A vitamin D C/D ring-derived compound with cytotoxicity
暂无分享,去创建一个
M. Otsuka | M. Fujita | Halil I. Ciftci | Mohamed O. Radwan | Hiroshi Tateishi | T. Toma | Tanima Biswas | A. Hassan | Y. Tahara
[1] M. Can,et al. EGFR-Targeted Pentacyclic Triterpene Analogues for Glioma Therapy , 2021, International journal of molecular sciences.
[2] P. Mayer,et al. Synthesis of Seco ‐Analogues of the DHCR24 Inhibitor SH‐42 , 2020 .
[3] K. Chiba. Discovery of fingolimod based on the chemical modification of a natural product from the fungus, Isaria sinclairii , 2020, The Journal of Antibiotics.
[4] Wei Wang,et al. Vitamin D regulates cell viability, migration and proliferation by suppressing galectin-3 (Gal-3) gene in ovarian cancer cells , 2020, Journal of Biosciences.
[5] Stephen L. Abrams,et al. Targeting GSK3 and Associated Signaling Pathways Involved in Cancer , 2020, Cells.
[6] K. Yasuda,et al. Synthesis and CYP24A1-Dependent Metabolism of 23-Fluorinated Vitamin D3 Analogues , 2019, ACS omega.
[7] C. Carlberg,et al. Vitamin D and Its Synthetic Analogs , 2019, Journal of medicinal chemistry.
[8] Jiachen Wen,et al. Structure–Activity Relationship Studies of Vitamin D3 Analogues Containing an Ether or Thioether Linker as Hedgehog Pathway Inhibitors , 2018, ChemMedChem.
[9] M. Can,et al. The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities. , 2018, Biological & pharmaceutical bulletin.
[10] Sang-Min Jeon,et al. Exploring vitamin D metabolism and function in cancer , 2018, Experimental & Molecular Medicine.
[11] P. Dhawan,et al. Vitamin D, calcium homeostasis and aging , 2016, Bone Research.
[12] M. Uesugi,et al. Synthesis of Diastereomers of 1,3-cis-25-Dihydroxy-19-norvitamin D3. , 2016, Chemical & pharmaceutical bulletin.
[13] M. Uesugi,et al. Synthesis of 24,24-Difluoro-1,3-cis-25-dihydroxy-19-norvitamin D3 Derivatives and Evaluation of Their Vitamin D Receptor-Binding Affinity. , 2016, Biological & pharmaceutical bulletin.
[14] R. Peterson,et al. A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed. , 2015, Cell reports.
[15] Daniel S Raccuia,et al. Vitamin D3 analogues that contain modified A- and seco-B-rings as hedgehog pathway inhibitors. , 2015, European journal of medicinal chemistry.
[16] C. Shao,et al. Subergorgiaols A–L, 9,10-secosteroids from the South China Sea gorgonian Subergorgia rubra , 2015, Steroids.
[17] Ferdinand Molnár,et al. Structural considerations of vitamin D signaling , 2014, Front. Physiol..
[18] E. Giovannucci,et al. The role of vitamin D in reducing cancer risk and progression , 2014, Nature Reviews Cancer.
[19] D. Bikle,et al. Vitamin D metabolism, mechanism of action, and clinical applications. , 2014, Chemistry & biology.
[20] Steven M. Lemieux,et al. Analogues of the Inhoffen-Lythgoe diol with anti-proliferative activity. , 2013, Bioorganic & medicinal chemistry letters.
[21] Steven M. Lemieux,et al. Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway. , 2012, Bioorganic & medicinal chemistry letters.
[22] K. Adachi,et al. Discovery of fingolimod, the sphingosine 1-phosphate receptor modulator and its application for the therapy of multiple sclerosis. , 2012, Future medicinal chemistry.
[23] H. DeLuca,et al. Methyl substitution of the 25-hydroxy group on 2-methylene-19-nor-1alpha,25-dihydroxyvitamin D3 (2MD) reduces potency but allows bone selectivity. , 2007, Archives of biochemistry and biophysics.
[24] T. Duka,et al. Highly Potent and Specific GSK‐3β Inhibitors That Block Tau Phosphorylation and Decrease α‐Synuclein Protein Expression in a Cellular Model of Parkinson's Disease , 2006, ChemMedChem.
[25] H. DeLuca. Overview of general physiologic features and functions of vitamin D. , 2004, The American journal of clinical nutrition.
[26] H. DeLuca,et al. Novel synthesis of 19-nor-vitamin d compounds , 1991 .
[27] T. Oppé,et al. Vitamin D deficiency. , 1979, British medical journal.
[28] D. Green,et al. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD‐specific caspase activation and independently of mitochondrial transmembrane depolarization , 1998, The EMBO journal.