Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice.
暂无分享,去创建一个
T. Spires-Jones | M. Garcia-Alloza | B. Bacskai | E. Berrocoso | Mar Pacheco-Herrero | J. J. Ramos-Rodríguez | D. Thyssen | M. Murillo-Carretero
[1] C. Ayata,et al. Cerebrovascular lesions induce transient β-amyloid deposition. , 2011, Brain : a journal of neurology.
[2] J. Wuu,et al. Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease. , 2011, The American journal of pathology.
[3] M. Jucker,et al. Pathogenic protein seeding in alzheimer disease and other neurodegenerative disorders , 2011, Annals of neurology.
[4] S. DeKosky,et al. Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease , 2011, Neurology.
[5] Onofre Combarros,et al. Detection of early Alzheimer's disease in MCI patients by the combination of MMSE and an episodic memory test , 2011, BMC neurology.
[6] M. Sabbagh,et al. Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer’s disease , 2011, Acta Neuropathologica.
[7] Ying-Dong Zhang,et al. Anti-TNF-α reduces amyloid plaques and tau phosphorylation and induces CD11c-positive dendritic-like cell in the APP/PS1 transgenic mouse brains , 2011, Brain Research.
[8] B. Hyman,et al. Antioxidants have a rapid and long-lasting effect on neuritic abnormalities in APP:PS1 mice , 2010, Neurobiology of Aging.
[9] Julie A. Harris,et al. Transsynaptic Progression of Amyloid-β-Induced Neuronal Dysfunction within the Entorhinal-Hippocampal Network , 2010, Neuron.
[10] E. Capetillo-Zarate,et al. Effects of Synaptic Modulation on β-Amyloid, Synaptophysin, and Memory Performance in Alzheimer's Disease Transgenic Mice , 2010, The Journal of Neuroscience.
[11] R. Bernabeu,et al. The p75 neurotrophin receptor is expressed by adult mouse dentate progenitor cells and regulates neuronal and non-neuronal cell genesis , 2010, BMC Neuroscience.
[12] Qiao-Xin Li,et al. Aβ1–42 stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor , 2009, Neurobiology of Aging.
[13] A. Aguzzi,et al. Induction of cerebral β-amyloidosis: Intracerebral versus systemic Aβ inoculation , 2009, Proceedings of the National Academy of Sciences.
[14] M. Baxter,et al. Efficacy of a murine-p75-saporin immunotoxin for selective lesions of basal forebrain cholinergic neurons in mice , 2009, Neuroscience Letters.
[15] B. Cosquer,et al. Neuroanatomical and behavioral effects of a novel version of the cholinergic immunotoxin mu p75‐saporin in mice , 2008, Hippocampus.
[16] Guojun Bu,et al. Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo , 2008, Neuron.
[17] D. Holtzman,et al. Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease , 2008, Nature.
[18] S. DeKosky,et al. Cholinergic forebrain degeneration in the APPswe/PS1ΔE9 transgenic mouse , 2007, Neurobiology of Disease.
[19] B. Hyman,et al. Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model , 2007, Journal of neurochemistry.
[20] Brian J. Bacskai,et al. Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease , 2006, Neurobiology of Disease.
[21] M. Garcia-Alloza,et al. Effect of Selective Cholinergic Denervation on the Serotonergic System: Implications for Learning and Memory , 2006, Journal of neuropathology and experimental neurology.
[22] Joseph P. Huston,et al. Integrated memory for objects, places, and temporal order: Evidence for episodic-like memory in mice , 2005, Neurobiology of Learning and Memory.
[23] D. Borchelt,et al. Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease , 2005, The Journal of Neuroscience.
[24] D. Holtzman,et al. Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice. , 2005, The Journal of clinical investigation.
[25] Dominic M. Walsh,et al. Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease , 2004, Neuron.
[26] A. Granholm,et al. Minocycline protects basal forebrain cholinergic neurons from mu p75‐saporin immunotoxic lesioning , 2004, The European journal of neuroscience.
[27] A. Škoch,et al. Classification of calf muscle MR images by texture analysis , 2004, Magnetic Resonance Materials in Physics, Biology and Medicine.
[28] Joanna L. Jankowsky,et al. Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase , 2004 .
[29] D. German,et al. Cholinergic neuropathology in a mouse model of Alzheimer's disease , 2003, The Journal of comparative neurology.
[30] Bettina Schmitt,et al. Selection of D‐Amino‐Acid Peptides That Bind to Alzheimer's Disease Amyloid Peptide Aβ1–42 by Mirror Image Phage Display , 2003, Chembiochem : a European journal of chemical biology.
[31] K. Henke,et al. Antibodies against β-Amyloid Slow Cognitive Decline in Alzheimer's Disease , 2003, Neuron.
[32] D. Price,et al. Disruption of Corticocortical Connections Ameliorates Amyloid Burden in Terminal Fields in a Transgenic Model of Aβ Amyloidosis , 2002, The Journal of Neuroscience.
[33] D. Peterson,et al. Evidence That Synaptically Released β-Amyloid Accumulates as Extracellular Deposits in the Hippocampus of Transgenic Mice , 2002, The Journal of Neuroscience.
[34] H. Tanila,et al. Fimbria–Fornix Lesion Does Not Affect APP Levels and Amyloid Deposition in the Hippocampus of APP+PS1 Double Transgenic Mice , 2002, Experimental Neurology.
[35] B. Hyman,et al. Imaging Aβ Plaques in Living Transgenic Mice with Multiphoton Microscopy and Methoxy‐X04, a Systemically Administered Congo Red Derivative , 2002, Journal of neuropathology and experimental neurology.
[36] M. Baxter,et al. Selective Immunolesions of Cholinergic Neurons in Mice: Effects on Neuroanatomy, Neurochemistry, and Behavior , 2001, The Journal of Neuroscience.
[37] B T Hyman,et al. Growth Arrest of Individual Senile Plaques in a Model of Alzheimer's Disease Observed by In Vivo Multiphoton Microscopy , 2001, The Journal of Neuroscience.
[38] J. Growdon,et al. The selective muscarinic M1 agonist AF102B decreases levels of total Aβ in cerebrospinal fluid of patients with Alzheimer's disease , 2000, Annals of neurology.
[39] W. Honer,et al. Cortical Cholinergic Denervation Elicits Vascular Aβ Deposition , 2000 .
[40] G. Hu,et al. Comparison of the effects of cholinesterase inhibitors on [3H]MK-801 binding in rat cerebral cortex , 1999, Neuroscience Letters.
[41] Steffen Roßner,et al. The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling , 1998, Progress in Neurobiology.
[42] G. Leanza. Chronic elevation of amyloid precursor protein expression in the neocortex and hippocampus of rats with selective cholinergic lesions , 1998, Neuroscience Letters.
[43] T. Deacon,et al. Chronic cognitive deficits and amyloid precursor protein elevation after selective immunotoxin lesions of the basal forebrain cholinergic system , 1998, Neuroreport.
[44] L. Harrell,et al. Cholinergic activity and amyloid precursor protein metabolism , 1997, Brain Research Reviews.
[45] Richard Hollister,et al. Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease , 1997, Annals of neurology.
[46] S. Heckers,et al. Differential effects on spatial navigation of immunotoxin-induced cholinergic lesions of the medial septal area and nucleus basalis magnocellularis , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[47] R. Wurtman. Choline metabolism as a basis for the selective vulnerability of cholinergic neurons , 1992, Trends in Neurosciences.
[48] B. Chozick. The nucleus basalis of Meynert in neurological dementing disease: a review. , 1987, The International journal of neuroscience.
[49] R. Morris. Developments of a water-maze procedure for studying spatial learning in the rat , 1984, Journal of Neuroscience Methods.
[50] Peter Desain,et al. Society for Neuroscience Meeting , 2010 .
[51] S. DeKosky,et al. Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse. , 2007, Neurobiology of disease.
[52] Mathias Hoehn,et al. Locus Ceruleus Degeneration Promotes Alzheimer Pathogenesis in Amyloid Precursor Protein 23 Transgenic Mice , 2006, The Journal of Neuroscience.
[53] D. Borchelt,et al. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. , 2004, Human molecular genetics.
[54] K. Henke,et al. Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease. , 2003, Neuron.
[55] W. Honer,et al. Cortical cholinergic denervation elicits vascular A beta deposition. , 2000, Annals of the New York Academy of Sciences.