Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function

[1]  R. Spurney,et al.  Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1) , 2018, Scientific Reports.

[2]  R. Chai,et al.  Meclofenamic Acid Reduces Reactive Oxygen Species Accumulation and Apoptosis, Inhibits Excessive Autophagy, and Protects Hair Cell-Like HEI-OC1 Cells From Cisplatin-Induced Damage , 2018, Front. Cell. Neurosci..

[3]  Shan Sun,et al.  Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea , 2018, Front. Mol. Neurosci..

[4]  R. Chai,et al.  Role of Autophagy in Auditory System Development and Survival , 2018 .

[5]  R. Chai,et al.  Wnt Signaling Activates TP53-Induced Glycolysis and Apoptosis Regulator and Protects Against Cisplatin-Induced Spiral Ganglion Neuron Damage in the Mouse Cochlea. , 2018, Antioxidants & redox signaling.

[6]  Dong Liu,et al.  A Three-Dimensional Culture System with Matrigel Promotes Purified Spiral Ganglion Neuron Survival and Function In Vitro , 2018, Molecular Neurobiology.

[7]  Shan Sun,et al.  Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2 , 2018, Drug delivery.

[8]  Shan Sun,et al.  Hedgehog Signaling Promotes the Proliferation and Subsequent Hair Cell Formation of Progenitor Cells in the Neonatal Mouse Cochlea , 2017, Front. Mol. Neurosci..

[9]  J. Li,et al.  Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice , 2017, Front. Mol. Neurosci..

[10]  Yingying Liu,et al.  The shaker-1 mouse myosin VIIa deafness mutation results in a severely reduced rate of the ATP hydrolysis step , 2017, The Journal of Biological Chemistry.

[11]  K. Rottner,et al.  Actin assembly mechanisms at a glance , 2017, Journal of Cell Science.

[12]  Dong Liu,et al.  Autophagy protects auditory hair cells against neomycin-induced damage , 2017, Autophagy.

[13]  Zhengping Jia,et al.  Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain , 2017, Neuropharmacology.

[14]  R. Fettiplace Hair Cell Transduction, Tuning, and Synaptic Transmission in the Mammalian Cochlea. , 2017, Comprehensive Physiology.

[15]  R. Chai,et al.  Auditory Neuropathy after Damage to Cochlear Spiral Ganglion Neurons in Mice Resulting from Conditional Expression of Diphtheria Toxin Receptors , 2017, Scientific Reports.

[16]  Fuping Qian,et al.  Insm1a Regulates Motor Neuron Development in Zebrafish , 2017, bioRxiv.

[17]  T. Reichenbach,et al.  Hair bundles of cochlear outer hair cells are shaped to minimize their fluid-dynamic resistance , 2017, Scientific Reports.

[18]  A. Tsaturyan,et al.  Cooperativity of myosin interaction with thin filaments is enhanced by stabilizing substitutions in tropomyosin , 2017, Journal of Muscle Research and Cell Motility.

[19]  Stephen T. Paquette,et al.  Severe hearing loss and outer hair cell death in homozygous Foxo3 knockout mice after moderate noise exposure , 2017, Scientific Reports.

[20]  Shanting Zhao,et al.  Aberrant expression of LIMK1 impairs neuronal migration during neocortex development , 2016, Histochemistry and Cell Biology.

[21]  Ruhui Lin,et al.  Electroacupuncture Regulates Hippocampal Synaptic Plasticity via miR-134-Mediated LIMK1 Function in Rats with Ischemic Stroke , 2017, Neural plasticity.

[22]  M. Rust ADF/cofilin: a crucial regulator of synapse physiology and behavior , 2015, Cellular and Molecular Life Sciences.

[23]  Channy Park,et al.  PKCα-Mediated Signals Regulate the Motile Responses of Cochlear Outer Hair Cells. , 2015, Biophysical journal.

[24]  K. Ohashi Roles of cofilin in development and its mechanisms of regulation , 2015, Development, growth & differentiation.

[25]  U. Pirvola,et al.  The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea , 2015, Biology Open.

[26]  O. Snead,et al.  LIMK1 Regulates Long-Term Memory and Synaptic Plasticity via the Transcriptional Factor CREB , 2015, Molecular and Cellular Biology.

[27]  Lijuan Shi,et al.  Ribbon Synapse Plasticity in the Cochleae of Guinea Pigs after Noise-Induced Silent Damage , 2013, PloS one.

[28]  A. Edge,et al.  Regenerated Synapses Between Postnatal Hair Cells and Auditory Neurons , 2013, Journal of the Association for Research in Otolaryngology.

[29]  K. Mizuno Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation. , 2013, Cellular signalling.

[30]  Gong Chen,et al.  Cofilin Aggregation Blocks Intracellular Trafficking and Induces Synaptic Loss in Hippocampal Neurons* , 2011, The Journal of Biological Chemistry.

[31]  B. McEwen,et al.  LIM kinase mediates estrogen action on the actin depolymerization factor Cofilin , 2011, Brain Research.

[32]  L. F. Franchini,et al.  Prestin and the cholinergic receptor of hair cells: Positively-selected proteins in mammals , 2011, Hearing Research.

[33]  J. L. Rosa,et al.  The p38/MK2/Hsp25 Pathway Is Required for BMP-2-Induced Cell Migration , 2011, PloS one.

[34]  N. Matsumoto,et al.  Pivotal role of actin depolymerization in the regulation of cochlear outer hair cell motility. , 2010, Biophysical journal.

[35]  Ulrich Müller,et al.  The cell biology of hearing , 2010, The Journal of cell biology.

[36]  B. Kachar,et al.  Changes in plasma membrane structure and electromotile properties in prestin deficient outer hair cells , 2009, Cytoskeleton.

[37]  C. Petit,et al.  LINKING DEAFNESS GENES TO HAIR-BUNDLE DEVELOPMENT AND FUNCTION , 2009, Nature Neuroscience.

[38]  J. Hugnot,et al.  Cochlear stem/progenitor cells from a postnatal cochlea respond to Jagged1 and demonstrate that notch signaling promotes sphere formation and sensory potential , 2008, Mechanisms of Development.

[39]  D. Ryugo Projections of low spontaneous rate, high threshold auditory nerve fibers to the small cell cap of the cochlear nucleus in cats , 2008, Neuroscience.

[40]  Alan D. Baddeley,et al.  Long-Term Memory for Verbal and Visual Information in Down Syndrome and Williams Syndrome: Performance on the Doors and People Test , 2007, Cortex.

[41]  C. Hoogenraad,et al.  The postsynaptic architecture of excitatory synapses: a more quantitative view. , 2007, Annual review of biochemistry.

[42]  M. Endo,et al.  LIM Kinase and Slingshot Are Critical for Neurite Extension* , 2007, Journal of Biological Chemistry.

[43]  E. Andrianantoandro,et al.  Mechanism of actin filament turnover by severing and nucleation at different concentrations of ADF/cofilin. , 2006, Molecular cell.

[44]  J. Ratnanather,et al.  Electromechanical Models of the Outer Hair Cell Composite Membrane , 2006, The Journal of Membrane Biology.

[45]  J. Niu,et al.  LIM Kinase 1 Coordinates Microtubule Stability and Actin Polymerization in Human Endothelial Cells* , 2005, Journal of Biological Chemistry.

[46]  Jinsong Meng,et al.  Regulation of ADF/cofilin phosphorylation and synaptic function by LIM-kinase , 2004, Neuropharmacology.

[47]  Adriana B Ferreira,et al.  LIMK1 regulates Golgi dynamics, traffic of Golgi-derived vesicles, and process extension in primary cultured neurons. , 2004, Molecular biology of the cell.

[48]  R. Mullins,et al.  Activation of Arp2/3 Complex: Addition of the First Subunit of the New Filament by a WASP Protein Triggers Rapid ATP Hydrolysis on Arp2 , 2004, PLoS biology.

[49]  Toshikazu Nakamura,et al.  LIM-kinase as a regulator of actin dynamics in spermatogenesis , 2004, Cytogenetic and Genome Research.

[50]  Yasuyuki Shima,et al.  Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin , 2003, Genes to cells : devoted to molecular & cellular mechanisms.

[51]  N. Kitamura,et al.  Cofilin phosphorylation and actin polymerization by NRK/NESK, a member of the germinal center kinase family. , 2003, Experimental cell research.

[52]  T. Uemura,et al.  Control of Growth Cone Motility and Morphology by LIM Kinase and Slingshot via Phosphorylation and Dephosphorylation of Cofilin , 2003, The Journal of Neuroscience.

[53]  Lawrence C. Katz,et al.  Odorant receptors instruct functional circuitry in the mouse olfactory bulb , 2002, Nature.

[54]  J. Macdonald,et al.  Abnormal Spine Morphology and Enhanced LTP in LIMK-1 Knockout Mice , 2002, Neuron.

[55]  T. Uemura,et al.  Control of Actin Reorganization by Slingshot, a Family of Phosphatases that Dephosphorylate ADF/Cofilin , 2002, Cell.

[56]  J. Miyazaki,et al.  Impaired spermatogenic ability of testicular germ cells in mice deficient in the LIM-kinase 2 gene. , 2002, Developmental biology.

[57]  K. Mizuno,et al.  Cofilin Phosphorylation and Actin Reorganization Activities of Testicular Protein Kinase 2 and Its Predominant Expression in Testicular Sertoli Cells* , 2001, The Journal of Biological Chemistry.

[58]  Y. Takai,et al.  Cofilin Phosphorylation and Actin Cytoskeletal Dynamics Regulated by Rho- and Cdc42-Activated Lim-Kinase 2 , 1999, The Journal of cell biology.

[59]  S. Nomoto,et al.  Cloning and characterization of the alternative promoter regions of the human LIMK2 gene responsible for alternative transcripts with tissue-specific expression. , 1999, Gene.

[60]  D. Fekete,et al.  Hair Cells and Supporting Cells Share a Common Progenitor in the Avian Inner Ear , 1998, The Journal of Neuroscience.

[61]  E. Nishida,et al.  Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization , 1998, Nature.

[62]  M. Hirai,et al.  Identification and Characterization of a Novel Family of Serine/Threonine Kinases Containing Two N-terminal LIM Motifs (*) , 1995, The Journal of Biological Chemistry.

[63]  K. Ohashi,et al.  LIMK-1 and LIMK-2, two members of a LIM motif-containing protein kinase family. , 1995, Oncogene.

[64]  K. Kuma,et al.  Identification of a human cDNA encoding a novel protein kinase with two repeats of the LIM/double zinc finger motif. , 1994, Oncogene.

[65]  A. Gautreau,et al.  The Arp2/3 Regulatory System and Its Deregulation in Cancer. , 2018, Physiological reviews.

[66]  B. Kachar,et al.  Review series The cell biology of hearing , 2010 .

[67]  R. Fettiplace,et al.  The sensory and motor roles of auditory hair cells , 2006, Nature Reviews Neuroscience.

[68]  M. Ross,et al.  Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility , 2006, Nature Neuroscience.