Interactive Liver Segmentation in CT Volumes Using Fully Convolutional Networks

Organ segmentation is one of the most fundamental and challenging task in computer aided diagnosis (CAD) systems, and segmenting liver from 3D medical data becomes one of the hot research topics in medical analysis field. Graph cut algorithms have been successfully applied to medical image segmentation of different organs for 3D volume data which not only leads to very large-scale graph due to the same node number as voxel number. Slice by Slice liver segmentation method is one of the technique that normally used to solve the memory usage. However, the computation times are increased and reduce the accuracy. In this paper we propose an interactive organ segmentation using fully convolutional networks. The network will perform slice by slice which only 1 slice of seed points in each volume. To validate effectiveness and efficiency of our proposed method, we conduct experiments on 20 CT volumes, focus on liver organ and most of which have tumors inside of the liver, and abnormal deformed shape of liver. Our method can segment with 0.95401 dice accuracy with better than stage-of-the-art methods.

[1]  Xinjian Chen,et al.  Automatic Liver Segmentation Based on Shape Constraints and Deformable Graph Cut in CT Images , 2015, IEEE Transactions on Image Processing.

[2]  Matthias Kirschner,et al.  Fast automatic liver segmentation combining learned shape priors with observed shape deviation , 2010, 2010 IEEE 23rd International Symposium on Computer-Based Medical Systems (CBMS).

[3]  Geoffrey E. Hinton,et al.  ImageNet classification with deep convolutional neural networks , 2012, Commun. ACM.

[4]  J. Sethian,et al.  Fronts propagating with curvature-dependent speed: algorithms based on Hamilton-Jacobi formulations , 1988 .

[5]  Yen-Wei Chen,et al.  Simultaneous Segmentation of Multiple Organs Using Random Walks , 2016, J. Inf. Process..

[6]  Marie-Pierre Jolly,et al.  Interactive graph cuts for optimal boundary & region segmentation of objects in N-D images , 2001, Proceedings Eighth IEEE International Conference on Computer Vision. ICCV 2001.

[7]  Leo Grady,et al.  Random Walks for Image Segmentation , 2006, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[8]  Thomas Lange,et al.  A Statistical Shape Model for the Liver , 2002, MICCAI.

[9]  Yen-Wei Chen,et al.  Segmentation of liver and spleen based on computational anatomy models , 2015, Comput. Biol. Medicine.

[10]  Hervé Delingette,et al.  Regional appearance modeling based on the clustering of intensity profiles , 2013, Comput. Vis. Image Underst..

[11]  Yen-Wei Chen,et al.  Liver segmentation using superpixel-based graph cuts and restricted regions of shape constrains , 2015, 2015 IEEE International Conference on Image Processing (ICIP).