Heterogeneity in the in vitro susceptibility of Loa loa microfilariae to drugs commonly used in parasitological infections

[1]  A. Hoerauf,et al.  Successful long-term maintenance of Mansonella perstans in an in vitro culture system , 2017, Parasites & Vectors.

[2]  D. Helmy,et al.  Therapeutic effect of mefloquine on Schistosoma mansoni in experimental infection in mice , 2016, Journal of Parasitic Diseases.

[3]  P. Enyong,et al.  Parasitological, Hematological and Biochemical Characteristics of a Model of Hyper-microfilariaemic Loiasis (Loa loa) in the Baboon (Papio anubis) , 2015, PLoS neglected tropical diseases.

[4]  M. Bockarie,et al.  Cross-Reactivity of Filariais ICT Cards in Areas of Contrasting Endemicity of Loa loa and Mansonella perstans in Cameroon: Implications for Shrinking of the Lymphatic Filariasis Map in the Central African Region , 2015, PLoS neglected tropical diseases.

[5]  Michael A Dolan,et al.  Targeting Filarial Abl-like Kinases: Orally Available, Food and Drug Administration-Approved Tyrosine Kinase Inhibitors Are Microfilaricidal and Macrofilaricidal. , 2015, The Journal of infectious diseases.

[6]  T. Geary,et al.  Adding "Filaricide" to the Gleevec Portfolio. , 2015, The Journal of infectious diseases.

[7]  M. Boussinesq,et al.  Analysis of Nematode Motion Using an Improved Light-Scatter Based System , 2015, PLoS neglected tropical diseases.

[8]  G. Weil,et al.  Filarial Antigenemia and Loa loa Night Blood Microfilaremia in an Area Without Bancroftian Filariasis in the Democratic Republic of Congo , 2014, The American journal of tropical medicine and hygiene.

[9]  J. Utzinger,et al.  Praziquantel, Mefloquine-Praziquantel, and Mefloquine-Artesunate-Praziquantel against Schistosoma haematobium: A Randomized, Exploratory, Open-Label Trial , 2014, PLoS neglected tropical diseases.

[10]  S. Fahmy,et al.  The potential role of mefloquine against Schistosoma mansoni infection by prohibition of hepatic oxidative stress in mice , 2014 .

[11]  M. A. Bray,et al.  Determination of an Optimal Dosing Regimen for Fexinidazole, a Novel Oral Drug for the Treatment of Human African Trypanosomiasis: First-in-Human Studies , 2014, Clinical Pharmacokinetics.

[12]  Kentaro Kato,et al.  In vitro effects of amodiaquine on paired Schistosoma mansoni adult worms at concentrations of less than 5 µg/mL. , 2013, Memorias do Instituto Oswaldo Cruz.

[13]  P. Mäser,et al.  Antiparasitic agents: new drugs on the horizon. , 2012, Current opinion in pharmacology.

[14]  M. Gismondo,et al.  Imported Loa loa filariasis: three cases and a review of cases reported in non-endemic countries in the past 25 years. , 2012, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

[15]  A. Hoerauf,et al.  The human parasite Loa loa in cytokine and cytokine receptor gene knock out BALB/c mice: survival, development and localization , 2012, Parasites & Vectors.

[16]  B. Ollomo,et al.  Epidemiology of Concomitant Infection Due to Loa loa and Mansonella perstans in Gabon , 2011, PLoS neglected tropical diseases.

[17]  M. A. Bray,et al.  Antitrypanosomal Activity of Fexinidazole, a New Oral Nitroimidazole Drug Candidate for Treatment of Sleeping Sickness , 2011, Antimicrobial Agents and Chemotherapy.

[18]  P. Diggle,et al.  The Geographic Distribution of Loa loa in Africa: Results of Large-Scale Implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA) , 2011, PLoS neglected tropical diseases.

[19]  B. Nare,et al.  SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis , 2011, PLoS neglected tropical diseases.

[20]  T. Geary,et al.  Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs , 2011, Expert review of anti-infective therapy.

[21]  David Tweats,et al.  Fexinidazole – A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness , 2010, PLoS neglected tropical diseases.

[22]  T. Geary,et al.  Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi , 2010, Proceedings of the National Academy of Sciences.

[23]  E. Fèvre,et al.  INTERNATIONAL JOURNAL OF HEALTH GEOGRAPHICS RESEARCH Open Access The Atlas of human African trypanosomiasis: a , 2022 .

[24]  A. Souza,et al.  In vitro activities of plant extracts on human Loa loa isolates and cytotoxicity for eukaryotic cells , 2010, Parasitology Research.

[25]  J. Akue,et al.  Production and immunological characterization of a recombinant subunit of a Loa loa polyprotein antigen , 2010, Parasitology.

[26]  M. Boussinesq,et al.  A controlled trial to assess the effect of quinine, chloroquine, amodiaquine, and artesunate on Loa loa microfilaremia. , 2010, The American journal of tropical medicine and hygiene.

[27]  B. Makepeace,et al.  UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle , 2008, Parasites & Vectors.

[28]  M. Boussinesq,et al.  Encephalopathy after ivermectin treatment in a patient infected with Loa loa and Plasmodium spp. , 2008, The American journal of tropical medicine and hygiene.

[29]  F. Rumjanek,et al.  Inhibition of heme aggregation by chloroquine reduces Schistosoma mansoni infection. , 2004, The Journal of infectious diseases.

[30]  P. Enyong,et al.  Chrysops silacea biting densities and transmission potential in an endemic area of human loiasis in south‐west Cameroon , 2002, Tropical medicine & international health : TM & IH.

[31]  M. Boussinesq,et al.  Serious reactions after mass treatment of onchocerciasis with ivermectin in an area endemic for Loa loa infection , 1997, The Lancet.

[32]  M. Boussinesq,et al.  Severe adverse reaction risks during mass treatment with ivermectin in loiasis-endemic areas. , 1996, Parasitology today.

[33]  P. Cooper,et al.  The effect of antimalarial chloroquine therapy and prophylaxis on concurrent infection with Onchocerca volvulus in Ecuador. , 1991, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[34]  J. Comley,et al.  The further application of MTT-formazan colorimetry to studies on filarial worm viability. , 1989, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

[35]  J. Comley,et al.  Colorimetric quantitation of filarial viability. , 1989, International journal for parasitology.

[36]  I. van Kerckhoven,et al.  Macrofilaricidal activity of oral flubendazole on Brugia pahangi. , 1988, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[37]  C. Connelly,et al.  Chemotherapy of Onchocerca lienalis microfilariae in mice: a model for the evaluation of novel compounds for the treatment of onchocerciasis , 1988, Journal of Helminthology.

[38]  Clive Hollands,et al.  THE ANIMALS (SCIENTIFIC PROCEDURES) ACT 1986 , 1986, The Lancet.

[39]  Orihel Tc,et al.  Loa loa: development and course of patency in experimentally-infected primates. , 1985 .

[40]  H. Francis,et al.  The Mazzotti reaction following treatment of onchocerciasis with diethylcarbamazine: clinical severity as a function of infection intensity. , 1985, The American journal of tropical medicine and hygiene.

[41]  R. Chandrashekar,et al.  Isolation of microfilariae from blood on iso-osmotic percoll gradients. , 1984, The Indian journal of medical research.

[42]  E. Devaney,et al.  The microfilaricidal activity of ivermectin in vitro and in vivo. , 1984, Tropenmedizin und Parasitologie.

[43]  R. Murphy,et al.  COMPARISON OF FLUBENDAZOLE AND DIETHYLCARBAMAZINE IN TREATMENT OF ONCHOCERCIASIS , 1983, The Lancet.

[44]  T. C. Orihel,et al.  Loa loa: experimental infection in two species of African primates. , 1975, The American journal of tropical medicine and hygiene.

[45]  T. Geary,et al.  Potential Role for Flubendazole in Limiting Filariasis Transmission: Observations of Microfilarial Sensitivity. , 2018, The American journal of tropical medicine and hygiene.

[46]  S. Tardif,et al.  The Baboon in Biomedical Research , 2009 .

[47]  A. Jitpakdi,et al.  Comparative assessment of the in vitro sensitivity of Brugia malayi infective larvae to albendazole, diethylcarbamazine and ivermectin alone and in combination. , 2004, The Southeast Asian journal of tropical medicine and public health.

[48]  G. Schares,et al.  Experimental chemotherapy of filariasis: comparative evaluation of the efficacy of filaricidal compounds in Mastomys coucha infected with Litomosoides carinii, Acanthocheilonema viteae, Brugia malayi and B. pahangi. , 1993, Acta tropica.

[49]  B. Ivanoff,et al.  A rapid, simple method for isolation of viable microfilariae. , 1986, The American journal of tropical medicine and hygiene.

[50]  G. Boulesteix,et al.  Encéphalite au cours du traitement de la filariose à Loa loa par la diéthylcarbamazine. A propos de 6 observations , 1986 .

[51]  M. Eberhard,et al.  Loa loa: development and course of patency in experimentally-infected primates. , 1985, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.

[52]  J. Mak.  Antifilarial activity of mebendazole and flubendazole on Breinlia booliati. , 1981, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[53]  D. Denham,et al.  The anthelmintic effects of flubendazole on Brugia pahangi. , 1979, Transactions of the Royal Society of Tropical Medicine and Hygiene.