Electrical Design-for-Manufacturability (DFM) checks are developed to quantify layout enhancements and their impact on circuit performance for analog designs. A database containing circuit topologies of analog matched devices is built. Then, connectivity checks scan the schematics for topologies from the database. If a matching topology were detected, the matched devices are mapped to layout for layout matching checks. If layout mismatches are detected, electrical DFM checks are used to quantify the imbalance in terms of parasitic resistance and capacitance. The electrical DFM checks are applied to quantify the impact due to routing, fill, and DFM fixing on three, 22nm analog design blocks. Fill insertion’s contribution to RC change is the greatest followed by routing and DFM fixing, with a maximum change of 7%, 5%, and less than 1%, respectively. Symmetry-aware layout insertions preserve the matching of electrical parameters, showing zero mismatch. All designs pass electrical DFM checks as results are within the expected design tolerances.