The “Flexcell” of the American Company Flexcell International represented in Europe by Dunn Labortechnik induces biochemical changes in response to applied strain or compression in cells. Flexcell Tension & Compression Systems: Computer regulated bioreactors that apply cyclic or static tensile strains or compression to cells cultured in vitro. Tissue Train Culture System: 3D cell culture in a gel matrix with or without cyclic uniaxial tension. ScanFlex: Scans and saves images of 3D tissue constructs. Microscopy Device: A single-well embodiment of the Tension or Compression apparatus to observe signaling responses to strain in real time on a microscope stage. Flow Devices: Apply fluid shear stress to cells. Osci-Flow: Flow controller for regulated oscillatory and pulsatile flow control. Syringe Pump: Controlling fluid flow at the micro, nano and picofluidic levels.