Medicinal and aromatic plant analysis in high-throughput - technology, possibilities and applications of the numares NMR-platform.

To ensure an efficient analysis of medicinal and aromatic plants and to be able to handle the high variability occurring in matrices and sample types a variety of complementary analytical methods is required. The numares AG provides a new and innovative approach based on nuclear magnetic resonance (NMR) spectroscopy to assist plant breeders and industry in the analysis and optimization of breeding projects, process flows and in quality control. The technology, its potential and applications are presented below based on selected examples.

[1]  H. Stuppner,et al.  1H NMR-based metabolic profiling and target analysis: a combined approach for the quality control of Thymus vulgaris , 2011, Metabolomics.

[2]  Manfred Spraul,et al.  Targeted and nontargeted wine analysis by (1)h NMR spectroscopy combined with multivariate statistical analysis. Differentiation of important parameters: grape variety, geographical origin, year of vintage. , 2013, Journal of agricultural and food chemistry.

[3]  Y. Choi,et al.  Quality control of herbal material and phytopharmaceuticals with MS and NMR based metabolic fingerprinting. , 2009, Planta medica.

[4]  J. A. Teixeira da Silva,et al.  NMR metabolomics of berry quality in sea buckthorn (Hippophae L.) , 2012, Molecular Breeding.

[5]  David S. Wishart,et al.  Characterization of biopharmaceuticals by NMR spectroscopy , 2013 .

[6]  Manfred Spraul,et al.  NMR-Spectroscopy for Nontargeted Screening and Simultaneous Quantification of Health-Relevant Compounds in Foods: The Example of Melamine , 2009, Journal of agricultural and food chemistry.

[7]  C. Simmler,et al.  Universal quantitative NMR analysis of complex natural samples. , 2014, Current opinion in biotechnology.

[8]  Emmanuel Hatzakis,et al.  Quality assessment and authentication of virgin olive oil by NMR spectroscopy: a critical review. , 2013, Analytica chimica acta.

[9]  H. Stuppner,et al.  Identification and quantification of major steviol glycosides in Stevia rebaudiana purified extracts by 1H NMR spectroscopy. , 2011, Journal of agricultural and food chemistry.

[10]  Henry H. N. Lam,et al.  Quality Control of Danggui Buxue Tang, a Traditional Chinese Medicine Decoction, by 1H-NMR Metabolic Profiling , 2014, Evidence-based complementary and alternative medicine : eCAM.

[11]  M. Spraul,et al.  NMR-Based Mixture Analysis on the Example of Fruit Juice Quality Control Using Statistics and Quantification , 2008 .

[12]  C. Napoli,et al.  NMR screening in the quality control of food and nutraceuticals , 2014 .