FURTHER EXPERIENCE WITH THE RADIO TRANSMITTER RECEIVER UNIT FOR THE NEUROGENIC BLADDER.

UCCESSFUL evacuation of the neurogenic bladder in dogs with the radiofrequency receiver-stimulator has been described in a preliminary report? In this communication stimulating parameters capable of evoking evacuation of the bladder were described. A biphasic pulse, 5-15 volts in amplitude and 1-5 msec. in duration, was found effective. An implantable receiverstimulator powered by an external, detached radio transmitter was then designed in accordance with these parameters. Neurogenic bladders in dogs produced by transection of the spinal cord at the cervicothoracic junction or by section of the cauda equina could be emptied by such stimulation in either acute or chronic experimental conditions. Completeness of emptying was assessed using the cystogram and cineroentgenogram. These roentgenographic studies indicated the effectiveness of the device to evoke regular evacuation of the neurogenic bladder on a 4-8 hourly basis. Cultures of urine and tests for renal function demonstrated the ability of the instrument to prevent infection and to avoid renal impairment. Such study of the neurogenic bladder in dogs has now been extended and application of this technique in patients has been explored. It is the purpose of this report to describe the problems encountered and the solutions offered in the experimental animals and to discuss the results of clinical studies. Animals Experiments