Poly(ADP-ribose) polymerase 1 accelerates vascular calcification by upregulating Runx2

[1]  L. Rubbia‐Brandt,et al.  Editorial: Tumor Heterogeneity , 2019, Front. Med..

[2]  Kai Huang,et al.  CTRP13 inhibits atherosclerosis via autophagy‐lysosome‐dependent degradation of CD36 , 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[3]  Yanqing Zhang,et al.  Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity , 2018, Cell Death & Disease.

[4]  Kai Huang,et al.  A20 prevents obesity-induced development of cardiac dysfunction , 2017, Journal of Molecular Medicine.

[5]  M. Hayashi,et al.  Smooth Muscle–Selective Nuclear Factor‐κB Inhibition Reduces Phosphate‐Induced Arterial Medial Calcification in Mice With Chronic Kidney Disease , 2017, Journal of the American Heart Association.

[6]  Joshua D. Hutcheson,et al.  Giving Calcification Its Due: Recognition of a Diverse Disease: A First Attempt to Standardize the Field. , 2017, Circulation research.

[7]  Shi-You Chen,et al.  Olfactomedin 2 Regulates Smooth Muscle Phenotypic Modulation and Vascular Remodeling Through Mediating Runt-Related Transcription Factor 2 Binding to Serum Response Factor , 2017, Arteriosclerosis, thrombosis, and vascular biology.

[8]  Kai Huang,et al.  Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury. , 2016, The American journal of pathology.

[9]  M. Wallingford,et al.  Runx2 deletion in smooth muscle cells inhibits vascular osteochondrogenesis and calcification but not atherosclerotic lesion formation. , 2016, Cardiovascular research.

[10]  R. Kuiper,et al.  Analyzing structure–function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells , 2016, Nucleic acids research.

[11]  Jamin D Steffen,et al.  PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain. , 2015, Molecular cell.

[12]  W. Kong,et al.  Mammalian target of rapamycin signaling inhibition ameliorates vascular calcification via Klotho upregulation. , 2015, Kidney international.

[13]  C. Giachelli,et al.  Runx2 Expression in Smooth Muscle Cells Is Required for Arterial Medial Calcification in Mice. , 2015, The American journal of pathology.

[14]  F. Bock,et al.  Stress response: PARP1 911. , 2015, Nature chemical biology.

[15]  Su‐Li Cheng,et al.  Targeted Reduction of Vascular Msx1 and Msx2 Mitigates Arteriosclerotic Calcification and Aortic Stiffness in LDLR-Deficient Mice Fed Diabetogenic Diets , 2014, Diabetes.

[16]  C. St. Hilaire,et al.  Medial vascular calcification revisited: review and perspectives. , 2014, European heart journal.

[17]  R. Martínez-Zamudio,et al.  PARP1 enhances inflammatory cytokine expression by alteration of promoter chromatin structure in microglia , 2014, Brain and behavior.

[18]  J. DiNicolantonio,et al.  The Molecular Biology and Pathophysiology of Vascular Calcification , 2014, Postgraduate medicine.

[19]  C. Couture,et al.  Role for DNA Damage Signaling in Pulmonary Arterial Hypertension , 2014, Circulation.

[20]  X. Wan,et al.  A TrkB–STAT3–miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells , 2013, Molecular Cancer.

[21]  M. Chonchol,et al.  Vascular calcification in end‐stage renal disease , 2013, Hemodialysis international. International Symposium on Home Hemodialysis.

[22]  Kai Huang,et al.  Poly(ADP-Ribose) Polymerase 1 Promotes Oxidative-Stress-Induced Liver Cell Death via Suppressing Farnesoid X Receptor α , 2013, Molecular and Cellular Biology.

[23]  Kai Huang,et al.  Inhibition of PARP prevents angiotensin II-induced aortic fibrosis in rats. , 2013, International journal of cardiology.

[24]  J. Erdmann,et al.  Functional interaction of osteogenic transcription factors Runx2 and Vdr in transcriptional regulation of Opn during soft tissue calcification. , 2013, The American journal of pathology.

[25]  Wei Zhu,et al.  Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release. , 2013, Kidney international.

[26]  I. Drozdov,et al.  Prelamin A Accelerates Vascular Calcification Via Activation of the DNA Damage Response and Senescence-Associated Secretory Phenotype in Vascular Smooth Muscle Cells , 2013, Circulation research.

[27]  C. Shanahan,et al.  Mechanistic insights into vascular calcification in CKD. , 2013, Journal of the American Society of Nephrology : JASN.

[28]  L. Virág,et al.  Role of poly(ADP‐ribose) polymerases in the regulation of inflammatory processes , 2012, FEBS letters.

[29]  Yong Sun,et al.  Smooth Muscle Cell–Specific Runx2 Deficiency Inhibits Vascular Calcification , 2012, Circulation research.

[30]  Fengli Wang,et al.  The role of PARP1 in the DNA damage response and its application in tumor therapy , 2012, Frontiers of Medicine.

[31]  J. Pascal,et al.  Structural Basis for DNA Damage–Dependent Poly(ADP-ribosyl)ation by Human PARP-1 , 2012, Science.

[32]  K. Caidahl,et al.  Increased transcript level of poly(ADP-ribose) polymerase (PARP-1) in human tricuspid compared with bicuspid aortic valves correlates with the stenosis severity. , 2012, Biochemical and biophysical research communications.

[33]  T. Yoneda,et al.  Regulation of bone and cartilage development by network between BMP signalling and transcription factors. , 2012, Journal of biochemistry.

[34]  W. Kraus,et al.  On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1. , 2012, Genes & development.

[35]  G. M. Wilson,et al.  Activation of nuclear factor-kappa B accelerates vascular calcification by inhibiting progressive ankylosis protein homolog expression , 2012, Kidney international.

[36]  K. Fujisaki,et al.  The antioxidant tempol ameliorates arterial medial calcification in uremic rats: Important role of oxidative stress in the pathogenesis of vascular calcification in chronic kidney disease , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[37]  C. Shanahan,et al.  Arterial Calcification in Chronic Kidney Disease: Key Roles for Calcium and Phosphate , 2011, Circulation research.

[38]  G. Stein,et al.  A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2 , 2011, Proceedings of the National Academy of Sciences.

[39]  Z. Al‐Aly Phosphate, oxidative stress, and nuclear factor-κB activation in vascular calcification. , 2011, Kidney international.

[40]  W. Kong,et al.  Mitochondrial reactive oxygen species promote p65 nuclear translocation mediating high-phosphate-induced vascular calcification in vitro and in vivo. , 2011, Kidney international.

[41]  Qingbo Xu,et al.  Cartilage Oligomeric Matrix Protein Inhibits Vascular Smooth Muscle Calcification by Interacting With Bone Morphogenetic Protein-2 , 2011, Circulation research.

[42]  E. Paquet,et al.  The Journal of Experimental Medicine CORRESPONDENCE , 2005 .

[43]  H. Ryoo,et al.  BMP2-activated Erk/MAP Kinase Stabilizes Runx2 by Increasing p300 Levels and Histone Acetyltransferase Activity* , 2010, The Journal of Biological Chemistry.

[44]  P. D’Haese,et al.  Chondrocyte Rather Than Osteoblast Conversion of Vascular Cells Underlies Medial Calcification in Uremic Rats , 2010, Arteriosclerosis, thrombosis, and vascular biology.

[45]  Kai Huang,et al.  Activation and overexpression of PARP-1 in circulating mononuclear cells promote TNF-alpha and IL-6 expression in patients with unstable angina. , 2008, Archives of medical research.

[46]  Yin Tintut,et al.  Vascular calcification: pathobiology of a multifaceted disease. , 2008, Circulation.

[47]  J. Kappes,et al.  Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling* , 2008, Journal of Biological Chemistry.

[48]  L. Demer Pathobiology of a Multifaceted Disease , 2008 .

[49]  C. Szabó,et al.  Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors. , 2007, Cardiovascular drug reviews.

[50]  V. Schreiber,et al.  Poly(ADP-ribose): novel functions for an old molecule , 2006, Nature Reviews Molecular Cell Biology.

[51]  Janet L Stein,et al.  Canonical WNT Signaling Promotes Osteogenesis by Directly Stimulating Runx2 Gene Expression* , 2005, Journal of Biological Chemistry.

[52]  Csaba Szabó,et al.  Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors , 2005, Nature Reviews Drug Discovery.

[53]  J. Westendorf,et al.  Histone Deacetylase 3 Interacts with Runx2 to Repress the Osteocalcin Promoter and Regulate Osteoblast Differentiation* , 2004, Journal of Biological Chemistry.

[54]  N. Vaziri Oxidative stress in uremia: nature, mechanisms, and potential consequences. , 2004, Seminars in nephrology.

[55]  J. Edwards,et al.  Vascular biology in uremia: insights into novel mechanisms of vascular injury. , 2004, Advances in chronic kidney disease.

[56]  E. Schwarz,et al.  Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes , 2003, Journal of cellular biochemistry.

[57]  J. Himmelfarb,et al.  Oxidative stress in uremia , 2003, Current opinion in nephrology and hypertension.

[58]  N. Vaziri,et al.  Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency. , 2003, Kidney international.

[59]  R. Aebersold,et al.  Smooth Muscle Cell Phenotypic Transition Associated With Calcification: Upregulation of Cbfa1 and Downregulation of Smooth Muscle Lineage Markers , 2001, Circulation research.

[60]  M. Hottiger,et al.  A Role of Poly (ADP-Ribose) Polymerase in NF- B Transcriptional Activation , 1999 .

[61]  M. Hottiger,et al.  A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation. , 1999, Biological chemistry.