SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of β1-integrin

[1]  Erik Sahai,et al.  Myocardin-Related Transcription Factors and SRF are required for cytoskeletal dynamics, invasion and experimental metastasis , 2009, Nature Cell Biology.

[2]  W. Gerald,et al.  TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4 , 2008, Cell.

[3]  G. Mills,et al.  Rab25 associates with α5β1 integrin to promote invasive migration in 3D microenvironments , 2007 .

[4]  A. Sharrocks,et al.  Functional interactions between the Forkhead transcription factor FOXK1 and the MADS-box protein SRF , 2007, Nucleic acids research.

[5]  K. Kaibuchi,et al.  Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation , 2007, The Journal of cell biology.

[6]  R. Treisman,et al.  Nuclear Actin Regulates Dynamic Subcellular Localization and Activity of the SRF Cofactor MAL , 2007, Science.

[7]  J. Grosshans,et al.  Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion. , 2007, Genes & development.

[8]  Dan H. Moore,et al.  Increased β1 Integrin Is Associated with Decreased Survival in Invasive Breast Cancer , 2007 .

[9]  Jane Goodall,et al.  Mitf regulation of Dia1 controls melanoma proliferation and invasiveness. , 2006, Genes & development.

[10]  R. Treisman,et al.  MAL and Ternary Complex Factor Use Different Mechanisms To Contact a Common Surface on the Serum Response Factor DNA-Binding Domain , 2006, Molecular and Cellular Biology.

[11]  R. Grosse,et al.  Staying in shape with formins. , 2006, Developmental cell.

[12]  R. Fässler,et al.  β 1 integrin function in vivo: Adhesion, migration and more , 2005, Cancer and Metastasis Reviews.

[13]  E. Olson,et al.  Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin. , 2005, Developmental cell.

[14]  Erik Sahai,et al.  Mechanisms of cancer cell invasion. , 2005, Current opinion in genetics & development.

[15]  John S. Condeelis,et al.  Identification and Testing of a Gene Expression Signature of Invasive Carcinoma Cells within Primary Mammary Tumors , 2004, Cancer Research.

[16]  Bruce M. Spiegelman,et al.  Biological Control through Regulated Transcriptional Coactivators , 2004, Cell.

[17]  W. Muller,et al.  Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. , 2004, Cancer cell.

[18]  P. Rørth,et al.  Evidence for tension-based regulation of Drosophila MAL and SRF during invasive cell migration. , 2004, Developmental cell.

[19]  S. Offermanns,et al.  Plexin‐B family members demonstrate non‐redundant expression patterns in the developing mouse nervous system: an anatomical basis for morphogenetic effects of Sema4D during development , 2004, The European journal of neuroscience.

[20]  K. Wennerberg,et al.  Integrin signaling to the actin cytoskeleton. , 2003, Current opinion in cell biology.

[21]  S. Morris,et al.  Megakaryoblastic Leukemia 1, a Potent Transcriptional Coactivator for Serum Response Factor (SRF), Is Required for Serum Induction of SRF Target Genes , 2003, Molecular and Cellular Biology.

[22]  R. Treisman,et al.  A role for VASP in RhoA‐Diaphanous signalling to actin dynamics and SRF activity , 2003, The EMBO journal.

[23]  R. Treisman,et al.  Actin Dynamics Control SRF Activity by Regulation of Its Coactivator MAL , 2003, Cell.

[24]  A. Colombatti,et al.  β1 Integrin-dependent Cell Adhesion to EMILIN-1 Is Mediated by the gC1q Domain* , 2003, The Journal of Biological Chemistry.

[25]  A I Saeed,et al.  TM4: a free, open-source system for microarray data management and analysis. , 2003, BioTechniques.

[26]  A. Strongin,et al.  Compensation mechanism in tumor cell migration , 2003, The Journal of cell biology.

[27]  R. Treisman,et al.  The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization. , 2002, Molecular biology of the cell.

[28]  Richard O Hynes,et al.  Integrins Bidirectional, Allosteric Signaling Machines , 2002, Cell.

[29]  R. Fässler,et al.  Integrins in invasive growth. , 2002, The Journal of clinical investigation.

[30]  Dean Nizetic,et al.  Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia , 2001, Nature Genetics.

[31]  Nicole Dastugue,et al.  Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[32]  T. Misteli,et al.  High mobility of proteins in the mammalian cell nucleus , 2000, Nature.