Influência de aderências peritoneais e fio cirúrgico na tensão de ruptura da parede abdominal em ratos

The recovery of an abdominal procedure depends on many factors, including adhesions. The present study was undertaken to evaluate the influence of four types of suture lines and of adhesions on the tensile strenght of surgical wounds. Sixty Wistar rats were submitted a 5cm laparotomy . The abdomen was closed in two layers with an interrupted suture, using monofilament nylon, polyglicolic acid, plain catgut and chromic catgut . The animals were dividided into three groups: 1- Control; 2- Addition of 0.3 grams of talc into abdominal cavity; 3- Instillation of sodium carboxymethylcellulose (CMC) and talc into abdominal cavity. The animals were assessed on the 7th and 21st postoperative days. The CMC reduced adhesions (p<0,01). The presence of adhesions was able to enhance the tensile strenght. The type of suture line did not influence the tensile strenght.

[1]  A. Petroianu,et al.  Prevention of abdominal adhesions does not interfere with jejunal anastomosis healing. , 1999, International journal of surgical investigation.

[2]  A. Petroianu,et al.  [Effect of methylprednisolone on jejunal anastomotic tension]. , 1994, Arquivos de gastroenterologia.

[3]  Y. Şahin,et al.  Synergistic effects of carboxymethylcellulose and low molecular weight heparin in reducing adhesion formation in the rat uterine horn model , 1994, Acta obstetricia et gynecologica Scandinavica.

[4]  A. Petroianu,et al.  Efeito da metilprednisolona sobre a tensao anastomotica jejunal , 1994 .

[5]  S. Sahlin,et al.  Monofilament versus multifilament absorbable sutures for abdominal closure , 1993, The British journal of surgery.

[6]  Osório Miguel Parra,et al.  DOSE-DEPENDENCIA DA ASSOCIACAO CARBOXIMETILCELULOSE-PAPAINA NA PREVENCAO DE ADERENCIAS PERITONEAIS. ESTUDIO EM RATOS , 1991 .

[7]  T. Gys,et al.  A prospective comparative clinical study between monofilament absorbable and non-absorbable sutures for abdominal wall closure. , 1989, Acta chirurgica Belgica.

[8]  R. Edlich,et al.  The effect of new monofilament absorbable sutures on the healing of musculoaponeurotic incisions, gastrotomies, and colonic anastomoses. , 1989, Archives of surgery.

[9]  A. Petroianu.  Synthesis of surgical wounds without skin suture. , 1988, Plastic and reconstructive surgery.

[10]  G. Mcentee,et al.  Current spectrum of intestinal obstruction , 1987, The British journal of surgery.

[11]  T. van Vroonhoven,et al.  Fascia closure after midline laparotomy: Results of a randomized trial , 1987, The British journal of surgery.

[12]  G. V. Poole.  Mechanical factors in abdominal wound closure: the prevention of fascial dehiscence. , 1985, Surgery.

[13]  Aldrete Js,et al.  Abdominal wound closure. , 1984 .

[14]  C. Balch,et al.  Abdominal wound closure. A randomized prospective study of 571 patients comparing continuous vs. interrupted suture techniques. , 1983, Annals of surgery.

[15]  H. Ellis.  The causes and prevention of intestinal adhesions , 1982, The British journal of surgery.

[16]  Bucknall Te.  Abdominal wound closure: choice of suture , 1981 .

[17]  H. Ellis,et al.  Abdominal wound closure--a comparison of monofilament nylon and polyglycolic acid. , 1981, Surgery.

[18]  R. Brentani,et al.  Differential staining of collagens type I, II and III by Sirius Red and polarization microscopy. , 1978, Archivum histologicum Japonicum = Nihon soshikigaku kiroku.

[19]  D. Willigan,et al.  Human tissue reaction to sutures. , 1975 .

[20]  M. Weibel,et al.  Peritoneal adhesions and their relation to abdominal surgery. A postmortem study. , 1973, American journal of surgery.

[21]  V. S. Constantine,et al.  Selective staining of human dermal collagen. II. The use of picrosirius red F3BA with polarization microscopy. , 1968, Journal of Investigative Dermatology.

[22]  H. Ellis,et al.  The aetiology of post‐operative abdominal adhesions an experimental study , 1962, The British journal of surgery.

[23]  Smith Jw,et al.  The prevention and treatment of intestinal adhesions. , 1960 .

[24]  J. D. Feldman,et al.  Effect of streptokinase-streptodornase on peritoneal talc adhesions and granulomas; experimental study. , 1954, A.M.A. archives of surgery.