Transcutaneous Bladder Spectroscopy: Computer Aided Near Infrared Monitoring of Physiologic Function

Transcutaneous bladder spectroscopy is a novel non-invasive optical technique that uses near infrared (NIR) light to detect changes in concentration of the tissue chromophores oxy and deoxy-hemoglobin in the anterior wall of the organ as it fills and empties. From the patterns, trends and magnitude of these changes alterations in tissue oxygenation and hemodynamics can be inferred, and, as these differ in health and disease, novel information is gained related to the pathophysiology underlying the causation and symptoms of voiding dysfunction. Following proof of concept and a series of clinical studies, evolution of NIR spectroscopy (NIRS) devices for bladder study now requires computer aided solutions to optimize device design and refine software development to further advance application of this technology. We review the concept of bladder spectroscopy, summarize the evolution of related NIRS hardware and software, and outline the challenges and potential for further computer aided development.

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