Prevention and reversal of hepatic steatosis with a high-protein diet in mice.

[1]  W. Lamers,et al.  Fibroblast growth factor 21 is induced by endoplasmic reticulum stress. , 2013, Biochimie.

[2]  K. Petersen,et al.  Role of Patatin-Like Phospholipase Domain-Containing 3 on Lipid-Induced Hepatic Steatosis and Insulin Resistance in Rats , 2013, Hepatology.

[3]  P. Clifton.  Effects of a high protein diet on body weight and comorbidities associated with obesity , 2012, British Journal of Nutrition.

[4]  E. Akl,et al.  Effects of higher- versus lower-protein diets on health outcomes: a systematic review and meta-analysis , 2012, European Journal of Clinical Nutrition.

[5]  D. Haro,et al.  Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation. , 2012, The Biochemical journal.

[6]  Randal J. Kaufman,et al.  Endoplasmic reticulum stress in liver disease. , 2011, Journal of hepatology.

[7]  D. Jump.  Fatty acid regulation of hepatic lipid metabolism , 2011, Current opinion in clinical nutrition and metabolic care.

[8]  C. Dejong,et al.  Dietary cholesterol, female gender and n-3 fatty acid deficiency are more important factors in the development of non-alcoholic fatty liver disease than the saturation index of the fat , 2011, Nutrition & metabolism.

[9]  E. Kienzle,et al.  Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. , 2011, American journal of physiology. Endocrinology and metabolism.

[10]  K. Xiang,et al.  Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride. , 2010, Journal of hepatology.

[11]  F. Nielsen,et al.  Acid diet (high-meat protein) effects on calcium metabolism and bone health , 2010, Current opinion in clinical nutrition and metabolic care.

[12]  M. Lazar,et al.  Transcriptional Repressor E4-binding Protein 4 (E4BP4) Regulates Metabolic Hormone Fibroblast Growth Factor 21 (FGF21) during Circadian Cycles and Feeding* , 2010, The Journal of Biological Chemistry.

[13]  J. Ijzermans,et al.  Systematic review and meta‐analysis of steatosis as a risk factor in major hepatic resection , 2010, The British journal of surgery.

[14]  F. Nuttall,et al.  Amino acid ingestion and glucose metabolism—A review , 2010, IUBMB life.

[15]  Gregory Stephanopoulos,et al.  Ketogenic Essential Amino Acids Modulate Lipid Synthetic Pathways and Prevent Hepatic Steatosis in Mice , 2010, PloS one.

[16]  J. Flier,et al.  Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State , 2010, Diabetes.

[17]  B. Neuschwander‐Tetri.  Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites , 2010, Hepatology.

[18]  G. Musso,et al.  A meta‐analysis of randomized trials for the treatment of nonalcoholic fatty liver disease , 2010, Hepatology.

[19]  M. Orešič,et al.  Comparison of Lipid and Fatty Acid Composition of the Liver, Subcutaneous and Intra‐abdominal Adipose Tissue, and Serum , 2010, Obesity.

[20]  G. Brinkworth,et al.  Renal function following long-term weight loss in individuals with abdominal obesity on a very-low-carbohydrate diet vs high-carbohydrate diet. , 2010, Journal of the American Dietetic Association.

[21]  Elizabeth M. Brunt,et al.  Pathology of nonalcoholic fatty liver disease , 2010, Nature Reviews Gastroenterology &Hepatology.

[22]  K. Hayashi,et al.  Regulation of hepatic branched-chain alpha-keto acid dehydrogenase kinase in a rat model for type 2 diabetes mellitus at different stages of the disease. , 2010, Biochemical and biophysical research communications.

[23]  B. Spiegelman,et al.  PGC-1α negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erbα axis , 2009, Proceedings of the National Academy of Sciences.

[24]  S. Lanham-New,et al.  Dietary protein and bone health: a systematic review and meta-analysis. , 2009, The American journal of clinical nutrition.

[25]  R. Kreis,et al.  High protein intake reduces intrahepatocellular lipid deposition in humans. , 2009, The American journal of clinical nutrition.

[26]  B. S. Mohammed,et al.  Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity , 2009, Proceedings of the National Academy of Sciences.

[27]  S. Kimball,et al.  eIF2alpha kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver. , 2009, Physiological genomics.

[28]  S. Kliewer,et al.  FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response , 2009, Proceedings of the National Academy of Sciences.

[29]  R. DeFronzo,et al.  Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity. , 2009, American journal of physiology. Endocrinology and metabolism.

[30]  O. Ilkayeva,et al.  Metabolic profiling of PPARα−/− mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[31]  Jason K. Kim,et al.  Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice , 2009, Diabetes.

[32]  M. Katze,et al.  UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. , 2008, Developmental cell.

[33]  D. Ron,et al.  Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice. , 2008, Cell metabolism.

[34]  Ramesh Natarajan,et al.  Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease. , 2008, Gastroenterology.

[35]  Michelle M Wiest,et al.  A lipidomic analysis of nonalcoholic fatty liver disease , 2007, Hepatology.

[36]  S. Burgess,et al.  Diminished Hepatic Gluconeogenesis via Defects in Tricarboxylic Acid Cycle Flux in Peroxisome Proliferator-activated Receptor γ Coactivator-1α (PGC-1α)-deficient Mice* , 2006, Journal of Biological Chemistry.

[37]  R. Brownsey,et al.  Regulation of acetyl-CoA carboxylase. , 2006, Biochemical Society transactions.

[38]  A. Sweatt,et al.  Branched-chain [corrected] amino acid metabolism: implications for establishing safe intakes. , 2005, The Journal of nutrition.

[39]  Robert A. Harris,et al.  Estrogen controls branched-chain amino acid catabolism in female rats. , 2004, The Journal of nutrition.

[40]  J. Huneau,et al.  A long-term high-protein diet markedly reduces adipose tissue without major side effects in Wistar male rats. , 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

[41]  J. Owens,et al.  A high-whey-protein diet reduces body weight gain and alters insulin sensitivity relative to red meat in wistar rats. , 2004, The Journal of nutrition.

[42]  E. Parks.  Dietary carbohydrate's effects on lipogenesis and the relationship of lipogenesis to blood insulin and glucose concentrations , 2002, British Journal of Nutrition.

[43]  H. Troxler,et al.  Hepatic carnitine palmitoyltransferase I deficiency: acylcarnitine profiles in blood spots are highly specific. , 2001, Clinical chemistry.

[44]  N. Ruderman,et al.  Hyperglycemia inhibits insulin activation of Akt/protein kinase B but not phosphatidylinositol 3-kinase in rat skeletal muscle. , 1999, Diabetes.

[45]  J. Saffitz,et al.  A gender-related defect in lipid metabolism and glucose homeostasis in peroxisome proliferator- activated receptor alpha- deficient mice. , 1998, The Journal of clinical investigation.

[46]  R. Harris,et al.  A molecular model of human branched-chain amino acid metabolism. , 1998, The American journal of clinical nutrition.

[47]  J Hirsch,et al.  Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet. , 1996, The Journal of clinical investigation.

[48]  P. G. Reeves,et al.  AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. , 1993, The Journal of nutrition.

[49]  C. Demigné,et al.  Dietary protein paradox: decrease of amino acid availability induced by high-protein diets. , 1993, The American journal of physiology.

[50]  S. Grisolía,et al.  Rats fed prolonged high protein diets show an increase in nitrogen metabolism and liver megamitochondria. , 1987, Archives of biochemistry and biophysics.

[51]  C. Demigné,et al.  Inter-organ relationships between glucose, lactate and amino acids in rats fed on high-carbohydrate or high-protein diets. , 1978, The Biochemical journal.