Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain
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C. Troakes | W. Noble | Christopher C. J. Miller | N. Hartopp | P. Gomez-Suaga | S. Paillusson | Dawn H W Lau | G. M. Mórotz | J. Greig | H. Rupawala | Dawn H. W. Lau | Sebastien Paillusson | Gábor M Mórotz | Sébastien Paillusson
[1] P. Nelson,et al. The Mitochondria-Associated ER Membranes Are Novel Subcellular Locations Enriched for Inflammatory-Responsive MicroRNAs , 2020, Molecular Neurobiology.
[2] W. Noble,et al. Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer’s disease and regulates axonal transport and processing of the amyloid precursor protein , 2019, Acta Neuropathologica Communications.
[3] T. Wisniewski,et al. Perturbed mitochondria–ER contacts in live neurons that model the amyloid pathology of Alzheimer's disease , 2019, Journal of Cell Science.
[4] A. Konnerth,et al. Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity , 2019, Nature Neuroscience.
[5] M. Brini,et al. splitGFP Technology Reveals Dose-Dependent ER-Mitochondria Interface Modulation by α-Synuclein A53T and A30P Mutants , 2019, Cells.
[6] A. Zorzano,et al. Metabolic implications of organelle–mitochondria communication , 2019, EMBO reports.
[7] K. Mikoshiba,et al. IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer , 2019, Nature Communications.
[8] Z. Sheng,et al. Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts , 2019, Nature Communications.
[9] Teruo Hayashi. The Sigma-1 Receptor in Cellular Stress Signaling , 2019, Front. Neurosci..
[10] Eleanor D. Robinson,et al. LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer’s disease brains , 2019, Acta Neuropathologica Communications.
[11] W. Noble,et al. The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity , 2019, Acta neuropathologica communications.
[12] M. Hiltunen,et al. Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients , 2018, Acta Neuropathologica Communications.
[13] J. Lippincott-Schwartz,et al. Interacting organelles. , 2018, Current opinion in cell biology.
[14] G. Hajnóczky,et al. Endoplasmic Reticulum-Mitochondrial Contactology: Structure and Signaling Functions. , 2018, Trends in cell biology.
[15] Christopher C. J. Miller,et al. Disruption of ER−mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis , 2018, Cell Death & Disease.
[16] E. Schon,et al. A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease , 2018, Cell Death & Disease.
[17] Yusuke Hirabayashi,et al. ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons , 2017, Science.
[18] E. Schon,et al. Increased localization of APP‐C99 in mitochondria‐associated ER membranes causes mitochondrial dysfunction in Alzheimer disease , 2017, The EMBO journal.
[19] B. Winblad,et al. APP mouse models for Alzheimer's disease preclinical studies , 2017, The EMBO journal.
[20] J. Rieusset. Mitochondria-associated membranes (MAMs): An emerging platform connecting energy and immune sensing to metabolic flexibility. , 2017, Biochemical and biophysical research communications.
[21] Michael J. Devine,et al. α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production , 2017, Acta Neuropathologica.
[22] W. Noble,et al. The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy , 2017, Current Biology.
[23] F. Checler,et al. Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes , 2016, Journal of Alzheimer's disease : JAD.
[24] H. Kiyama,et al. Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1‐ and SOD1‐linked ALS , 2016, EMBO molecular medicine.
[25] S. Pulst,et al. Cellular and circuit mechanisms underlying spinocerebellar ataxias , 2016, The Journal of physiology.
[26] T. Hortobágyi,et al. Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss , 2016, Brain : a journal of neurology.
[27] C. Shaw,et al. ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations , 2016, EMBO reports.
[28] W. Noble,et al. Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease , 2016, Acta neuropathologica communications.
[29] Shang-Yi Tsai,et al. The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems. , 2016, Trends in pharmacological sciences.
[30] Matthew A. Wade,et al. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain , 2016, Acta Neuropathologica Communications.
[31] Christopher C. J. Miller,et al. There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases , 2016, Trends in Neurosciences.
[32] Colleen J. Thomas,et al. The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in Neurodegeneration , 2016, Front. Cell Dev. Biol..
[33] B. Asselbergh,et al. Mitochondria-associated membranes as hubs for neurodegeneration , 2016, Acta Neuropathologica.
[34] E. Schon,et al. ApoE4 upregulates the activity of mitochondria‐associated ER membranes , 2015, EMBO reports.
[35] A. Palmeri,et al. Rodent models for Alzheimer’s disease drug discovery , 2015, Expert opinion on drug discovery.
[36] R. Chrast,et al. Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration. , 2015, Brain : a journal of neurology.
[37] T. Hortobágyi,et al. Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer’s disease , 2015, Molecular Brain.
[38] M. Ankarcrona,et al. Amyloid-β peptides are generated in mitochondria-associated endoplasmic reticulum membranes. , 2014, Journal of Alzheimer's disease : JAD.
[39] L. Petrucelli,et al. ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43 , 2014, Nature Communications.
[40] I. Ferrer,et al. Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis. , 2014, The Journal of clinical investigation.
[41] B. Winblad,et al. Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer’s disease and related models , 2013, Proceedings of the National Academy of Sciences.
[42] C. Troakes,et al. Prostate-derived Sterile 20-like Kinases (PSKs/TAOKs) Phosphorylate Tau Protein and Are Activated in Tangle-bearing Neurons in Alzheimer Disease* , 2013, The Journal of Biological Chemistry.
[43] G. Voeltz,et al. Endoplasmic reticulum–mitochondria contacts: function of the junction , 2012, Nature Reviews Molecular Cell Biology.
[44] E. Schon,et al. Upregulated function of mitochondria-associated ER membranes in Alzheimer disease , 2012, The EMBO journal.
[45] J. Foskett,et al. Mitochondrial Ca(2+) signals in autophagy. , 2012, Cell calcium.
[46] G. Schellenberg,et al. The genetics and neuropathology of Alzheimer’s disease , 2012, Acta Neuropathologica.
[47] Bente Pakkenberg,et al. Stereological quantification of the cerebellum in patients with Alzheimer's disease , 2012, Neurobiology of Aging.
[48] Kristopher L. Nazor,et al. Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells , 2012, Nature.
[49] C. Shaw,et al. VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis , 2011, Human molecular genetics.
[50] M. Bortolozzi,et al. Presenilin 2 modulates endoplasmic reticulum (ER)–mitochondria interactions and Ca2+ cross-talk , 2011, Proceedings of the National Academy of Sciences.
[51] E. Schon,et al. Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. , 2009, The American journal of pathology.
[52] P. Pinton,et al. Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells , 2009, Nature Protocols.
[53] Simon Lovestone,et al. The GSK3 hypothesis of Alzheimer's disease , 2008, Journal of neurochemistry.
[54] K. Leroy,et al. Increased level of active GSK‐3β in Alzheimer’s disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration , 2007, Neuropathology and applied neurobiology.
[55] U. Landegren,et al. Direct observation of individual endogenous protein complexes in situ by proximity ligation , 2006, Nature Methods.
[56] Anthony Holland,et al. Increased MAP kinase activity in Alzheimer's and Down syndrome but not in schizophrenia human brain , 2004, The European journal of neuroscience.
[57] I. Ferrer,et al. Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration , 2002, Acta Neuropathologica.
[58] S. Snyder,et al. Differential cellular expression of isoforms of inositol 1,4,5‐triphosphate receptors in neurons and glia in brain , 1999, The Journal of comparative neurology.
[59] D. Mann,et al. Pyramidal nerve cell loss in Alzheimer's disease. , 1996, Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration.
[60] Simon Lovestone,et al. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells , 1994, Current Biology.
[61] M. Bootman,et al. Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction. , 1994, The Journal of biological chemistry.