Breast arterial calcification and hypertension associated with vertebral fracture

Aim:  Arterial calcification and osteoporosis commonly accompany one another in postmenopausal women. Hypertension is a known contributing factor to arterial calcification. Thus, we aimed to investigate any associations between hypertension, arterial calcification and vertebral fractures in a cross‐sectional study in Japanese postmenopausal women.

[1]  A. Hofman,et al.  Bone mineral density and the risk of breast cancer: the Rotterdam Study. , 2003, Bone.

[2]  J. Manson,et al.  Estrogen therapy and coronary-artery calcification. , 2007, The New England journal of medicine.

[3]  H K Genant,et al.  Vertebral fractures and mortality in older women: a prospective study. Study of Osteoporotic Fractures Research Group. , 1999, Archives of internal medicine.

[4]  Charles Kooperberg,et al.  Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. , 2002, JAMA.

[5]  S. Cummings,et al.  Risk factors for breast cancer in older women: the relative contribution of bone mineral density and other established risk factors , 2007, Breast Cancer Research and Treatment.

[6]  J A Kanis,et al.  Epidemiology of vertebral osteoporosis. , 1992, Bone.

[7]  F. Cappuccio,et al.  Unravelling the links between calcium excretion, salt intake, hypertension, kidney stones and bone metabolism. , 2000, Journal of nephrology.

[8]  Y. van der Graaf,et al.  Breast arterial calcifications: association with diabetes mellitus and cardiovascular mortality. Work in progress. , 1996, Radiology.

[9]  S. Cummings,et al.  Relationship Between Osteoporosis and Cardiovascular Disease in Postmenopausal Women , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[10]  Shiro Tanaka,et al.  Contributions of 25-hydroxyvitamin D, co-morbidities and bone mass to mortality in Japanese postmenopausal women. , 2009, Bone.

[11]  Hajime Orimo,et al.  Diagnostic criteria for primary osteoporosis: year 2000 revision , 2001, Journal of Bone and Mineral Metabolism.

[12]  R. Khalil,et al.  Estrogenic compounds, estrogen receptors and vascular cell signaling in the aging blood vessels. , 2009, Current medicinal chemistry.

[13]  M. Fukunaga,et al.  Fracture Prediction From Bone Mineral Density in Japanese Men and Women , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[14]  M. Iki,et al.  Low bone mass is associated with carotid atherosclerosis in postmenopausal women: The Japanese Population-based Osteoporosis (JPOS) Cohort Study , 2008, Osteoporosis International.

[15]  A. Hofman,et al.  Bone Mineral Density and the Risk of Peripheral Arterial Disease: The Rotterdam Study , 2002, Calcified Tissue International.

[16]  M. Kurabayashi,et al.  Relationship between Carotid Atherosclerosis and Lumbar Spine Bone Mineral Density in Postmenopausal Women , 2008, Hypertension Research.

[17]  W. Shen,et al.  The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: results from the Multiple Outcomes of Raloxifene Evaluation Study. , 2001, Arthritis and rheumatism.

[18]  J. Woo,et al.  Dietary intake, blood pressure and osteoporosis , 2009, Journal of Human Hypertension.

[19]  Y. van der Graaf,et al.  Mammograms may convey more than breast cancer risk: breast arterial calcification and arterio-sclerotic related diseases in women of the DOM cohort. , 1996, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[20]  E. Kang,et al.  Echogenic Carotid Artery Plaques are Associated with Vertebral Fractures in Postmenopausal Women with Low Bone Mass , 2008, Calcified Tissue International.

[21]  C. Cooper,et al.  Health‐Related Quality of Life in Postmenopausal Women With Low BMD With or Without Prevalent Vertebral Fractures , 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[22]  L. Mosca,et al.  Reduced bone mineral density is associated with breast arterial calcification. , 2008, The Journal of clinical endocrinology and metabolism.

[23]  F. Vescini,et al.  Salt intake, hypertension, and osteoporosis. , 2009, Journal of endocrinological investigation.

[24]  S. Cummings,et al.  Comparison of semiquantitative visual and quantitative morphometric assessment of prevalent and incident vertebral fractures in osteoporosis , 1996 .

[25]  M. Aickin,et al.  The DASH diet and sodium reduction improve markers of bone turnover and calcium metabolism in adults. , 2003, The Journal of nutrition.

[26]  P. Vestergaard,et al.  Hypertension Is a Risk Factor for Fractures , 2009, Calcified Tissue International.

[27]  W. Howard.  High Attributable Risk of Elevated C-Reactive Protein Level to Conventional Coronary Heart Disease Risk Factors: The Third National Health and Nutrition Examination SurveyMiller M, Zhan M, Havas S (Univ of Maryland, Baltimore) Arch Intern Med 165:2063–2068, 2005§ , 2006 .

[28]  W. Edwards,et al.  Estrogen status correlates with the calcium content of coronary atherosclerotic plaques in women. , 2002, The Journal of clinical endocrinology and metabolism.

[29]  R. Mangiafico,et al.  Increased prevalence of peripheral arterial disease in osteoporotic postmenopausal women , 2006, Journal of Bone and Mineral Metabolism.