of Radiosensitivity and Target for Radiotherapy* , 2004, Journal of Biological Chemistry.

[26]  Uwe Oelfke,et al.  Analytical linear energy transfer calculations for proton therapy. , 2003, Medical physics.

[27]  Harald Paganetti,et al.  Relative biological effectiveness (RBE) values for proton beam therapy. , 2002, International journal of radiation oncology, biology, physics.

[28]  H Paganetti,et al.  Calculation of relative biological effectiveness for proton beams using biological weighting functions. , 1997, International journal of radiation oncology, biology, physics.

[29]  C. Keppel,et al.  Variations in the RBE for Cell Killing Along the Depth-Dose Profile of a Modulated Proton Therapy Beam , 2013, Radiation research.

[30]  H. Saitoh,et al.  Relation between lineal energy distribution and relative biological effectiveness for photon beams according to the microdosimetric kinetic model. , 2011, Journal of radiation research.

[31]  Kai Rothkamm,et al.  gamma-H2AX as protein biomarker for radiation exposure. , 2009, Annali dell'Istituto superiore di sanita.